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Advances in Orthodontic Treatment, 2nd Edition

A special issue of Applied Sciences (ISSN 2076-3417). This special issue belongs to the section "Applied Biosciences and Bioengineering".

Deadline for manuscript submissions: 20 April 2026 | Viewed by 441

Special Issue Editors


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Guest Editor
Dentistry Unit, Management Innovations, Diagnostics and Clinical Pathways, Bambino Gesù Children’s Hospital, IRCCS, 00165 Rome, Italy
Interests: orthodontics; pediatric dentistry; dentistry; anatomy; artificial intelligence; technologies; forensic odontology
Special Issues, Collections and Topics in MDPI journals

E-Mail Website
Guest Editor
Dentistry Unit, Management Innovations, Diagnostics and Clinical Pathways, Bam-Bino Gesù Children’s Hospital, IRCCS, 00165 Rome, Italy
Interests: pediatric dentistry; orthodontics; conservative dentistry; endodontics; technologies; genetics; sedation; oral surgery; caries; hygiene; public health; rare diseases; special needs; public health management
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

This Special Issue aims to investigate the most recent advances in orthodontic treatment. New technologies and methods recently developed have provided patients with more aesthetic and comfortable options, better analysis, and treatment planning. This improvement, mainly driven by 3D technologies and artificial intelligence in an attempt to make quicker treatments, is also intended to simplify the orthodontist's work without reducing, or even increasing, the efficiency of therapies and their long-term success. All these aspects affect both adult orthodontics and the treatment of growing subjects. Orthodontic retreatments and orthodontic therapies on fragile/vulnerable subjects (pediatric or adult) or requiring an integrated multi-specialist approach (medical/dental) often represent a clinical challenge in which new technologies and new advances can make a difference. Studies that include ethical and medico-legal implications and considerations on the use of new technologies and new advances in the orthodontic field constitute preferential contributions. Scientific contributions in the form of research articles and reviews are welcome. Case reports/series on these topics will be evaluated.

Dr. Alessandra Putrino
Dr. Angela Galeotti
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Applied Sciences is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2400 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • orthodontics
  • 3D technologies
  • artificial intelligence
  • multidisciplinary approach
  • medico-legal
  • pediatric dentistry
  • adult orthodontics
  • tooth movement
  • skeletal development
  • malocclusion
  • relapse prevention
  • hybrid therapies
  • orthodontic retreatment
  • fixed appliances
  • removable appliances
  • clear aligners

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Published Papers (1 paper)

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16 pages, 578 KB  
Systematic Review
Biomechanical Insights into the Variation of Maxillary Arch Dimension with Clear Aligners: A Finite Element Analysis-Based Scoping Review
by Alessandra Putrino, Gaia Bompiani, Francesco Aristei, Valerio Fornari, Ludovico Massafra, Roberto Uomo and Angela Galeotti
Appl. Sci. 2025, 15(17), 9514; https://doi.org/10.3390/app15179514 - 29 Aug 2025
Viewed by 356
Abstract
Clear aligners (CAs) have emerged as a widely accepted alternative to conventional fixed orthodontic appliances due to their aesthetic appeal, comfort, and removability. Despite their increasing use, the precise biomechanical behavior of CAs—particularly in relation to maxillary arch expansion and torque control—remains incompletely [...] Read more.
Clear aligners (CAs) have emerged as a widely accepted alternative to conventional fixed orthodontic appliances due to their aesthetic appeal, comfort, and removability. Despite their increasing use, the precise biomechanical behavior of CAs—particularly in relation to maxillary arch expansion and torque control—remains incompletely understood. This scoping review aims to synthesize and critically examine the recent body of evidence derived from finite element analysis (FEA) studies investigating the performance of clear aligners in managing transverse discrepancies and controlling tooth movement. It considered studies published up to April 2025. All included FEA studies assumed dental and bone tissues as linearly elastic, homogeneous, and isotropic, unless otherwise specified. Five in silico studies were included, all employing three-dimensional FEA models to assess the influence of various clinical and design parameters, such as aligner thickness, movement sequence, attachment configuration, and torque compensation. The findings consistently show that movement protocols involving alternating activation patterns and specific attachment designs can significantly improve the efficiency of maxillary expansion, while reducing undesired tipping or anchorage loss. Additionally, greater aligner thicknesses were generally associated with increased force delivery and more pronounced tooth displacement. Although FEA provides a powerful tool for visualizing stress distribution and predicting mechanical responses under controlled conditions, the lack of standardized force application and limited clinical validation remain important limitations. These findings underscore the potential of optimized aligner protocols to enhance treatment outcomes, but they also highlight the need for complementary in vivo studies to confirm their clinical relevance and guide evidence-based practice. Full article
(This article belongs to the Special Issue Advances in Orthodontic Treatment, 2nd Edition)
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