Developing New Tools for Vibrational Spectroscopy for Biomedical and Environmental Applications
A special issue of Applied Sciences (ISSN 2076-3417). This special issue belongs to the section "Chemical and Molecular Sciences".
Deadline for manuscript submissions: 30 June 2026 | Viewed by 10
Special Issue Editors
Interests: infrared spectroscopy; FT-IR; biosensor design and development
Special Issues, Collections and Topics in MDPI journals
Interests: infrared spectroscopy; FT-IR; optical biosensor design and development; fluorescence; two-photon microscopy
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Vibrational spectroscopy, including near-infrared (NIR), Fourier-transform Infrared (FTIR), and Raman spectroscopy, has emerged as a powerful non-destructive tool for analysing chemical bonds and molecular structures, and studying structural changes during processing.
In recent years, significant advancements in instrumentation, computational analysis, and hybrid technologies have driven a transformative evolution in vibrational spectroscopy's capabilities. These emerging tools address long-standing challenges such as limited spatial resolution, low sensitivity, and slow acquisition times, and enable vibrational spectroscopy to play an important role in Industry 4.0.
Among the most notable innovations are quantum cascade lasers (QCLs) that revolutionise mid-infrared spectroscopy, surface-enhanced Raman spectroscopy (SERS), and tip-enhanced Raman spectroscopy (TERS) for nanoscale study, advancements in chemometric approaches and AI-driven spectral interpretation that improve the accuracy and interpretability of the data, and real-time monitoring. Additionally, the development of portable Raman and IR spectrometers and advanced imaging modalities is expanding the applicability of vibrational spectroscopy from traditional laboratory settings to fieldwork.
Over the years, these new tools and spectroscopic techniques are expanding the application of vibrational spectroscopy across different fields such as the biomedical and environmental one due to their high specificity, and ability to provide molecular-level insights into complex biological systems, making them an invaluable tool for applications in diagnostics, disease monitoring, and therapeutic development and also for studying water and soil quality and environmental changes.
Dr. Marianna Portaccio
Dr. Maria Lepore
Guest Editors
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Keywords
- fourier-transform infrared spectroscopy (FTIR)
- raman spectroscopy
- surface-enhanced Raman spectroscopy (SERS)
- tip-enhanced Raman spectroscopy (TERS)
- stimulated Raman spectroscopy
- coherent anti-Stokes Raman scattering spectroscopy (CARS)
- brillouin vibrational spectroscopy
- quantum cascade lasers (QCLs)
- biomedical infrared spectroscopy
- environmental infrared spectroscopy
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