22 December 2023
Cells | Top Cited Papers in 2022 in the Section “Stem Cells”

Methodologies to Isolate and Purify Clinical Grade Extracellular Vesicles for Medical Applications”
by Asma Akbar, Farzaneh Malekian, Neda Baghban, Sai Priyanka Kodam and Mujib Ullah
Cells 2022, 11(2), 186; https://doi.org/10.3390/cells11020186
Available online: https://www.mdpi.com/2073-4409/11/2/186

“Regulating Endogenous Neural Stem Cell Activation to Promote Spinal Cord Injury Repair”
by Emily A. B. Gilbert, Nishanth Lakshman, Kylie S. K. Lau and Cindi M. Morshead
Cells 2022, 11(5), 846; https://doi.org/10.3390/cells11050846
Available online: https://www.mdpi.com/2073-4409/11/5/846

“Different Sourced Extracellular Vesicles and Their Potential Applications in Clinical Treatments”
by Leila Bahmani and Mujib Ullah
Cells 2022, 11(13), 1989; https://doi.org/10.3390/cells11131989
Available online: https://www.mdpi.com/2073-4409/11/13/1989

“Effects of Adipose-Derived Stem Cells and Their Conditioned Medium in a Human Ex Vivo Wound Model”
by Xiao Guo, Christoph Schaudinn, Ulrike Blume-Peytavi, Annika Vogt and Fiorenza Rancan
Cells 2022, 11(7), 1198; https://doi.org/10.3390/cells11071198
Available online: https://www.mdpi.com/2073-4409/11/7/1198

Neuroinflammation and Parkinson’s Disease—From Neurodegeneration to Therapeutic Opportunities
by Bruna Araújo, Rita Caridade-Silva, Carla Soares-Guedes, Joana Martins-Macedo, Eduardo D. Gomes, Susana Monteiro and Fábio G. Teixeira
Cells 2022, 11(18), 2908; https://doi.org/10.3390/cells11182908
Available online: https://www.mdpi.com/2073-4409/11/18/2908

“Current Status and Challenges of Human Induced Pluripotent Stem Cell-Derived Liver Models in Drug Discovery”
by Tine Tricot, Catherine M. Verfaillie and Manoj Kumar
Cells 2022, 11(3), 442; https://doi.org/10.3390/cells11030442
Available online: https://www.mdpi.com/2073-4409/11/3/442

“Interaction of Neural Stem Cells (NSCs) and Mesenchymal Stem Cells (MSCs) as a Promising Approach in Brain Study and Nerve Regeneration”
by Agnieszka Kaminska, Klaudia Radoszkiewicz, Paulina Rybkowska, Aleksandra Wedzinska and Anna Sarnowska
Cells 2022, 11(9), 1464; https://doi.org/10.3390/cells11091464
Available online: https://www.mdpi.com/2073-4409/11/9/1464

“Deconstructing Sox2 Function in Brain Development and Disease”
by Sara Mercurio, Linda Serra, Miriam Pagin and Silvia K. Nicolis
Cells 2022, 11(10), 1604; https://doi.org/10.3390/cells11101604
Available online: https://www.mdpi.com/2073-4409/11/10/1604

“Evidence of Adult Features and Functions of Hepatocytes Differentiated from Human Induced Pluripotent Stem Cells and Self-Organized as Organoids”
by Antonietta Messina, Eléanor Luce, Nassima Benzoubir, Mattia Pasqua, Ulysse Pereira, Lydie Humbert, Thibaut Eguether, Dominique Rainteau, Jean-Charles Duclos-Vallée, Cécile Legallais et al.
Cells 2022, 11(3), 537; https://doi.org/10.3390/cells11030537
Available online: https://www.mdpi.com/2073-4409/11/3/537

“Batch Effects during Human Bone Marrow Stromal Cell Propagation Prevail Donor Variation and Culture Duration: Impact on Genotype, Phenotype and Function”
by Gabriele Brachtl, Rodolphe Poupardin, Sarah Hochmann, Anna Raninger, Karsten Jürchott, Mathias Streitz, Stephan Schlickeiser, Michaela Oeller, Martin Wolf, Katharina Schallmoser et al.
Cells 2022, 11(6), 946; https://doi.org/10.3390/cells11060946
Available online: https://www.mdpi.com/2073-4409/11/6/946

