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Organics, Volume 6, Issue 2

2025 June - 15 articles

Cover Story: Aniline is one of the most representative molecules of the intrinsic polarity of chemistry: the first artificial dyes were obtained from it, with a decisive push towards the industrial revolution but also with negative repercussions on the health of workers. It has exerted a great influence on fashion and art, becoming the symbol of an era of great innovations, but also of contradictions and social conflicts. Today, it still plays a key role in various sectors, including the production of inks, the synthesis of drugs, and the design of smart textiles. Its history and its chemistry are extremely significant for a broad-ranging educational approach. View this paper
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Articles (15)

  • Article
  • Open Access
1 Citations
1,836 Views
18 Pages

Tannins from Acacia mearnsii De Wild as a Sustainable Alternative for the Development of Latent Fingerprints

  • Danielle Tapia Bueno,
  • Amanda Fonseca Leitzke,
  • Rayane Braga Martins,
  • Daisa Hakbart Bonemann,
  • Emanuel Gomes Bertizzolo,
  • Gabrielly Quartieri Sejanes,
  • Juliana Porciúncula da Silva,
  • Lucas Minghini Gonçalves,
  • Neftali Lenin Villarreal Carreno and
  • Claudio Martin Pereira de Pereira

18 June 2025

Papilloscopy, the science of human identification through fingerprints, has seen notable advancements in developing less toxic latent fingerprint developers (LFDs), especially from natural feedstock. Tannins, the second most abundant natural polyphen...

  • Article
  • Open Access
1 Citations
1,156 Views
10 Pages

A Study of the Inclusion Complex Formed Between Cucurbit[8]uril and N,4-Di(pyridinyl)benzamide Derivative

  • Zhikang Wang,
  • Mingjie Yang,
  • Weibo Yang,
  • Zhongzheng Gao,
  • Hui Zhao,
  • Gang Wei and
  • Jifu Sun

17 June 2025

The interaction between cucurbit[8]uril (Q[8]) and the guest 1-methyl-4-(4-(1-methylpyridin-1-ium-4-yl)benzamido)pyridin-1-ium (PB2+) has been thoroughly investigated. Multiple techniques were employed, including 1H NMR spectroscopy, mass spectrometr...

  • Article
  • Open Access
1,201 Views
11 Pages

5 June 2025

A macrocyclic receptor based on azopyrrole and polyether was synthesized, and its structure was characterized by NMR (1H and 13C), HRMS and X-ray crystallography. In the solid state, the macrocyclic molecules could bind methanol through a pair of N-H...

  • Article
  • Open Access
1,010 Views
9 Pages

Efficient Synthesis of Novel 10R-Pyrido[4,3-a]Phenazines, Including the Series Progenitor

  • Artem P. Ermolenko,
  • Diana Y. Pobedinskaya,
  • Elena K. Avakyan,
  • Anastasia A. Borovleva,
  • Alexander N. Larin,
  • Ivan V. Borovlev and
  • Oleg P. Demidov

3 June 2025

A series of previously poorly studied heterocyclic compounds, 10R-pyrido[4,3-a]phenazines, including the previously unknown parent compound, has been synthesized. The proposed synthetic approach is remarkable for its simplicity, due to the ease of th...

  • Review
  • Open Access
3,108 Views
21 Pages

Beyond Peptides and Peptidomimetics: Natural Heteroaromatic Amino Acids in the Synthesis of Fused Heterocyclic Frameworks for Bioactive Agents

  • Isis Apolo Silveira de Borba,
  • Jamile Buligon Peripolli,
  • Angélica Rocha Joaquim and
  • Fernando Fumagalli

21 May 2025

Heterocycle cores are widely used in medicinal chemistry for developing bioactive compounds. In this scenario, using cheap and accessible starting material to build these heterocycles is desirable to obtain new drug candidates for cost-efficient proc...

  • Review
  • Open Access
2 Citations
3,086 Views
22 Pages

Advances in Green Synthesis and Photo-/Electrocatalytic Applications of Zirconium-Based MOFs: A Review

  • Tian Zhao,
  • Shilin Peng,
  • Jiangrong Yu,
  • Jiayao Chen,
  • Fuli Luo,
  • Pengcheng Xiao,
  • Saiqun Nie and
  • Yi Chen

9 May 2025

Metal–organic frameworks (MOFs), particularly zirconium-based frameworks (Zr-MOFs), have gained significant attention in recent years due to their unique structural and functional properties. This review focuses on eco-friendly synthetic method...

  • Article
  • Open Access
1,562 Views
24 Pages

Adsorption of Methylene Blue Dye onto Various Marine Sediments and Seagrass Biomass of Posidonia oceanica Species: Kinetics and Equilibrium Studies

  • Maria C. Vagi,
  • Andreas S. Petsas,
  • Dionysia Dimitropoulou,
  • Melpomeni Leventelli and
  • Anastasia D. Nikolaou

6 May 2025

This study concerns the investigation of the sorption and desorption phenomena of the organic dye methylene blue (MB) on three different marine sediments and non-living biomass of the seagrass species Posidonia oceanica. All tested adsorbents were of...

