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Tropical Medicine and Infectious Disease, Volume 9, Issue 7

July 2024 - 28 articles

Cover Story: A difficult disease to diagnose, leptospirosis has a wide spectrum of clinical presentations, including life-threatening ones. Fresh water exposure coupled with skin injury or immersion can lead to disease, which puts flood victims, agricultural workers, military members, and recreational tourists at risk. Climate change should increase disease incidence, suggesting many people at risk would benefit from preventive measures such as pre- or post-exposure antibiotic chemoprophylaxis. Eight clinical trials and three meta-analyses have evaluated prophylaxis and failed to show a substantial benefit. Our review assessed strengths and weaknesses of previous trials and described flaws in trial design or conduct. Based on our analysis, we suggest how future trials may be better constructed to answer this important question. View this paper
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Articles (28)

  • Review
  • Open Access
22 Citations
5,258 Views
25 Pages

An Update on the Entomology, Virology, Pathogenesis, and Epidemiology Status of West Nile and Dengue Viruses in Europe (2018–2023)

  • Federica Frasca,
  • Leonardo Sorrentino,
  • Matteo Fracella,
  • Alessandra D’Auria,
  • Eleonora Coratti,
  • Luca Maddaloni,
  • Ginevra Bugani,
  • Massimo Gentile,
  • Alessandra Pierangeli and
  • Gabriella d’Ettorre
  • + 1 author

In recent decades, increases in temperature and tropical rainfall have facilitated the spread of mosquito species into temperate zones. Mosquitoes are vectors for many viruses, including West Nile virus (WNV) and dengue virus (DENV), and pose a serio...

  • Brief Report
  • Open Access
1 Citations
1,631 Views
4 Pages

Impact on Aedes aegypti Mosquitoes Exposed to Honey-Impregnated Flinders Technology Associates (FTA®) Cards

  • Amandine Guidez,
  • Albin Fontaine,
  • Arnaud Cannet,
  • Isabelle Dusfour,
  • Romain Girod and
  • Sébastien Briolant

Programs to control viruses transmitted by mosquitoes requires the implementation of surveillance tools. Over the past decade, Flinders Technology Associates (FTA®) cards, which preserve nucleic acids, have emerged as an innovating surveillance s...

  • Article
  • Open Access
2 Citations
2,397 Views
10 Pages

The Diagnostic Challenge of Cystic Echinococcosis in Humans: First Assessment of Underreporting Rates in Mongolia

  • Bolor Bold,
  • Christian Schindler,
  • Uranshagai Narankhuu,
  • Agiimaa Shagj,
  • Erdenebileg Bavuujav,
  • Sonin Sodov,
  • Tsogbadrakh Nyamdorj and
  • Jakob Zinsstag

Cystic echinococcosis (CE), caused by the larval stage of Echinococcus granulosus, is significantly underreported in Mongolia due to geographical remoteness, a lack of early diagnostics, and poor clinical management. This study aimed to provide a mor...

  • Article
  • Open Access
7 Citations
3,062 Views
10 Pages

Adolescents and young adults living with HIV (AYLHIV) in sub-Saharan Africa experience poorer HIV outcomes than adults, including lower ART adherence and virologic suppression. They also have high rates of unprotected sex, increasing the risk of adve...

  • Article
  • Open Access
2 Citations
4,046 Views
18 Pages

Rabies Realities: Navigating Barriers to Rabies Control in Rural Zambia—A Case Study of Manyinga and Mwansabombwe Districts

  • Muma Chipo Misapa,
  • Eugene C. Bwalya,
  • Ladslav Moonga,
  • Josiah Zimba,
  • Emmanuel S. Kabwali,
  • Mwenya Silombe,
  • Edgar Chilanzi Mulwanda,
  • Christopher Mulenga,
  • Martin C. Simuunza and
  • Hirofumi Sawa
  • + 2 authors

Rabies persists as a longstanding issue in Zambia, despite being preventable. The current control measures, including dog vaccination, population control, and movement restriction, guided by ‘The Control of Dogs Act Chapter 247 of the Laws of Z...

  • Article
  • Open Access
1,809 Views
13 Pages

Effectiveness of Three Sampling Approaches for Optimizing Mapping and Preventive Chemotherapy against Schistosoma mansoni in the Western Part of Côte d’Ivoire

  • Jean-Baptiste K. Sékré,
  • Mamadou Ouattara,
  • Nana R. Diakité,
  • Fidèle K. Bassa,
  • Rufin K. Assaré,
  • Jules N. Kouadio,
  • Gaoussou Coulibaly,
  • Agodio Loukouri,
  • Mathieu N. Orsot and
  • Jürg Utzinger
  • + 1 author

The elimination of schistosomiasis as a public health problem by 2030 is one of the main goals put forth in the World Health Organization’s roadmap for neglected tropical diseases. This study aimed to compare different sampling approaches to gu...

  • Article
  • Open Access
2 Citations
2,503 Views
11 Pages

The Comprehensive Management of Patients with Rhino-Orbito-Cerebral Mucormycosis; A Perspective from Antifungal Treatment to Prosthetic Rehabilitation: A Descriptive Cohort Study

  • Angélica Julián Castrejón,
  • Rosa Marene Hernández Martínez,
  • Diana Rivero Méndez,
  • Israel Nayensei Gil Velázquez,
  • Juan Heriberto Rodríguez Piña,
  • Juan Manuel Salgado Camacho,
  • Nicolás Teyes Calva,
  • Sayuri I. Espíndola Chavarría,
  • Patricia A. Meza-Meneses and
  • Carlos Alberto Castro-Fuentes

Surgical intervention is a key element in the management of patients diagnosed with mucormycosis. A retrospective cohort study was carried out, in which patients with a proven diagnosis of mucormycosis were evaluated over a period of 10 years, accord...

  • Article
  • Open Access
1 Citations
1,440 Views
8 Pages

Optimizing Trichiasis Case Finding to Attain the Elimination of Trachoma as a Public Health Problem

  • Joy Shu’aibu,
  • Grace Ajege,
  • Caleb Mpyet,
  • Michael Dejene,
  • Sunday Isiyaku,
  • Abubakar Tafida,
  • Michaela Kelly,
  • Innocent Emereuwa and
  • Paul Courtright

Background: As national trachoma programmes increase efforts to reduce the burden of trachomatous trichiasis (TT), TT case finding and referral are critical public health programme components. Our research aimed to explore the most effective and effi...

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Trop. Med. Infect. Dis. - ISSN 2414-6366