“Central Roles of STAT3-Mediated Signals in Onset and Development of Cancers: Tumorigenesis and Immunosurveillance”
by Shigeru Hashimoto, Ari Hashimoto, Ryuta Muromoto, Yuichi Kitai, Kenji Oritani and Tadashi Matsuda
Cells 2022, 11(16), 2618; https://doi.org/10.3390/cells11162618
Available online: https://www.mdpi.com/2073-4409/11/16/2618

“The Induced Pluripotent Stem Cells in Articular Cartilage Regeneration and Disease Modelling: Are We Ready for Their Clinical Use?”
by Michał S. Lach, Monika A. Rosochowicz, Magdalena Richter, Inga Jagiełło, Wiktoria M. Suchorska and Tomasz Trzeciak
Cells 2022, 11(3), 529; https://doi.org/10.3390/cells11030529
Available online: https://www.mdpi.com/2073-4409/11/3/529

“Valproic Acid-Induced CCN1 Promotes Osteogenic Differentiation by Increasing CCN1 Protein Stability through HDAC1 Inhibition in Tonsil-Derived Mesenchymal Stem Cells”
by Yeonsil Yu, Se-Young Oh, Ha Yeong Kim, Ji-Young Choi, Sangmee Ahn Jo and Inho Jo
Cells 2022, 11(3), 534; https://doi.org/10.3390/cells11030534
Available online: https://www.mdpi.com/2073-4409/11/3/534

“Regenerative Rehabilitation and Stem Cell Therapy Targeting Chronic Spinal Cord Injury: A Review of Preclinical Studies”
by Syoichi Tashiro, Masaya Nakamura and Hideyuki Okan
Cells 2022, 11(4), 685; https://doi.org/10.3390/cells11040685
Available online: https://www.mdpi.com/2073-4409/11/4/685

“Pre-Conditioning with IFN-γ and Hypoxia Enhances the Angiogenic Potential of iPSC-Derived MSC Secretome”
by Suya Wang, Felix Umrath, Wanjing Cen, António José Salgado, Siegmar Reinert and Dorothea Alexander
Cells 2022, 11(6), 988; https://doi.org/10.3390/cells11060988
Available online: https://www.mdpi.com/2073-4409/11/6/988

“Biomaterials and Extracellular Vesicle Delivery: Current Status, Applications and Challenges”
by Kasey S. Leung, Sajjad Shirazi, Lyndon F. Cooper and Sriram Ravindran
Cells 2022, 11(18), 2851; https://doi.org/10.3390/cells11182851
Available online: https://www.mdpi.com/2073-4409/11/18/2851

“Dermal Papilla Cell-Derived Extracellular Vesicles Increase Hair Inductive Gene Expression in Adipose Stem Cells via β-Catenin Activation”
by Taheruzzaman Kazi, Abir Nagata, Takatoshi Nakagawa, Takashi Matsuzaki and Shigeki Inui
Cells 2022, 11(2), 202; https://doi.org/10.3390/cells11020202
Available online: https://www.mdpi.com/2073-4409/11/2/202

“CRISPR/Cas9-Mediated Models of Retinitis Pigmentosa Reveal Differential Proliferative Response of Müller Cells between Xenopus laevis and Xenopus tropicalis
by Karine Parain, Sophie Lourdel, Alicia Donval, Albert Chesneau, Caroline Borday, Odile Bronchain, Morgane Locker and Muriel Perron
Cells 2022, 11(5), 807; https://doi.org/10.3390/cells11050807
Available online: https://www.mdpi.com/2073-4409/11/5/807

“Activation of the Renin–Angiotensin System Disrupts the Cytoskeletal Architecture of Human Urine-Derived Podocytes”
by Lars Erichsen, Chantelle Thimm, Martina Bohndorf, Md Shaifur Rahman, Wasco Wruck and James Adjaye
Cells 2022, 11(7), 1095; https://doi.org/10.3390/cells11071095
Available online: https://www.mdpi.com/2073-4409/11/7/1095

“The Potential Clinical Use of Stem/Progenitor Cells and Organoids in Liver Diseases”
by Christina Nikokiraki, Adriana Psaraki and Maria G. Roubelakis
Cells 2022, 11(9), 1410; https://doi.org/10.3390/cells11091410
Available online: https://www.mdpi.com/2073-4409/11/9/1410

