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NeuroSci, Volume 6, Issue 1

2025 March - 26 articles

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Articles (26)

  • Systematic Review
  • Open Access
2 Citations
5,836 Views
12 Pages

Near-Infrared Stimulation in Psychiatry Disorders: A Systematic Review of Efficacy and Biological Mechanisms

  • Joanna Woźniak,
  • Michał Pazdrak,
  • Ada Domanasiewicz and
  • Jakub Kaźmierski

Background: Photobiomodulation (PBM), also referred to as low-level light therapy (LLLT), is an emerging non-pharmacological approach. This treatment is considered low-risk, cost-effective, and non-invasive, utilizing near-infrared light (NIR). The p...

  • Article
  • Open Access
1 Citations
1,452 Views
14 Pages

Carbamoylated Erythropoietin Rescues Autism-Relevant Social Deficits in BALB/cJ Mice

  • Amaya L. Street,
  • Vedant P. Thakkar,
  • Sean W. Lemke,
  • Liza M. Schoenbeck,
  • Kevin M. Schumacher,
  • Monica Sathyanesan,
  • Samuel S. Newton and
  • Alexander D. Kloth

Autism spectrum disorder (ASD) is a neurodevelopmental disorder that affects over 2% of the population worldwide and is characterized by repetitive behaviors, restricted areas of interest, deficits in social communication, and high levels of anxiety....

  • Article
  • Open Access
1,485 Views
9 Pages

Parkinson’s disease (PD) is a progressive neurodegenerative disorder characterized by the selective loss of dopaminergic (DA) neurons in the midbrain. While dopamine precursor levodopa and D2 receptor agonists are commonly used to alleviate PD...

  • Systematic Review
  • Open Access
6 Citations
10,662 Views
12 Pages

The Influence of Noise Exposure on Cognitive Function in Children and Adolescents: A Meta-Analysis

  • David Fernández-Quezada,
  • Diana Emilia Martínez-Fernández,
  • Ileana Fuentes,
  • Joaquín García-Estrada and
  • Sonia Luquin

Environmental noise has been repeatedly linked to negative effects on cognitive functioning among children and adolescents. This research sought to systematically assess studies investigating the relationship between noise exposure and cognitive outc...

  • Review
  • Open Access
8 Citations
5,003 Views
17 Pages

The Connection Between Oxidative Stress, Mitochondrial Dysfunction, Iron Metabolism and Microglia in Multiple Sclerosis: A Narrative Review

  • Simonida Delic,
  • Svetlana Miletic Drakulic,
  • Milos Stepovic,
  • Jovana Milosavljevic,
  • Marija Kovacevic Dimitrijevic,
  • Kristijan Jovanovic,
  • Ivona Marinkovic,
  • Melanija Tepavcevic,
  • Nikoleta Janicijevic and
  • Maja Vulovic
  • + 2 authors

In recent years, in the pathogenesis of multiple sclerosis, emphasis has been placed on mitochondrial processes that influence the onset of the disease. Oxidative stress would be one of the consequences of mitochondrial dysfunction, and its impact on...

  • Systematic Review
  • Open Access
4,265 Views
16 Pages

Association Between Stroke and Traumatic Brain Injury: A Systematic Review and Meta-Analysis

  • Mohammed Maan Al-Salihi,
  • Maryam Sabah Al-Jebur,
  • Ahmed Abd Elazim,
  • Ram Saha,
  • Ahmed Saleh,
  • Farhan Siddiq,
  • Ali Ayyad and
  • Adnan I. Qureshi

Background: Stroke and traumatic brain injury (TBI) represent two major health concerns worldwide. There is growing evidence suggesting a potential association between TBI and stroke. In this systematic review and meta-analysis, we aim to explore the...

  • Article
  • Open Access
2 Citations
3,102 Views
13 Pages

Impaired Regulation of Emotion in Bipolar I Disorder: Behavioral and Neurophysiological Signatures

  • Mathilde Carminati,
  • Frédéric Isel,
  • Josselin Houenou,
  • Michèle Wessa and
  • Chantal Henry

People with bipolar disorder (BD) present with mood instability resulting from more frequent and intense emotions in response to environmental conditions relative to healthy subjects. The aim of this study was to investigate the time course of emotio...

