Special Issue "Oxidative Stress and Neurodegenerative Diseases"
A special issue of Antioxidants (ISSN 2076-3921). This special issue belongs to the section "Health Outcomes of Antioxidants and Oxidative Stress".
Deadline for manuscript submissions: closed (30 September 2014).
Interests: ischemic brain injury; neurodegenerative diseases; aging; oxidative stress; cell signaling pathways
Imbalance between generation and elimination of free radicals leads to oxidative stress and free radicals mediated tissue injury. Many lines of evidence suggest that oxidative stress plays an important role in neuronal loss in several CNS degenerative disorders, such as Alzheimer’s disease, Parkinson’s disease, ischemic stroke, aging, and amyotrophic lateral sclerosis. Mitochondrial oxidative metabolism, NADPH oxidase, nitric oxide synthase, and phospholipids metabolism are potential sources of intracellular free radicals. It is well known that overproduction of free radicals produces damage to lipids, proteins and DNA and induces neuronal apoptosis or necrosis, however much work is needed to clarify the mechanisms by which excessive free radicals are generated in the diseased brain and the molecular mechanisms by which free radicals induce neuronal death. This Issue will allow publication of all aspects regarding oxidative stress and neurodegenerative diseases and of therapeutic strategies targeting free radical generation.
Prof. Dr. Wenlan Liu
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All papers will be peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Antioxidants is an international peer-reviewed open access monthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2000 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
- free radicals
- oxidative stress