“Universal or Personalized Mesenchymal Stem Cell Therapies: Impact of Age, Sex, and Biological Source”
by Diana M. Carp and Yun Liang
Cells 2022, 11(13), 2077; https://doi.org/10.3390/cells11132077
Available online: https://www.mdpi.com/2073-4409/11/13/2077

“Cerebral Organoids as an Experimental Platform for Human Neurogenomics”
by Tomasz J. Nowakowski and Sofie R. Salama
Cells 2022, 11(18), 2803; https://doi.org/10.3390/cells11182803
Available online: https://www.mdpi.com/2073-4409/11/18/2803

“Mesenchymal Stem Cell-Derived Extracellular Vesicles for Therapeutic Use and in Bioengineering Applications”
by Caroline McLaughlin, Pallab Datta, Yogendra P. Singh, Alexis Lo, Summer Horchler, Irina A. Elcheva, Ibrahim T. Ozbolat, Dino J. Ravnic and Srinivas V. Koduru
Cells 2022, 11(21), 3366; https://doi.org/10.3390/cells11213366
Available online: https://www.mdpi.com/2073-4409/11/21/3366

“Molecular Mechanisms and Clinical Application of Multipotent Stem Cells for Spinal Cord Injury”
by Michał Szymoniuk, Jakub Litak, Leon Sakwa, Aleksandra Dryla, Wojciech Zezuliński, Wojciech Czyżewski, Piotr Kamieniak and Tomasz Blicharski
Cells 2023, 12(1), 120; https://doi.org/10.3390/cells12010120
Available online: https://www.mdpi.com/2073-4409/12/1/120

“Generation of an hiPSC-Derived Co-Culture System to Assess the Effects of Neuroinflammation on Blood–Brain Barrier Integrity”
by Daniel Bull, Christophe Schweitzer, Colette Bichsel, Markus Britschgi and Simon Gutbier
Cells 2022, 11(3), 419; https://doi.org/10.3390/cells11030419
Available online: https://www.mdpi.com/2073-4409/11/3/419

“Extracellular Vesicles Derived from Primed Mesenchymal Stromal Cells Loaded on Biphasic Calcium Phosphate Biomaterial Exhibit Enhanced Macrophage Polarization”
by Neha Rana, Salwa Suliman, Niyaz Al-Sharabi and Kamal Mustafa
Cells 2022, 11(3), 470; https://doi.org/10.3390/cells11030470
Available online: https://www.mdpi.com/2073-4409/11/3/470

“Hematopoietic Cells from Pluripotent Stem Cells: Hope and Promise for the Treatment of Inherited Blood Disorders”
by Ilaria Rao, Laura Crisafulli, Marianna Paulis and Francesca Ficara
Cells 2022, 11(3), 557; https://doi.org/10.3390/cells11030557
Available online: https://www.mdpi.com/2073-4409/11/3/557

“Impaired p53-Mediated DNA Damage Response Contributes to Microcephaly in Nijmegen Breakage Syndrome Patient-Derived Cerebral Organoids”
by Soraia Martins, Lars Erichsen, Angeliki Datsi, Wasco Wruck, Wolfgang Goering, Eleftheria Chatzantonaki, Vanessa Cristina Meira de Amorim, Andrea Rossi, Krystyna H. Chrzanowska and James Adjaye
Cells 2022, 11(5), 802; https://doi.org/10.3390/cells11050802
Available online: https://www.mdpi.com/2073-4409/11/5/802

“Tet1 Suppresses p21 to Ensure Proper Cell Cycle Progression in Embryonic Stem Cells”
by Stephanie Chrysanthou, Julio C. Flores and Meelad M. Dawlaty
Cells 2022, 11(8), 1366; https://doi.org/10.3390/cells11081366
Available online: https://www.mdpi.com/2073-4409/11/8/1366

“Cell Aggregate Assembly through Microengineering for Functional Tissue Emergence”
by Gozde Eke, Laurence Vaysse, Xi Yao, Mélanie Escudero, Audrey Carrière, Emmanuelle Trevisiol, Christophe Vieu, Christian Dani, Louis Casteilla and Laurent Malaquin
Cells 2022, 11(9), 1394; https://doi.org/10.3390/cells11091394
Available online: https://www.mdpi.com/2073-4409/11/9/1394

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