The Comprehensive Management of Patients with Rhino-Orbito-Cerebral Mucormycosis; A Perspective from Antifungal Treatment to Prosthetic Rehabilitation: A Descriptive Cohort Study
Abstract
:1. Introduction
2. Materials and Methods
3. Results
4. Discussion
5. Conclusions
Author Contributions
Funding
Institutional Review Board Statement
Informed Consent Statement
Data Availability Statement
Conflicts of Interest
References
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PATIENT | SEX | AGE (Years) | DM | CLINICAL PRESENTATION OF MUCORMYCOSIS | DIAGNOSIS (HISTO/CT/KOH) | ANTIFUNGAL | HOSPITAL STAY (Days) | OUTCOME | ||||
---|---|---|---|---|---|---|---|---|---|---|---|---|
NASAL | PARANASAL | ORBIT | CNS | OTHER ORGANS AFFECTED | ||||||||
1 | F | 41 | YES | 0 | 2c | 3c | 4d | NO | HISTO/CT | LAmB | 39 | DECEASED |
2 | M | 51 | YES | 0 | 2c | 3d | 4d | NO | HISTO/CT | LAmB | 31 | ALIVE |
3 | F | 22 | YES | 0 | 2c | 3c | 0 | NO | HISTO/CT | LAmB | 58 | ALIVE |
4 | M | 59 | YES | 1d | 2d | 3c | 0 | NO | HISTO/CT | LAmB | 89 | ALIVE |
5 | M | 69 | YES | 0 | 2c | 0 | 0 | NO | HISTO/CT | LAmB | 45 | ALIVE |
6 | M | 51 | YES | 0 | 2d | 3c | 0 | NO | HISTO/CT | LAmB | 8 | ALIVE |
7 | M | 45 | YES | 1d | 2d | 3d | 4d | NO | HISTO/CT | LAmB | 33 | DECEASED |
8 | F | 50 | YES | 1d | 2d | 3c | 0 | NO | HISTO/CT | LAmB | 6 | DECEASED |
9 | F | 64 | YES | 1d | 2d | 3c | 4d | NO | HISTO/CT | None | 0 | ALIVE |
10 * | M | 68 | YES | ND | ND | ND | ND | ND | HISTO | None | 0 | ALIVE |
11 | F | 25 | NO | 1c | 2c | 3c | 4d | NO | HISTO/CT | LAmB | 90 | ALIVE |
12 | M | 41 | YES | 0 | 2c | 3c | 4c | NO | HISTO/CT | LAmB | 79 | ALIVE |
13 | M | 6 | NO | 0 | 0 | 0 | 0 | YES | HISTO/CT | None | 3 | DECEASED |
14 | F | 45 | YES | 1d | 2d | 3c | 4d | NO | HISTO/CT | LAmB | 49 | ALIVE |
15 | F | 47 | YES | 1d | 2d | 3d | 4d | NO | HISTO/CT | LAmB | 43 | DECEASED |
16 | M | 35 | YES | 1 | 2d | 3c | 4d | NO | HISTO/CT | LAmB | 14 | DECEASED |
17 | F | 57 | YES | 1c | 2d | 0 | 0 | NO | HISTO/CT | None | 13 | DECEASED |
18 | M | 58 | NO | 0 | 0 | 0 | 0 | YES | HISTO/CT | LAmB | 5 | DECEASED |
19 | F | 34 | YES | 1 | 2c | 3c | 4c | NO | HISTO/CT | LAmB | 12 | ALIVE |
20 | M | 50 | YES | 1c | 2d | 3d | 4d | NO | CT/KOH | LAmB | 5 | ALIVE |
21 | F | 57 | ND | ND | ND | ND | ND | ND | ND | ND | ND | ALIVE |
22 | M | 53 | NO | 1d | 2c | 0 | 0 | NO | CUL/CT | LAmB | 36 | ALIVE |
PATIENT | SEX | AGE (Years) | SURGERY | SURGICAL TREATMENT | PROSTHESIS | TYPES OF PROSTHESES | ||||
---|---|---|---|---|---|---|---|---|---|---|
MAXILECTOMY | FLAP | TURBINECTOMY | EXENTERATION | SKULL BASE DRAINAGE | ||||||
1 | F | 41 | YES | YES | YES | YES | YES | NO | NO | |
2 | M | 51 | YES | YES | YES | YES | YES | NO | YES | PALATAL OBTURATOR (SURGICAL AND TRANSCISIONAL) |
3 | F | 22 | YES | YES | YES | YES | YES | YES | YES | PALATAL OBTURATOR (SURGICAL, TRANSCISIONAL, AND DEFINITIVE), ORBITOFACIAL PROSTHESIS (EYE AND EYELID) |