  • Article
  • Open Access
1 Citations
3,457 Views
17 Pages

Liposomal Lactoferrin Reduces Brain Neuroinflammation in Rats and Alleviates Jetlag and Improves Sleep Quality After Long-Haul Travel

  • Shoko Uesaki,
  • Masanori Yamato,
  • Atsushi Ishikado,
  • Yutaka Suekawa,
  • Yasuhisa Tamura and
  • Yosky Kataoka

Insufficient sleep and circadian misalignment increase inflammatory agents. This triggers neuroinflammation and can result in health issues including depression, dementia, lifestyle-related diseases, and industrial accidents. Lactoferrin (LF) confers...

  • Technical Note
  • Open Access
1 Citations
2,283 Views
19 Pages

25 February 2025

(1) Background: Multiple lumbar spinal stenosis (LSS) is a degenerative disease that is increasingly prevalent with global aging. Multilevel fusion surgery is burdensome to perform in elderly patients, especially with osteoporosis and underlying dise...

  • Article
  • Open Access
2 Citations
1,419 Views
12 Pages

Pain Pressure Threshold as a Non-Linear Marker of Neural Adaptation in Amputees: Evidence from the DEFINE Cohort

  • Marta Imamura,
  • Anna Carolyna Gianlorenço,
  • Guilherme J. M. Lacerda,
  • Linamara Rizzo Battistella and
  • Felipe Fregni

18 February 2025

Background: Amputation poses significant physical, psychological, and emotional challenges, with chronic pain being one of the most debilitating outcomes. Pain Pressure Threshold (PPT), a measure of nociceptive sensitivity, is a valuable tool for ass...

  • Article
  • Open Access
4 Citations
7,143 Views
12 Pages

Trends and Disparities in Alzheimer’s Disease Mortality in the United States: The Impact of COVID-19

  • Jasleen Chaddha,
  • Eli Blaney,
  • Ali Al-Salahat,
  • Amna Noor,
  • Taylor Billion,
  • Yu-Ting Chen,
  • Abubakar Tauseef,
  • Akshat Sood and
  • Ali Bin Abdul Jabbar

14 February 2025

Background: Alzheimer’s disease (AD) is the fifth leading cause of death for Americans older than 65. Though fluctuations have been noticed over the past two decades, the mortality of Alzheimer’s patients increased considerably during the...

  • Article
  • Open Access
2,135 Views
14 Pages

10 February 2025

Background: Fibromyalgia syndrome (FMS), a chronic pain syndrome affecting 0.2–6.6% of the general population, is known for its challenging diagnosis and treatment. The known dysregulation in the Endogenous Pain Modulatory System (EPMS) charact...

  • Article
  • Open Access
3 Citations
1,537 Views
13 Pages

8 February 2025

Objective: As outlined in our previous study, this study aims to investigate the role of body mass index (BMI) as an effect modifier in the relationship between conditioned pain modulation (CPM) and clinical outcomes, including depression, quality of...

  • Article
  • Open Access
1,946 Views
18 Pages

Contextual Influence on Pattern Separation During Encoding

  • Laura García-Rueda,
  • Claudia Poch,
  • Joaquín Macedo-Pascual and
  • Pablo Campo

6 February 2025

Pattern separation is considered a crucial process that allows us to distinguish among the highly similar and overlapping experiences that constitute our episodic memory. Not only do different episodes share common features, but it is often the case...

  • Article
  • Open Access
3 Citations
4,074 Views
11 Pages

Stress-Induced Hyperglycemia Predicts Poor Outcomes in Primary Intracerebral Hemorrhage Patients

  • Kevin Gilotra,
  • Jade Basem,
  • Melissa Janssen,
  • Sujith Swarna,
  • Racheed Mani,
  • Benny Ren and
  • Reza Dashti

2 February 2025

Introduction: The current literature suggests hyperglycemia can predict poor outcomes in patients with primary intracerebral hemorrhage (ICH). Chronic hyperglycemia is seen in patients with pre-existing diabetes (DM); however, acute hyperglycemia in...

  • Systematic Review
  • Open Access
2 Citations
6,918 Views
17 Pages

1 February 2025

Alzheimer’s disease is the most common form of dementia. Benzodiazepines are the most widely used pharmacological class in the treatment of insomnia and other sleep disorders. Some literature suggests that the chronic use of benzodiazepines is...

