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  • Review
  • Open Access
8 Citations
21,771 Views
12 Pages

Metoclopramide in Gastroparesis: Its Mechanism of Action and Safety Profile

  • M Ammar Kalas,
  • Bhavi Trivedi,
  • Mutaz Kalas,
  • Luis O. Chavez and
  • Richard W. McCallum

Metoclopramide has been the cornerstone of gastroparesis management for the past 40 years as it is the only FDA-approved medication for gastroparesis. Other medications such as erythromycin and domperidone have been used off-label with variable effic...

  • Review
  • Open Access
17 Citations
20,582 Views
15 Pages

Impact of Probiotics and Prebiotics on Gut Microbiome and Hormonal Regulation

  • Jelina Basnet,
  • Manar A. Eissa,
  • Licy L. Yanes Cardozo,
  • Damian G. Romero and
  • Samar Rezq

27 September 2024

The gut microbiome plays a crucial role in human health by influencing various physiological functions through complex interactions with the endocrine system. These interactions involve the production of metabolites, signaling molecules, and direct c...

  • Review
  • Open Access
16 Citations
18,990 Views
12 Pages

Evaluation and Management of Pediatric Feeding Disorder

  • Rajmohan Dharmaraj,
  • Rasha Elmaoued,
  • Razan Alkhouri,
  • Pankaj Vohra and
  • Ricardo O. Castillo

Feeding disorders are increasingly common in children, especially as medical advancements improve the life expectancy of children born with prematurity and complex medical conditions. The most common symptoms include malnutrition, refusal to eat and...

  • Article
  • Open Access
18,693 Views
14 Pages

The Efficacy of a Combination of Milk Thistle, Artichoke, and Green Tea in the Treatment of Biliary Sludge: An Interventional Prospective Open Study

  • Angela Saviano,
  • Ida Sicilia,
  • Alessio Migneco,
  • Carmine Petruzziello,
  • Mattia Brigida,
  • Marcello Candelli,
  • Francesco Franceschi and
  • Veronica Ojetti

Background: In Western countries, 10–20% of adults have gallstones, of which about 1–3% of patients are symptomatic for biliary colic. The treatment with ursodeoxycholic acid is debated. Silymarin is emerging nowadays as a natural substan...

  • Review
  • Open Access
21 Citations
18,456 Views
25 Pages

Main Disorders of Gastrointestinal Tract in Older People: An Overview

  • Antonella Gallo,
  • Simona Pellegrino,
  • Erika Pero,
  • Maria Chiara Agnitelli,
  • Caterina Parlangeli,
  • Francesco Landi and
  • Massimo Montalto

From a physiological standpoint, aging is a progressive reduction in each organ system’s capacity to maintain homeostasis in the face of illness or stressors. With advancing age, gastrointestinal (GI) symptoms and signs may increase, not only d...

  • Review
  • Open Access
25 Citations
17,457 Views
23 Pages

Microbiome-Driven Therapeutics: From Gut Health to Precision Medicine

  • Muneer Oladipupo Yaqub,
  • Aashika Jain,
  • Chinedu Eucharia Joseph and
  • Lekshmi K. Edison

The human microbiome, a complex ecosystem of microorganisms residing in and on the body, plays a pivotal role in the regulation of a wide range of physiological processes, including digestion, immune responses, and metabolic functions. In recent year...

  • Review
  • Open Access
5 Citations
15,525 Views
23 Pages

Comprehensive Review of Acute Pancreatitis Pain Syndrome

  • Jacob Beiriger,
  • Adnan Khan,
  • Brian Yan,
  • Heather Ross,
  • Makala Wang,
  • Michael Carducci,
  • Natalia Salinas Parra,
  • Salil Chowdhury,
  • Ryan Erwin and
  • Paul Forrest
  • + 2 authors

Pancreatitis is a condition that causes inflammation in the pancreas, an organ located behind the stomach. This condition often presents as neuropathic, inflammatory, and/or visceral pain. Acute pancreatitis is typically characterized by sudden and s...

  • Review
  • Open Access
1 Citations
14,589 Views
31 Pages

Gastroesophageal reflux disease (GERD) is a common chronic gastrointestinal disorder that greatly influences patients’ quality of life and represents a growing public health concern. Characterized by typical and atypical symptoms, GERD encompas...

  • Article
  • Open Access
1 Citations
12,987 Views
11 Pages

Chronic Kidney Disease Linked to Higher Incidence of Gastric Diseases

  • Xiaoliang Wang,
  • Zachary Wright,
  • Jiayan Wang,
  • Wesam M. Frandah and
  • Gengqing Song

This study aimed to investigate the relationship between chronic kidney disease (CKD) and different gastric diseases by conducting a population-based retrospective analysis using National Inpatient Sample (NIS) data. A total of 7,159,694 patients dia...

  • Review
  • Open Access
1 Citations
12,695 Views
10 Pages

Risk of Hemorrhoidal Bleeding in Patients Treated with Direct Oral Anticoagulants (DOACs)

  • Carmine Petruzziello,
  • Angela Saviano,
  • Mattia Brigida,
  • Alessio Migneco,
  • Luca Luigi Manetti,
  • Marcello Candelli and
  • Veronica Ojetti

(1) Background: Lower gastrointestinal bleeding (LGIB) accounts for 20% of all gastrointestinal bleeds. LGBI originates in the colon, rectum, and anus, mainly in patients who are receiving antiaggregant or anticoagulant treatment. The major causes ar...

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Gastrointest. Disord. - ISSN 2624-5647Creative Common CC BY license