Antioxidant and Cytotoxic Effects of Phytochemicals
A special issue of Antioxidants (ISSN 2076-3921). This special issue belongs to the section "Health Outcomes of Antioxidants and Oxidative Stress".
Deadline for manuscript submissions: closed (31 May 2024) | Viewed by 5300
Special Issue Editors
Interests: phytochemicals; oxidative stress; cancer; genotoxicity; in vitro toxicology; cancer cell death; nanotoxicology
Special Issues, Collections and Topics in MDPI journals
Interests: biological chemistry; antioxidants; anti-inflammatories; bioactive compounds; polyphenols
Special Issues, Collections and Topics in MDPI journals
Interests: cytotoxicity; genotoxicity; nanoparticles for biological applications; nanotoxicity; drug delivery
Special Issues, Collections and Topics in MDPI journals
Interests: in vitro cell culture; cytotoxicity; genotoxicity; cancer therapy; nanobiomedicine; nanotoxicology; human health; environmental toxicology
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Phytochemicals are plant metabolites with diverse functions, including protection against biotic and abiotic stress. Oxidative stress and reactive species (RS) accumulation are pathological features that are intrinsically related to the development of cancer-related diseases. The antioxidant properties of phytochemicals have been linked to their ability to scavenge RS and prevent cellular damage caused by oxidative stress. Additionally, many phytochemicals have been shown to exhibit cytotoxic effects against cancer cells, including proapoptotic effects, making them attractive therapeutic agents.
This Special Issue welcomes original research and reviews on the antioxidant and cytotoxic effects of phytochemicals. Articles pertaining to the physicochemical properties, bioactivity, and cell delivery of phytochemicals, and their potential use as therapeutic agents for cancer and other diseases, are welcome. This research covers both in vitro and in vivo studies related to any of the following topics: phytochemicals’ structure–function relationship; reactive species scavenging or the modulation of their production; the role of phytochemicals in antioxidant defense systems and pathways; inflammation; mitochondrial disfunction; DNA damage; cancer cell death; and optimal drug delivery.
We look forward to receiving your contributions.
Dr. José Miguel P. Ferreira de Oliveira
Dr. Daniela Ribeiro
Dr. Helena Oliveira
Dr. Verónica Bastos
Guest Editors
Manuscript Submission Information
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Keywords
- phenolic compounds
- Nrf2
- reactive species
- phytochemistry
- plant natural products
- redox signaling
- oxidative stress
- antioxidant systems
- cellular damage
- cell death pathways
- drug delivery
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