  • Review
  • Open Access
1 Citations
4,038 Views
19 Pages

1 May 2025

In the chemical education field, the Johnstone’s triangle represents three learning levels (symbolic, macroscopic, and molecular) needed for students. Afterwards, Mahaffy suggested a tetrahedron model based on this triangle, where the top repre...

  • Review
  • Open Access
5 Citations
3,913 Views
18 Pages

Use and Roles of Tannins in Polysaccharide-Based Bioplastics and Biocomposites

  • Carlo Santulli,
  • Serena Gabrielli and
  • Graziella Roselli

1 May 2025

Most bioplastics are based on polysaccharides, which are either synthesized from a variously sourced monomer or extracted from some biomass waste. In many cases, some lignocellulosic fibers are then added to the obtained bioplastics to form biocompos...

  • Article
  • Open Access
2,774 Views
18 Pages

Synthesis of Bipyridine Ether-Type Bifunctional Precursors

  • Bálint Jávor,
  • Antal Agárdi,
  • Péter Kisfaludi,
  • Barnabás Frigyes,
  • Márton Temesvári,
  • Panna Vezse,
  • Tünde Tóth,
  • Péter Huszthy and
  • Ádám Golcs

10 April 2025

Bipyridine ethers are commonly occurring structural motifs in supramolecular chemistry. The herein reported efforts aim to extend the synthetic platform of bipyridino-precursors with new bifunctional intermediates and to improve some previously repor...

  • Article
  • Open Access
2 Citations
1,658 Views
13 Pages

Small Deviations in Geometries Affect Detonation Velocities and Pressures of Nitroaromatic Molecules

  • Danijela S. Kretić,
  • Marija I. Maslarević and
  • Dušan Ž. Veljković

9 April 2025

Understanding the factors that affect the detonation performance of high-energy molecules (HEMs) is crucial for the design of novel explosives and fuels with desirable characteristics. While molecular factors, such as the presence of specific functio...

  • Review
  • Open Access
11 Citations
12,041 Views
49 Pages

An Overview of Quinolones as Potential Drugs: Synthesis, Reactivity and Biological Activities

  • Ayoub El-mrabet,
  • Amal Haoudi,
  • Youssef Kandri-Rodi and
  • Ahmed Mazzah

3 April 2025

Quinolones represent one of the largest classes of synthetic antibiotics used in both human and veterinary medicine. Since the discovery of nalidixic acid, a substantial body of research has been carried out on quinolones, resulting in the synthesis...

  • Article
  • Open Access
2,426 Views
11 Pages

Synthesis of Indole-Based Derivatives Containing Ammonium Salts, Diamines and Aminoureas for Organocatalysis

  • Marcello Casertano,
  • Brian G. Kelly,
  • Malachi W. Gillick-Healy,
  • Paolo Grieco and
  • Mauro F. A. Adamo

2 April 2025

Indole heterocycles have an established reactivity, and these compounds are H-bond donors via a peculiar non-basic NH. However, the indole core has been scarcely employed in organocatalysis, with only a few examples relevant to electrophilic halogena...

  • Article
  • Open Access
1,383 Views
9 Pages

Optimized Synthesis of Dinitrochalcones via Ultrasonic Bath in a Cyclohexane–Methanol Solvent System

  • Alam Yair Hidalgo,
  • Quirino Torres-Sauret,
  • Carlos Ernesto Lobato-García,
  • Erika Madeleyne Ramos-Rivera,
  • Luis Fernando Roa de la Fuente,
  • Abraham Gómez-Rivera,
  • Miguel Ángel Vilchis-Reyes,
  • Erika Alarcón-Matus,
  • Oswaldo Hernández-Abreu and
  • Nancy Romero-Ceronio

1 April 2025

This study describes the efficient synthesis of five dinitrochalcones (DNCHs) using an ultrasonic bath as an unconventional method to improve reaction yields and reduce reaction times. The Claisen–Schmidt condensation of nitroacetophenones and...

  • Article
  • Open Access
1 Citations
3,452 Views
26 Pages

Synthesis and In Silico Evaluation of GABA, Pregabalin and Baclofen N-Heterocyclic Analogues as GABAB Receptor Agonists

  • Zuleyma Martínez-Campos,
  • Luis Eduardo Hernandez-Dominguez,
  • Fatima Romero-Rivera,
  • Diana López-López,
  • María Vicky Corona-González,
  • Susana T. López-Cortina,
  • Francisco José Palacios-Can,
  • Rodrigo Said Razo-Hernández and
  • Mario Fernández-Zertuche

24 March 2025

γ-amino butyric acid (GABA) is an inhibitory neurotransmitter whose deficiency has been associated with various neurological disorders. However, its low liposolubility limits its use as a supplement. Thus, multiple investigations have focused o...

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Organics - ISSN 2673-401X