Synthesis of Natural or Unnatural Bioactive Compounds and Novel Molecular Frameworks

Dear Colleagues,

The area of organic synthesis—the "art" of building complex organic molecular structures from smaller chemical entities—lies at the heart of chemistry. Such molecules facilitate biology and medicine, as they often find uses in many areas of science, technology and everyday life. Synthetic organic chemistry has played an increasing role in the development of new molecular architecture, with combinations of properties that will underpin future medicinal chemistry advancements. The unforeseen discoveries and development in the field will best be unraveled by detailed structure−activity relationship studies. Access to natural products and their analogues is crucial in the area of drug discovery and chemical biology. It is clear that Nature will continue to be a major source of new structural leads and provide inspiration in developing synthetic methods, in the quest for making new chemical entities.

This Special Issue is a showcase for some spectacular research in the area of synthesis of natural and unnatural bioactive compounds. Contributions to this issue will be concentrated on, but not limited to, the synthesis of bioactive natural products, novel molecular frameworks, and unnatural compounds of medicinal relevance.

Prof. Dr. Nisar Ullah
Guest Editor

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• natural products
• medicinal chemistry
• novel molecular frameworks
• new methodologies in organic synthesis