  • Article
  • Open Access
1 Citations
2,149 Views
16 Pages

Employment and Its Determinants for Spinal Cord Injury Population in Romania

  • Camelia Florentina Lascu,
  • Daiana Popa,
  • Camelia Liana Buhaș,
  • Florica Voiţă-Mekereş,
  • Florina Ligia Popa,
  • Matei Teodorescu,
  • Georgiana Albina Căiță,
  • Gheorghe Szilagyi,
  • Andrada Florina Schwarz-Madar and
  • Călin Tudor Hozan
  • + 1 author

1 February 2025

This study investigates employment rates and their determinants among individuals with spinal cord injury (SCI) in Romania using data from the Romanian National Spinal Cord Injury Survey (RO-InSCI), part of the International Spinal Cord Injury (InSCI...

  • Article
  • Open Access
2,378 Views
11 Pages

28 January 2025

Hypoxia due to stroke is a major cause of neuronal damage, leading to loss of cognition and other brain functions. Sevoflurane preconditioning improves recovery after hypoxia. Hypoxia interferes with protein expression at the translational level; how...

  • Article
  • Open Access
3 Citations
2,968 Views
30 Pages

Distinguishing Early from Late Mild Cognitive Impairment Using Magnetic Resonance Free-Water Diffusion Tensor Imaging

  • Maurizio Bergamino,
  • Molly M. McElvogue,
  • Ashley M. Stokes and
  • Alzheimer’s Disease Neuroimaging Initiative

18 January 2025

Mild Cognitive Impairment (MCI) is a transitional stage between normal aging and Alzheimer’s disease. Differentiating early MCI (EMCI) from late MCI (LMCI) is crucial for early diagnosis and intervention. This study used free-water diffusion te...

  • Article
  • Open Access
1 Citations
5,831 Views
12 Pages

16 January 2025

Background: Hypokinetic dysarthria is a speech disorder observed in almost 90% of PD patients that can appear at any stage of the disease, usually worsening as the disease progresses. Today, speech therapy intervention in PD is seen as a possible the...

  • Article
  • Open Access
1 Citations
3,959 Views
15 Pages

Trends and Disparities in Parkinson’s Disease Mortality in the United States with Predictions Using Machine Learning

  • Henry Weresh,
  • Kallin Hermann,
  • Ali Al-Salahat,
  • Amna Noor,
  • Taylor Billion,
  • Yu-Ting Chen,
  • Abubakar Tauseef and
  • Ali Bin Abdul Jabbar

15 January 2025

Background: Parkinson’s disease (PD) is a progressive neurodegenerative condition characterized by the degradation of dopaminergic pathways in the brain. As the population in the United States continues to age, it is essential to understand the...

  • Review
  • Open Access
1 Citations
3,038 Views
16 Pages

13 January 2025

Dementia, including Alzheimer’s disease (AD) and frontotemporal dementia (FTD), presents critical challenges for correctional systems, particularly as global populations age. AD, affecting 60–80% of dementia cases, primarily impairs memor...

  • Article
  • Open Access
4 Citations
3,907 Views
17 Pages

Multiple sclerosis (MS) is a multifactorial disease, with diet and lifestyle playing an important role in its development. The Mediterranean diet has been considered to be particularly beneficial for MS patients. The aim of the present study was to i...

  • Review
  • Open Access
3 Citations
4,189 Views
11 Pages

This review emphasises the importance of the cardiovascular response to facial cooling (FC) and breath holding in both sexes. The trigemino-cardiac reflex, triggered by FC, reduces heart rate (HR) and constricts blood vessels. When combined with brea...

  • Article
  • Open Access
1 Citations
1,479 Views
11 Pages

Visual Noise Mask for Human Point-Light Displays: A Coding-Free Approach

  • Catarina Carvalho Senra,
  • Adriana Conceição Soares Sampaio and
  • Olivia Morgan Lapenta

Human point-light displays consist of luminous dots representing human articulations, thus depicting actions without pictorial information. These stimuli are widely used in action recognition experiments. Because humans excel in decoding human motion...

  • Case Report
  • Open Access
1 Citations
3,053 Views
8 Pages

30 December 2024

Background: Acute disseminated encephalomyelitis (ADEM) is a rare, immune-mediated inflammatory disorder of the central nervous system (CNS), typically characterized by the acute onset of multifocal demyelination. The pathogenesis of ADEM remains unc...

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NeuroSci - ISSN 2673-4087