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Engineering Neurotechnology: Bridging Point-of-Care and Organ-on-a-Chip Solutions for Personalized Medicine

A special issue of Applied Sciences (ISSN 2076-3417). This special issue belongs to the section "Applied Neuroscience and Neural Engineering".

Deadline for manuscript submissions: 31 October 2025 | Viewed by 31

Special Issue Editors


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Guest Editor
INL—International Iberian Nanotechnology Laboratory, Av. Mte. José Veiga s/n, Braga, Portugal
Interests: early disease detection and frontline healthcare applications; POC systems; AI-driven diagnostic technologies; lab-on-a-chip biosensing; neurodegeneration, neuroinflammation; macrophages

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Guest Editor
INL—International Iberian Nanotechnology Laboratory, Av. Mte. José Veiga s/n, Braga, Portugal
Interests: PoC systems; biosensors; biointerfaces; stroke; biomarkers related to neurologic disorders

Special Issue Information

Dear Colleagues,

Neuroscience and neural engineering are rapidly transforming personalized medicine through the creation of innovative solutions to neurological disorders. This Special Issue highlights cutting-edge research in applied neuroscience and neural engineering, advancing personalized diagnostics, disease monitoring, and therapeutic interventions.

Its focus includes microphysiological systems that mimic neural interactions with peripheral organs, such as organ-on-a-chip (OoC) platforms, and brain-on-a-chip systems for disease modeling and therapeutic screening. We invite submissions that cover innovative neurotechnologies, including point-of-care (POC) devices, biosensors, neural interfaces, and implantable systems for real-time monitoring. Bioengineered systems that integrate molecular diagnostics with artificial intelligence (AI) are particularly interesting, given their potential for enhancing diagnostic accuracy and treatment efficacy. Personalized approaches to neurodegenerative, neuroinflammatory, neurodevelopmental, and neuro-oncological conditions are encouraged. We also welcome research elucidating the molecular pathways, genetic factors, and cellular mechanisms underlying neurological disorders. Advances in molecular diagnostics, biomarkers, and targeted therapies are central to enhancing personalized medical approaches.

Engineering technologies are crucial for developing new therapeutics and advancing biomarker-related POC diagnostics in neurological diseases. We welcome the submission of original research, reviews, and case studies exploring these topics to this Special Issue.

Dr. Carole Sousa
Dr. Elisabete Fernandes
Dr. Diana Pinho
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Applied Sciences is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2400 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • molecular neuroscience
  • neural engineering
  • personalized neurotechnology
  • brain–computer interfaces
  • point-of-care neurodiagnostics
  • organ-on-a-chip systems
  • microfluidics
  • biosensors
  • AI-integrated neurotechnologies
  • translational neuroscience
  • neurological disorder modeling

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