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Tropical Medicine and Infectious Disease, Volume 6, Issue 4

December 2021 - 43 articles

Cover Story: Mediterranean spotted fever (MSF) is a zoonotic vector-borne infection that is caused by the Rickettsia conorii subspecies conorii. Although MSF may present with typical manifestations, such as fever, maculopapular rash, and a characteristic eschar (“tache noire”), it can also have atypical features that make the diagnosis of the disease rather challenging. Due to the angiotropism of R. conorii, severe multi-organ complications can also arise. A thorough understanding of the currently available laboratory diagnostic assays is required for the diagnosis of MSF. Our knowledge concerning the epidemiology as well as the pathogenesis of the disease has advanced significantly over the years, yet areas of uncertainty still exist. View this paper
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Articles (43)

  • Article
  • Open Access
14 Citations
4,625 Views
14 Pages

An Intra-COVID-19 Assessment of Hand Hygiene Facility, Policy and Staff Compliance in Two Hospitals in Sierra Leone: Is There a Difference between Regional and Capital City Hospitals?

  • Sulaiman Lakoh,
  • Emmanuel Firima,
  • Christine Ellen Elleanor Williams,
  • Sarah K. Conteh,
  • Mohamed Boie Jalloh,
  • Mohamed Gbeshay Sheku,
  • Olukemi Adekanmbi,
  • Stephen Sevalie,
  • Sylvia Adama Kamara and
  • Mohamed Akmed Salim Kamara
  • + 15 authors

Although hand hygiene (HH) is the most effective intervention to reduce the spread of infections, there are limited data on HH facilities, policy, and compliance in sub-Saharan Africa. This cross-sectional study is aimed at assessing HH using the WHO...

  • Review
  • Open Access
6 Citations
4,260 Views
9 Pages

Screening for Chagas Disease during Pregnancy in the United States—A Literature Review

  • Elizabeth G. Livingston,
  • Ryan Duggal and
  • Sarah Dotters-Katz

Obstetrician-gynecologists in the United States have little clinical experience with the epidemiology, pathophysiology, diagnosis, and treatment of Chagas disease. The number of US parturients born in Central and South America has continued to increa...

  • Article
  • Open Access
13 Citations
5,175 Views
21 Pages

In the first year and a half of the COVID-19 pandemic, South Korea suffered significantly less social and economic damage than the V4 countries (Czech Republic, Hungary, Poland, and Slovakia) despite less stringent restrictive measures. In order to e...

  • Article
  • Open Access
2 Citations
3,637 Views
11 Pages

Can Patient Navigators Help Potential TB Patients Navigate the Diagnostic and Treatment Pathways? An Implementation Research from India

  • Tushar Garg,
  • Vikas Panibatla,
  • Joseph P. Carel,
  • Achanta Shanta,
  • Manish Bhardwaj and
  • Miranda Brouwer

Navigating the Indian health system is a challenge for people with tuberculosis (TB) symptoms. The onus of organizing care is on the patient and their families alone. Factors like gender discrimination and opportunity costs further aggravate this. As...

  • Communication
  • Open Access
7 Citations
5,461 Views
9 Pages

Prevalence and Molecular Characterization of Rickettsia spp. from Wild Small Mammals in Public Parks and Urban Areas of Bangkok Metropolitan, Thailand

  • Artharee Rungrojn,
  • Kittipong Chaisiri,
  • Yossapong Paladsing,
  • Serge Morand,
  • Jiraphan Junjhon,
  • Stuart D. Blacksell and
  • Peeraya Ekchariyawat

Rural areas usually show a higher prevalence of rickettsial infection than urban areas. However, information on the rickettsial infection status in urban settings (e.g., built-up areas and city parks) is still limited, particularly in the Bangkok met...

  • Communication
  • Open Access
5 Citations
4,323 Views
6 Pages

Seasonality of Acute Lyme Disease in Children

  • Kathryn M. Sundheim,
  • Michael N. Levas,
  • Fran Balamuth,
  • Amy D. Thompson,
  • Desiree N. Neville,
  • Aris C. Garro,
  • Anupam B. Kharbanda,
  • Michael C. Monuteaux and
  • Lise E. Nigrovic

Due to the life cycle of its vector, Lyme disease has known seasonal variation. However, investigations focused on children have been limited. Our objective was to evaluate the seasonality of pediatric Lyme disease in three endemic regions in the Uni...

  • Communication
  • Open Access
3 Citations
4,139 Views
9 Pages

Impetigo affects millions of children worldwide. Most guidelines recommend antibiotics as first-line treatment; however, topical antiseptics present a potentially valuable, understudied, antibiotic-sparing treatment for mild impetigo. We aimed to det...

  • Review
  • Open Access
14 Citations
4,873 Views
10 Pages

Many questions remain unanswered regarding the epidemiology, pathophysiology, diagnosis, treatment, and monitoring of Trypanosoma cruzi infection in people with HIV (PWH). The reported prevalence of T. cruzi infection in PWH living in endemic countri...

  • Article
  • Open Access
1 Citations
4,024 Views
11 Pages

Spatial and Temporal Distribution of Rodents during the Epizootic and Enzootic Periods of Plague, with a Focus on Exu, Northeastern Brazil

  • Diego Leandro Reis da Silva Fernandes,
  • Matheus Filgueira Bezerra,
  • Bruna Mendes Duarte,
  • Mayara Paes de França Silva,
  • Hadassa de Almeida Souza,
  • Elainne Christine de Souza Gomes and
  • Alzira Maria Paiva de Almeida

The plague caused by the Yersinia pestis bacterium is primarily a flea-transmitted zoonosis of rodents that can also be conveyed to humans and other mammals. In this work, we analyzed the spatial and temporal distribution of rodent populations during...

  • Article
  • Open Access
7 Citations
4,418 Views
9 Pages

Methicillin-Resistant Coagulase Negative Staphylococci and Their Antibiotic Susceptibility Pattern from Healthy Dogs and Their Owners from Kathmandu Valley

  • Muna Khanal,
  • Prabhu Raj Joshi,
  • Saroj Paudel,
  • Mahesh Acharya,
  • Komal Raj Rijal,
  • Prakash Ghimire and
  • Megha Raj Banjara

This cross-sectional study was designed to identify information on the frequency, antimicrobial resistance and species diversity of methicillin-resistant coagulase negative staphylococci (MRCoNS) among pet dogs and humans within households. Fifty fiv...

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Trop. Med. Infect. Dis. - ISSN 2414-6366