Technologies and Applications of 3D Bioprinting

Dear Colleagues,

Three-dimensional (3D) bioprinting represents one of the most transformative technological advances in modern pharmaceutical research, enabling precise spatial control over biological materials, living cells, and therapeutic agents. Driven by ongoing progress in biomaterial development, bioink formulation, computational modeling, and advanced manufacturing technologies, the capabilities of 3D bioprinting are rapidly expanding.

A current challenge—and opportunity—is to fully leverage these advances to address real-world needs in drug development, personalized medicine, regenerative therapies, and in vitro modeling. Three-dimensional bioprinting now offers unprecedented possibilities for patient-specific dosage forms, physiologically relevant disease models, controlled drug delivery systems, and high-throughput screening platforms. Studying such non-idealized, biologically complex systems in realistic environments remains essential for unlocking new insights into biological function and therapeutic performance.

This Special Issue welcomes articles that explore cutting-edge technologies and applications of 3D bioprinting in regenerative medicine and pharmaceutical research. Potential topics include, but are not limited to, the following:

• Development of advanced biomaterials and functional bioinks;
• Design and fabrication of scaffolds for drug delivery and personalized medicine;
• Responsive and stimuli-sensitive materials for biomedical applications;
• Computational modeling and simulation of 3D-printed constructs;
• Integration of bioprinting with high-throughput screening or organ-on-a-chip systems;
• Bioprinted models for disease, toxicity, or pharmacokinetic studies;
• Hybrid manufacturing approaches combining bioprinting with other fabrication methods;
• Case studies demonstrating industrial applications;
• Challenges, limitations, and future directions in 3D bioprinting technologies.

We welcome interdisciplinary contributions bridging pharmaceutical technology, biomedical engineering, materials science, and nanotechnology. Original research, review articles, and short communications are all encouraged.

We look forward to receiving your submissions.

Dr. Aikaterini-Theodora Chatzitaki
Dr. Konstantinos Tsongas
Guest Editors

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