4 | M | 59 | YES | NO | NO | NO | YES | NO | YES | EYE IMPLANT |
6 | M | 51 | YES | YES | NO | YES | YES | NO | NO | DOES NOT APPLY |
11 | F | 25 | YES | YES | NO | NO | YES | YES | YES | |
12 | M | 41 | YES | NO | YES | NO | YES | YES | YES | CRANIAL AND ORBITOFACIAL PROSTHESIS (EYE AND EYELID) |
13 | M | 6 | YES | NO | NO | NO | NO | NO | NO | |
14 | F | 45 | YES | YES | NO | YES | YES | YES | YES | PALATAL OBTURATOR (SURGICAL AND TRANSCISIONAL) |
15 | F | 47 | YES | NO | YES | NO | NO | NO | NO | |
18 | M | 58 | YES | YES | YES | YES | NO | NO | NO | |
21 * | F | 57 | YES | YES | NO | NO | YES | NO | YES | TRANSCISIONAL PALATAL OBTURATOR AND ORBITOFACIAL PROSTHESIS (EYE AND EYELID) |
22 | M | 53 | YES | YES | YES | NO | NO | NO | YES | PALATAL OBTURATOR (SURGICAL AND TRANSCISIONAL) |
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Julián Castrejón, A.; Hernández Martínez, R.M.; Rivero Méndez, D.; Gil Velázquez, I.N.; Rodríguez Piña, J.H.; Salgado Camacho, J.M.; Teyes Calva, N.; Espíndola Chavarría, S.I.; Meza-Meneses, P.A.; Castro-Fuentes, C.A. The Comprehensive Management of Patients with Rhino-Orbito-Cerebral Mucormycosis; A Perspective from Antifungal Treatment to Prosthetic Rehabilitation: A Descriptive Cohort Study. Trop. Med. Infect. Dis. 2024, 9, 158. https://doi.org/10.3390/tropicalmed9070158
Julián Castrejón A, Hernández Martínez RM, Rivero Méndez D, Gil Velázquez IN, Rodríguez Piña JH, Salgado Camacho JM, Teyes Calva N, Espíndola Chavarría SI, Meza-Meneses PA, Castro-Fuentes CA. The Comprehensive Management of Patients with Rhino-Orbito-Cerebral Mucormycosis; A Perspective from Antifungal Treatment to Prosthetic Rehabilitation: A Descriptive Cohort Study. Tropical Medicine and Infectious Disease. 2024; 9(7):158. https://doi.org/10.3390/tropicalmed9070158
Chicago/Turabian StyleJulián Castrejón, Angélica, Rosa Marene Hernández Martínez, Diana Rivero Méndez, Israel Nayensei Gil Velázquez, Juan Heriberto Rodríguez Piña, Juan Manuel Salgado Camacho, Nicolás Teyes Calva, Sayuri I. Espíndola Chavarría, Patricia A. Meza-Meneses, and Carlos Alberto Castro-Fuentes. 2024. "The Comprehensive Management of Patients with Rhino-Orbito-Cerebral Mucormycosis; A Perspective from Antifungal Treatment to Prosthetic Rehabilitation: A Descriptive Cohort Study" Tropical Medicine and Infectious Disease 9, no. 7: 158. https://doi.org/10.3390/tropicalmed9070158
APA StyleJulián Castrejón, A., Hernández Martínez, R. M., Rivero Méndez, D., Gil Velázquez, I. N., Rodríguez Piña, J. H., Salgado Camacho, J. M., Teyes Calva, N., Espíndola Chavarría, S. I., Meza-Meneses, P. A., & Castro-Fuentes, C. A. (2024). The Comprehensive Management of Patients with Rhino-Orbito-Cerebral Mucormycosis; A Perspective from Antifungal Treatment to Prosthetic Rehabilitation: A Descriptive Cohort Study. Tropical Medicine and Infectious Disease, 9(7), 158. https://doi.org/10.3390/tropicalmed9070158