Advances in Cancer Immunotherapy

A special issue of Applied Sciences (ISSN 2076-3417). This special issue belongs to the section "Applied Biosciences and Bioengineering".

Deadline for manuscript submissions: closed (20 January 2022) | Viewed by 1814

Special Issue Editor


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Guest Editor
Department of Biomedical Sciences, Faculty of Health Sciences, University of West Attica, 12243 Athens, Greece
Interests: clinical pharmacology; surgical oncology; immune-oncology; drug targeting; drug safety; breast cancer; endocrine cancer; colorectal cancer; familial cancer
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Special Issue Information

Dear Colleagues,

Cancer immunotherapy has become a powerful new approach to cancer therapy. Immunotherapy drugs have already been approved by the FDA for the treatment of multiple types of cancers, thus enhancing research interest in the field of cancer immunotherapy. Progress in cancer immunotherapy has largely been facilitated by relevant technological progress. New technologies such as next-generation sequencing have enhanced our ability to search for new targets in immuno-oncology. On the other hand, drug delivery systems such as nanoparticles and the use of T cells for drug delivery have enabled an increase in potency and the reduction of adverse events associated with cancer immunotherapy. This Special Issue is devoted to advanced technologies that lead to the implementation of cancer immunotherapy.

Dr. Eugenia Yiannakopoulou
Guest Editor

Manuscript Submission Information

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Keywords

  • cancer immunotherapy
  • next-generation sequencing
  • drug delivery technologies
  • nanoparticles
  • modulation of the immune system

Published Papers (1 paper)

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Review

10 pages, 545 KiB  
Review
The Influence of Diet and Probiotics on the Response of Solid Tumours to Immunotherapy: Present and Future Perspectives
by Alejandro Olivares-Hernández, Luis Figuero-Pérez, Rogelio González-Sarmiento, David León-Jiménez, Juan Jesús Cruz-Hernández and José Pablo Miramontes-González
Appl. Sci. 2021, 11(18), 8445; https://doi.org/10.3390/app11188445 - 11 Sep 2021
Cited by 2 | Viewed by 1483
Abstract
Currently, various immunotherapeutic treatments are revolutionizing therapies that treat solid neoplasms. For these treatments, within immunotherapy, immune checkpoint inhibitors (ICIs) are the most widely used drugs. Diverse studies have shown the influence of diet and probiotics on the response to ICIs and consequently [...] Read more.
Currently, various immunotherapeutic treatments are revolutionizing therapies that treat solid neoplasms. For these treatments, within immunotherapy, immune checkpoint inhibitors (ICIs) are the most widely used drugs. Diverse studies have shown the influence of diet and probiotics on the response to ICIs and consequently on the survival rates associated with different neoplasms. The use of various antibiotics, probiotics, and prebiotics has been associated with changes in the gut microbiota, and this, in turn, with resistance to immunotherapy. Together with the above, a lower intake of red meat and greater consumption of a Mediterranean, vegetarian, or vegan diet have led to a new way of understanding the mechanisms of resistance to ICIs. Omega-3 and polyphenol supplements are also powerful regulators of the microbiome whose influence on the immune system. Therefore, this review covers the influence of diet and probiotics on the response to immunotherapy in patients who have solid tumours. Full article
(This article belongs to the Special Issue Advances in Cancer Immunotherapy)
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