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Gastrointestinal Disorders, Volume 2, Issue 4

December 2020 - 13 articles

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Articles (13)

  • Review
  • Open Access
6 Citations
3,904 Views
12 Pages

Assessment of Current Gene Therapy Practices in Hepatocellular Carcinoma

  • Bryan Mckiver,
  • Mohamad Imad Damaj and
  • Devanand Sarkar

Hepatocellular carcinoma (HCC) is the most common form of primary liver cancer and the fifth most common cancer worldwide. HCC is recognized as the fourth most common cause of cancer related deaths worldwide due to the lack of effective early diagnos...

  • Article
  • Open Access
9 Citations
4,974 Views
13 Pages

Ureteral Stent and Percutaneous Nephrostomy in Managing Malignant Ureteric Obstruction of Gastrointestinal Origin: A 10 Years’ Experience

  • Elisa De Lorenzis,
  • Elena Lievore,
  • Matteo Turetti,
  • Andrea Gallioli,
  • Barbara Galassi,
  • Luca Boeri and
  • Emanuele Montanari

Background: Malignant ureteral obstruction (MUO) is variable in presentation and there is no consensus on its management, especially when caused by gastrointestinal (GI) malignancies. Our aim was to describe our experience with this oncological compl...

  • Brief Report
  • Open Access
3 Citations
4,621 Views
8 Pages

Utility of Direct Fast Scarlet Staining in the Histopathological Diagnosis of Eosinophilic Esophagitis: A Short Report

  • Takuji Tanaka,
  • Naoki Watanabe,
  • Tomohiro Kato,
  • Ryogo Aoki,
  • Tomio Ogiso,
  • Akihiko Sugiyama and
  • Eiichi Tomita

Eosinophilic esophagitis (EoE), an atopic disease of the esophagus, has become increasingly recognized over the last 15 years. The epidemiology of EoE has now been reported from many countries around the world. While the clinical diagnosis of this di...

  • Review
  • Open Access
3 Citations
5,893 Views
25 Pages

The pandemic spread of obesity and type 2 diabetes is a serious health problem that cannot be contained with common therapies. At present, the most effective therapeutic tool is metabolic surgery, which substantially modifies the gastrointestinal ana...

  • Review
  • Open Access
3 Citations
4,371 Views
8 Pages

Per Oral Pyloromyotomy for Gastroparesis: A Systematic Review of the Current Literature and Future Recommendations

  • Luis O. Chavez,
  • Gian Galura,
  • Alejandro Robles,
  • Marco A. Bustamante-Bernal and
  • Richard McCallum

Background: Gastric per oral endoscopic myotomy (GPOEM) was developed as a therapeutic option for gastroparesis after the pylorus was identified as a key target for gastroparesis management. This study includes a systematic literature review of studi...

  • Article
  • Open Access
1 Citations
8,523 Views
7 Pages

Plummer-Vinson Syndrome: A Time for Redefinition and New Perspectives

  • J. Daniel Herlihy,
  • Vismay Badhiwala,
  • Osvaldo Padilla,
  • Jesus Diaz and
  • Richard McCallum

Plummer-Vinson syndrome (PVS) is defined by the classic triad of dysphagia, esophageal web, and iron deficiency. It is a rare entity that remains poorly understood, and we describe our experience in diagnosing and management. Treatment for patients w...

  • Article
  • Open Access
3,763 Views
11 Pages

Tumor Regression in Lymph Node Metastases of Esophageal Adenocarcinomas after Neoadjuvant Therapy

  • Marek Osecky,
  • Dino Kröll,
  • Marcus Feith,
  • Daniel Reim,
  • Bastian Dislich,
  • Karen Becker and
  • Rupert Langer

Tumor regression following neoadjuvant treatment can be observed in lymph node (LN) metastases similar to the primary tumor in esophageal adenocarcinomas (EAC). We evaluated the prognostic significance of tumor regression in LN metastases of locally...

  • Brief Report
  • Open Access
2,814 Views
7 Pages

The Clinical Impact of MicroRNA-21 in Low Rectal Cancer Treated with High-Dose Chemoradiotherapy in the Organ Preserving Setting

  • Caroline Brenner Thomsen,
  • Rikke Fredslund Andersen,
  • Lars Henrik Jensen,
  • Anders Jakobsen and
  • Torben Frøstrup Hansen

Background: Organ preservation in the treatment of rectal cancer has seen an increase in interest. Clinical complete response (cCR) after high-dose chemoradiotherapy (CRT) allows for non-surgical management (NSM), but the selection of patients is cha...

  • Article
  • Open Access
4 Citations
4,371 Views
12 Pages

Allopurinol Suppresses Azoxymethane-Induced Colorectal Tumorigenesis in C57BL/KsJ-db/db Mice

  • Junichi Kato,
  • Yohei Shirakami,
  • Kimihiro Yamaguchi,
  • Taku Mizutani,
  • Takayasu Ideta,
  • Hiroshi Nakamura,
  • Soranobu Ninomiya,
  • Masaya Kubota,
  • Hiroyasu Sakai and
  • Takashi Ibuka
  • + 2 authors

Obesity and related metabolic disorders, including chronic inflammation and enhanced oxidative stress, are closely associated with the development and progression of colorectal cancer. Previous epidemiological studies have demonstrated that increased...

  • Review
  • Open Access
2 Citations
4,395 Views
13 Pages

Making Decisions about Dietary Therapy in Inflammatory Bowel Disease

  • Sydney Solomon,
  • Eunie Park and
  • Joseph A. Picoraro

Treatment for inflammatory bowel disease (IBD) deserves an informed shared decision-making process between patient and doctor. IBD spans a spectrum of phenotypes that impact each patient uniquely. While treatment has primarily consisted of medical or...

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Gastrointest. Disord. - ISSN 2624-5647Creative Common CC BY license