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Tropical Medicine and Infectious Disease, Volume 6, Issue 4

December 2021 - 43 articles

Cover Story: Mediterranean spotted fever (MSF) is a zoonotic vector-borne infection that is caused by the Rickettsia conorii subspecies conorii. Although MSF may present with typical manifestations, such as fever, maculopapular rash, and a characteristic eschar (“tache noire”), it can also have atypical features that make the diagnosis of the disease rather challenging. Due to the angiotropism of R. conorii, severe multi-organ complications can also arise. A thorough understanding of the currently available laboratory diagnostic assays is required for the diagnosis of MSF. Our knowledge concerning the epidemiology as well as the pathogenesis of the disease has advanced significantly over the years, yet areas of uncertainty still exist. View this paper
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Articles (43)

  • Article
  • Open Access
6 Citations
4,338 Views
13 Pages

Trends of HIV-Related Cancer Mortality between 2001 and 2018: An Observational Analysis

  • Chinmay Jani,
  • Omar Al Omari,
  • Harpreet Singh,
  • Alexander Walker,
  • Kripa Patel,
  • Christian Mouchati,
  • Amr Radwan,
  • Zuha Pandit,
  • Georgina Hanbury and
  • Conor Crowley
  • + 5 authors

The burden of AIDS-defining cancers has remained relatively steady for the past two decades, whilst the burden of non-AIDS-defining cancer has increased. Here, we conduct a study to describe mortality trends attributed to HIV-associated cancers in 31...

  • Case Report
  • Open Access
8 Citations
3,395 Views
8 Pages

Myocarditis in a Pediatric Patient with Campylobacter Enteritis: A Case Report and Literature Review

  • Anastasios-Panagiotis Chantzaras,
  • Spyridon Karageorgos,
  • Panagiota Panagiotou,
  • Elissavet Georgiadou,
  • Theodora Chousou,
  • Kalliopi Spyridopoulou,
  • Georgios Paradeisis,
  • Christina Kanaka-Gantenbein and
  • Evanthia Botsa

Myocarditis represents a potential complication of various infectious and noninfectious agents and a common diagnostic challenge for clinicians. Data regarding Campylobacter-associated myocarditis are limited. Here, a case of a 13-year-old female wit...

  • Review
  • Open Access
13 Citations
5,105 Views
19 Pages

Nodding Syndrome: A Scoping Review

  • Gasim Omer Elkhalifa Abd-Elfarag,
  • Arthur Wouter Dante Edridge,
  • René Spijker,
  • Mohamed Boy Sebit and
  • Michaël B. van Hensbroek

Nodding syndrome (NS) is a debilitating yet often neglected neurological disease affecting thousands of children in several sub-Saharan African countries. The cause of NS remains unknown, and effective treatment options are lacking. Moreover, knowled...

  • Article
  • Open Access
6 Citations
4,246 Views
13 Pages

Occurrence of Cryptosporidium Infection and Associated Risk Factors among HIV-Infected Patients Attending ART Clinics in the Central Region of Ghana

  • Kwabena Dankwa,
  • Samuel Victor Nuvor,
  • Dorcas Obiri-Yeboah,
  • Patrick Kwame Feglo and
  • Mohamed Mutocheluh

Cryptosporidium species are intestinal protozoan parasites that infect and cause diarrhoea in animals and humans. The current study was conducted to determine the prevalence and risk factors of Cryptosporidium infection among HIV-infected patients in...

  • Case Report
  • Open Access
5 Citations
4,375 Views
10 Pages

Acalculous Cholecystitis in a Young Adult with Scrub Typhus: A Case Report and Epidemiology of Scrub Typhus in the Maldives

  • Hisham Ahmed Imad,
  • Aishath Azna Ali,
  • Mariyam Nahuza,
  • Rajan Gurung,
  • Abdulla Ubaid,
  • Aishath Maeesha,
  • Sariu Ali Didi,
  • Rajib Kumar Dey,
  • Abdullah Isneen Hilmy and
  • Aishath Hareera
  • + 5 authors

Scrub typhus is a neglected tropical disease predominantly occurring in Asia. The causative agent is a bacterium transmitted by the larval stage of mites found in rural vegetation in endemic regions. Cases of scrub typhus frequently present as acute...

  • Article
  • Open Access
2 Citations
4,309 Views
16 Pages

Knowledge, Attitudes and Practices Regarding Sylvatic Rabies among High-Risk Households in Ceará State, Brazil

  • Naylê Francelino Holanda Duarte,
  • Patrícia Pereira Lima Barbosa,
  • Danielle Bastos Araujo,
  • Silvana Regina Favoretto,
  • Phyllis Catharina Romijn,
  • Raphael William Pontes Neres,
  • Raquel Holanda Varela,
  • Walber Feijó de Oliveira,
  • Carlos Henrique Alencar and
  • Jorg Heukelbach

Rabies transmitted by sylvatic populations has become an increasing concern in Brazil. A total of 113 participants with a history of contact with sylvatic populations were interviewed in 27 municipalities of Ceará State in northeast Brazil. Qu...

  • Case Report
  • Open Access
8 Citations
4,935 Views
12 Pages

Pandora’s Box: Disseminated Coccidioidomycosis Associated with Self-Medication with an Unregulated Potent Corticosteroid Acquired in Mexico

  • Alejandro Jose Coba,
  • Patricia K. Sallee,
  • Danielle O. Dixon,
  • Rahaf Alkhateb and
  • Gregory M. Anstead

Coccidioidomycosis (CM), caused by the dimorphic fungi Coccidioides immitis and C. posadasii, typically presents as acute or chronic pulmonary disease. However, disseminated disease occurs in about 1% of patients. Disseminated CM may affect multiple...

  • Article
  • Open Access
12 Citations
3,862 Views
9 Pages

Tracking Animal Reservoirs of Pathogenic Leptospira: The Right Test for the Right Claim

  • Yann Gomard,
  • Koussay Dellagi,
  • Steven M. Goodman,
  • Patrick Mavingui and
  • Pablo Tortosa

Leptospirosis is the most prevalent bacterial zoonosis worldwide and, in this context, has been extensively investigated through the One Health framework. Diagnosis of human leptospirosis includes molecular and serological tools, with the serological...

  • Systematic Review
  • Open Access
22 Citations
9,487 Views
22 Pages

Active Case Finding for Tuberculosis in India: A Syntheses of Activities and Outcomes Reported by the National Tuberculosis Elimination Programme

  • Sharath Burugina Nagaraja,
  • Pruthu Thekkur,
  • Srinath Satyanarayana,
  • Prathap Tharyan,
  • Karuna D. Sagili,
  • Jamhoih Tonsing,
  • Raghuram Rao and
  • Kuldeep Singh Sachdeva

India launched a national community-based active TB case finding (ACF) campaign in 2017 as part of the strategic plan of the National Tuberculosis Elimination Programme (NTEP). This review evaluated the outcomes for the components of the ACF campaign...

  • Communication
  • Open Access
14 Citations
5,656 Views
6 Pages

A Practical Approach to Screening for Strongyloides stercoralis

  • Luisa Carnino,
  • Jean-Marc Schwob,
  • Laurent Gétaz,
  • Beatrice Nickel,
  • Andreas Neumayr and
  • Gilles Eperon

Strongyloides stercoralis, causative agent of a neglected tropical disease, is a soil-transmitted helminth which may cause lifelong persisting infection due to continuous autoinfection. In the case of immunosuppression, life-threatening hyperinfectio...

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Trop. Med. Infect. Dis. - ISSN 2414-6366Creative Common CC BY license