Special Issue "Research of Bioactive Peptides in Foods"
Deadline for manuscript submissions: 30 November 2020.
Interests: protein and peptide analysis with the HPLC, MS, 2D-PAGE methods; proteomics; peptidomics of food, bioinformatics and chemical information
In recent years, peptides have received increased interest as one of the most important classes of bioactive food components. They are important as nutraceutical and active components in foods designed to obtain health benefits above and beyond their nutritional function. Peptides sufficient in diet aimed on metabolic syndrome prevention may serve as an example of compounds providing such benefits. Contemporary research includes, e.g., the discovery of novel bioactive peptides in food products and new activities of known compounds. The design and optimization of technological processes aimed at peptide release is an important task for food science and technology. The development of research strategies (e.g., in vitro and in vivo assays as well as bioinformatics) and analytical methods for identification and quantitation of biopeptides is also receiving major attention. Taste is one of the crucial factors affecting the acceptance of peptide-containing food products by consumers.
This Special Issue, entitled “Research of Bioactive Peptides in Foods”, will cover a selection of recent research articles, short communications, reviews, as well as perspectives in the area of bioactive peptides of food origin.
Prof. Dr. Piotr Minkiewicz
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All papers will be peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Applied Sciences is an international peer-reviewed open access semimonthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 1800 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
- bioactive peptides of food origin
- in vivo, in vitro, and in silico studies
- peptide identification and determination
- release of peptides during food processing
- taste of peptides
The below list represents only planned manuscripts. Some of these manuscripts have not been received by the Editorial Office yet. Papers submitted to MDPI journals are subject to peer-review.
Title: Molecular Docking Analysis of Human Somatic and Testicular Angiotensin Converting Enzyme in Complexed with a Novel Tripeptide Gly-Val-Arg
Abstract: The structure-based drug design targeting domains of the angiotensin-I-converting enzyme (ACE) is important in the treatment of hypertension. The domain specificity inhibition of somatic and testicular ACE by tripeptide GVR isolated from grey oyster mushroom by binding to the specified active site of ACE was not described previously. Tripeptide GVR was used as a ligand while different types of ACE proteins were used as receptors. Molecular docking studies were carried out. Tripeptide GVR was significantly bound to the active site of C-domain of somatic ACE as compared to the N-domain. Although tripeptide GVR was mimicking captopril but a strong inhibition of C-domain and a weak inhibition of N-domain by GVR probably lead to the less significant side effects to the patients as compared to the strong non-domain specific inhibitor, captopril. Besides, the importance of arginine at the C-terminal of a peptide sequence to inhibit ACE significantly was also shown.