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Proceedings 2017, 1(10), 1055;

Analysis of the Cytotoxic Effects of Eryngium billardieri Delar. Extracts on MCF7 Cell Line

Department of Pharmacognosy, Faculty of Pharmacy, Erciyes University, Melikgazi 38030, Turkey
Department of Biology Program of Botany, Faculty of Sciences, Selcuk University, Selçuklu 42250, Turkey
Presented at the 2nd International Conference on Natural Products for Cancer Prevention and Therapy, Kayseri, Turkey, 8–11 November 2017.
Author to whom correspondence should be addressed.
Published: 14 November 2017
PDF [143 KB, uploaded 14 November 2017]


The Apiaceae (previously known as the Umbelliferae) is one of the largest plant families in the world. This family comprises approximately 450 genera and 3700 species worldwide. The members of this family are well known as vegetables, culinary and medicinal plants. Members of Apiaceae possess various compounds with many biological activities. Some of the main properties are ability to induce apoptosis, antibacterial, hepatoprotective, vaso-relaxant, cyclooxygenase inhibitory and antitumor activities. In this study, 70% methanol extract prepared from the aerial parts of Eryngium billardieri, which belongs to Apiaceae family, and ethyl acetate, n-butanol fractions obtained from this extract were investigated by MTT method for cytotoxic effect on MCF7 (human breast cancer cell line) cell line. In result, the methanol extract was found more cytotoxic than fractions with 99.50 µg/mL IC50 value on MCF7 cell line.
Keywords: Eryngium billardieri; Apiaceae; cytotoxicity; MCF7 Eryngium billardieri; Apiaceae; cytotoxicity; MCF7
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited (CC BY 4.0).

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Paşayeva, L.; Köngül, E.; Geylan, R.; Karatoprak, G.Ş.; Tugay, O. Analysis of the Cytotoxic Effects of Eryngium billardieri Delar. Extracts on MCF7 Cell Line. Proceedings 2017, 1, 1055.

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