Oxidative Stress Generation and Application for Cancer Therapy

Dear Colleagues,

Oxidative stress is widely involved with pathogenesis including cancer, neurodegenerative disease and cardiovascular disease. Oxidative stress state is caused by generation of excess amounts of reactive oxygen species (ROS) and following redox imbalance. While ROS develop many kinds of disease via various signaling pathways, it is also useful for the therapy such as radiation and photodynamic therapy. Recently, it is reported that ROS generation caused by treatment of anti-cancer drug shows anti-cancer effect and accumulation of drugs in tumor cells. This special issue focuses on the cancer therapy regarding ROS generation and oxidative stress including in vitro and in vivo studies.

Dr. Hiromu Ito
Guest Editor

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