Dietary Antioxidants: Molecular Mechanisms, Health Benefits, and Therapeutic Potential

A special issue of Antioxidants (ISSN 2076-3921). This special issue belongs to the section "Health Outcomes of Antioxidants and Oxidative Stress".

Deadline for manuscript submissions: 31 August 2026 | Viewed by 168

Special Issue Editor

Special Issue Information

Dear Colleagues,

Dietary antioxidants include a diverse array of phytochemicals, vitamins, and natural compounds that maintain redox balance by neutralizing reactive oxygen species, supporting antioxidant defenses, and reducing oxidative stress-induced cellular damage. These compounds also quench free radicals and modulate redox-sensitive signaling pathways implicated in inflammation, mitochondrial function, cell death, and metabolic regulation.

This Special Issue, “Dietary Antioxidants: Molecular Mechanisms, Health Benefits, and Therapeutic Potential,” will provide a comprehensive overview of the significance and practical applications of dietary antioxidants for human health.

Original research and review articles are sought on the effects of natural antioxidants, such as polyphenols, carotenoids, vitamins, peptides, and novel phytochemicals, on antioxidant activity, bioavailability, and their interactions within complex food matrices. Submissions should address molecular pathways related to metabolism, inflammation, mitochondrial function, and cell signaling and elucidate interactions between antioxidants, gut microbiota, and host metabolism using advanced analytical, biochemical, and omics-based methodologies. Papers presenting clinical or epidemiological evidence regarding antioxidant-rich diets, their preventive roles in chronic diseases, and their therapeutic applications in metabolic, cardiovascular, neurodegenerative, and inflammatory disorders are encouraged. We also welcome contributions on innovative delivery systems, nanoformulations, and food-based strategies to enhance antioxidant stability and efficacy.

Dr. Irene Dini
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 250 words) can be sent to the Editorial Office for assessment.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Antioxidants is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2900 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • dietary antioxidants
  • oxidative stress
  • redox signaling
  • antioxidants bioavailability
  • gut microbiota interactions
  • chronic disease prevention
  • functional foods
  • nutraceuticals

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Published Papers

This special issue is now open for submission.
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