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Applied Sciences
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Applied Biomaterials for Dental Implantology: Researches and Applications
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Applied Biomaterials for Dental Implantology: Researches and Applications

A special issue of Applied Sciences (ISSN 2076-3417). This special issue belongs to the section "Applied Biosciences and Bioengineering".

Deadline for manuscript submissions: 20 March 2026 | Viewed by 3785

Special Issue Editors

Dr. Paolo Carosi

E-Mail Website
Guest Editor
Department of Chemical Science and Technologies, University of Rome “Tor Vergata”, 00033 Rome, Italy
Interests: static-guided surgery; dynamic-guided surgery; immediate loading; immediate implant placement
Special Issues, Collections and Topics in MDPI journals
Dr. Claudia Lorenzi

E-Mail Website
Guest Editor
Department of Chemical Science and Technologies, PhD in Materials for Health, Environment and Energy–Dentistry, University of Rome Tor Vergata, 00133 Rome, Italy
Interests: computer-guided surgery; navigation surgery; digital implantology; stereophotogrammetry; complete-arch rehabilitation
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

The ongoing development of new technologies, together with novel biomaterials and modified implant surfaces, have begun to rewrite the overall success of rehabilitation in dentistry. Enhancing implant stability over time with innovative biomaterials, in combination with more hydrophilic surfaces, has presented a valid solution to set the peri-implant hard and soft tissues, from single teeth to complete arches. These new biomaterials for bone and soft tissue regeneration, together with digital solutions in implant dentistry, have set a new benchmark in regenerative dentistry.

Dr. Paolo Carosi
Dr. Claudia Lorenzi
Guest Editors

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Keywords

  • computer-guided surgery
  • navigation surgery
  • robotic surgery
  • digital implantology
  • bone regeneration
  • soft tissue augmentation

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Published Papers (2 papers)

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Research

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14 pages, 600 KB  
Article
Dental Implants Rehabilitation in Patients with Vitamin D3 Imbalance: A Randomized Controlled Trial
by Ekaterina Diachkova, Marina Skachkova, Yuryi Zhilkov, Magamed Kerimov, Svetlana Tarasenko, Anna Babkova, Natalia Zhukova, Svetlana Bokareva, Silvio Taschieri, Alexey Unkovskiy, Olesya Kytko, Viktoria Zaborova, Elizaveta Kytko and Stefano Corbella
Appl. Sci. 2025, 15(17), 9490; https://doi.org/10.3390/app15179490 - 29 Aug 2025
Viewed by 530
Abstract
Background: Vitamin D3 is an important factor for bone metabolism, and its deficiency may affect dental implantation results. Materials and methods: 384 patients with a diagnosis of tooth loss and vitamin D deficiency were examined and treated with dental implants. Vitamin D3 supplements [...] Read more.
Background: Vitamin D3 is an important factor for bone metabolism, and its deficiency may affect dental implantation results. Materials and methods: 384 patients with a diagnosis of tooth loss and vitamin D deficiency were examined and treated with dental implants. Vitamin D3 supplements were prescribed by the endocrinologist for all patients in the individual dose. The patients were divided into two equal study groups (n = 192) depending on the dental implantation period: Group 1—operation after blood serum vitamin D3 level normalization; group 2—before reaching the reference level of vitamin D3. Follow-up examinations were performed on the day of dental implantation, 7 days later, 1, 3, 6, and 12 months later, and every 1 year after treatment (up to 10 years). Implant stability and peri-implant tissue condition were assessed with clinical and X-ray diagnostics. Patients also visited an endocrinologist 2 months after the start of the treatment, then every 6 months. Results: The target vitamin D3 level (30–60 ng/mL) (p < 0.001) was achieved in all patients after treatment. At the control examinations, peri-implantitis was diagnosed in 10 patients (2.6%). It was detected in the group of patients with severe vitamin D deficiency and vitamin D deficiency—2 (25%) and 8 (3.4%) patients; respectively (p < 0.05). There was no significant difference between groups for risk of complications or bone quality after treatment. Conclusions: Timely screening of vitamin D3 levels and the appropriate treatment by an endocrinologist in young and middle-aged patients allow for achieving 97.4% dental implantation success for a ten-year period. Full article
(This article belongs to the Special Issue Applied Biomaterials for Dental Implantology: Researches and Applications)
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Review

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10 pages, 464 KB  
Review
The Use of Ibuprofen Arginate in Pain Management Following Third Molar Surgery—A Scoping Review
by Claudia Lorenzi, Ilaria Cammarota, Vincenzo Mazzetti, Claudio Arcuri, Paolo Carosi and Alberto Maria Pujia
Appl. Sci. 2025, 15(2), 662; https://doi.org/10.3390/app15020662 - 11 Jan 2025
Viewed by 2791
Abstract
Background: The management of pain and inflammation after third molar extraction is essential for patient comfort and recovery. While conventional ibuprofen is widely used for pain relief, ibuprofen arginate, a formulation aimed at faster absorption, has shown potential for faster onset and enhanced [...] Read more.
Background: The management of pain and inflammation after third molar extraction is essential for patient comfort and recovery. While conventional ibuprofen is widely used for pain relief, ibuprofen arginate, a formulation aimed at faster absorption, has shown potential for faster onset and enhanced efficacy. The aim of the present scoping review was to assess current evidence on the effectiveness of ibuprofen arginate in reducing pain and inflammation following third molar extraction compared to conventional ibuprofen. Methods: A comprehensive literature search was conducted in the MEDLINE database for studies published between 2002 and 2024, focusing on ibuprofen arginate’s impact on postoperative sequelae after third molar extractions. The studies included randomized controlled trials, cohort studies, and case–control studies in English. Results: Four studies, with a combined sample of 1245 patients, met the inclusion criteria. The findings suggest that ibuprofen arginate (200/400 mg) offers a faster onset of pain relief, with significant effects noticeable within 1–2 h. At six hours post administration, pain control was found to be similar between ibuprofen arginate and conventional ibuprofen. Additionally, a study found that ibuprofen arginate (600 mg) reduced postoperative swelling more effectively, although its impact on trismus was limited. Conclusions: Ibuprofen arginate seems to offer quicker pain relief and better control of swelling after third molar extractions compared to regular ibuprofen, making it a promising option for faster recovery. However, more studies are needed to fully understand its benefits and potential uses. Full article
(This article belongs to the Special Issue Applied Biomaterials for Dental Implantology: Researches and Applications)
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