Harnessing Medicinal Plant Potential: Integrative Approaches from Breeding to Metabolomics

A special issue of Agronomy (ISSN 2073-4395). This special issue belongs to the section "Horticultural and Floricultural Crops".

Deadline for manuscript submissions: 31 August 2026 | Viewed by 1531

Editors


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Guest Editor
Centro de Desarrollo de Productos Bióticos, Instituto Politécnico Nacional, Calle CEPROBI No. 8, Col. San Isidro, Yautepec 62731, Morelos, Mexico
Interests: medicinal plants; plant cell tissue culture; molecular biology; metabolomics

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Guest Editor
Department of Plant Agriculture, Gosling Research Institute for Plant Preservation, University of Guelph, Guelph, ON N1G 2W1, Canada
Interests: in vitro plant conservation; crypreservation; phytochemical characterization; stress physiology
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Special Issue Information

Dear Colleagues,

Medicinal plants have been valued for generations, with traditional knowledge highlighting their benefits to human health. Modern scientific approaches continue to reveal the complexity of plant chemical profiles and their therapeutic relevance. Plants constantly adapt to environmental pressures through dynamic biosynthetic pathways, producing diverse metabolites that are essential for protection, communication, and survival, many of which have significant medicinal potential.

This Special Issue, “Harnessing Medicinal Plant Potential: Integrative Approaches from Breeding to Metabolomics”, highlights interdisciplinary research aimed at advancing our understanding of these dynamic biological processes. We invite contributions that investigate breeding strategies for trait improvement, in vitro and tissue culture methodologies, metabolomic profiling, bioactivity assessments, phytochemical characterization, and structure–function relationships of bioactive compounds in medicinal and edible plant species. By integrating these complementary fields, this Special Issue aims to deepen insight into the mechanisms that generate valuable plant metabolites and support the development of improved plant resources with health-promoting properties.

We welcome researchers to share their innovative findings and emerging technologies to understand the biochemical and biological potential of medicinal plants.

Dr. Alma Angélica Del Villar-Martínez
Dr. Mukund R. Shukla
Guest Editors

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Keywords

  • medicinal plants
  • in vitro culture
  • stress resilience
  • biosynthesis pathways
  • phytochemical characterization
  • metabolomics

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Published Papers (1 paper)

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Research

23 pages, 3286 KB  
Article
Genetic Diversity Analysis of American Ginseng (Panax quinquefolius L.) Accessions Based on Phenotypic Traits and SSR Markers
by Wenhao Jia, Xutong He, Liwen Feng, Shurui Wang, Bowen Guan, Xiyu Chen, Junbo Rong, Mengyang Zhang, Zhongliang Yang, Dandan Zhang, Youcheng Wang, Chunyue Fu, Xiujuan Lei, Jian Zhang and Yingping Wang
Agronomy 2026, 16(11), 1098; https://doi.org/10.3390/agronomy16111098 - 31 May 2026
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Abstract
American ginseng (Panax quinquefolius L.) is an important medicinal crop, but its improvement in China is limited by variety degeneration and a shortage of elite cultivars. In this study, phenotypic traits and simple sequence repeat (SSR) markers were integrated to evaluate the [...] Read more.
American ginseng (Panax quinquefolius L.) is an important medicinal crop, but its improvement in China is limited by variety degeneration and a shortage of elite cultivars. In this study, phenotypic traits and simple sequence repeat (SSR) markers were integrated to evaluate the genetic diversity of 51 selected accessions from major Chinese production regions. Phenotypic analysis showed that five of the 18 quantitative traits had phenotypic coefficients of variation exceeding 40%, mainly involving root traits such as fresh root weight and lateral root number. Broad-sense heritability for these root traits ranged from 61.70% to 74.80%, indicating substantial genetic contribution under standardized conditions. Principal component analysis identified five candidate elite accessions: CY3 and KD1 for tall stature and high yield, DH1 and LH2 for high ginsenoside content, and AT1 for well-developed lateral roots. A 12-accession representative subset was further proposed for conservation and pre-breeding. SSR-based clustering showed weak geographic differentiation, and Mantel analysis revealed no significant correlation between phenotypic and SSR-based genetic distances. These materials, together with the proposed accession-level conservation strategy, provide useful resources for germplasm preservation, parental selection, QTL mapping, and marker-assisted breeding. Full article
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