2025 March - 70 articles
Diffuse large B-cell lymphoma (DLBCL), accounting for 31% of non-Hodgkin lymphomas, remains recalcitrant to conventional therapies due to chemoresistance, metastatic progression, and immunosuppressive microenvironments. We report a novel injectable F...
Efficient and precise cancer therapy remains a challenge due to limitations in current treatment modalities. In this study, we developed a multifunctional hydrogel system that integrates photothermal therapy (PTT) and chemotherapy to achieve combined...
The hydrogel patent landscape is characterized by rapid growth and diverse applications, particularly in the biomedical field. Advances in material science, chemistry, novel manufacturing techniques, and a deeper understanding of biological systems h...
Honey has been recognised for centuries for its potential therapeutic properties, and its application in wound healing has gained attention due to its antimicrobial, anti-inflammatory, and regenerative properties. With the rapid increase in multidrug...
Vulvovaginal symptoms affect up to 39% of women. These symptoms have a significant impact on quality of life and are often linked to imbalances in the vaginal microbiota. This study evaluates the therapeutic efficacy of a zinc-containing hydroxyethyl...
Mesenchymal stem cells (MSCs) can differentiate into chondrocytes provided with the appropriate environmental cues. In this study, we loaded human adipose-derived stem cells (hAdMSCs) into collagen/alginate hydrogels, which have been shown to induce...
Hydrogels are promising materials for biomedical applications due to their tunable properties. Despite significant research on optimizing the mechanical and rheological properties of chitosan hydrogels, a comprehensive analysis incorporating pH and m...
Industrial textile wastewater containing both heavy metals and dyes has been massively produced. In this study, semi-interpenetrating polymer network structures of sodium alginate (SA)/polyvinyl alcohol (PVA)/κ-carrageenan (CG) aerogel beads we...
To investigate the feasibility of cellulose extraction from lignocellulosic waste biomass using ionic liquids—a sustainable and efficient approach—for preparing cellulose aerogel adsorbents, we employed a fully green amino acid-derived io...
The high biocompatibility and the key role of collagen in bone extracellular matrix make it useful for tissue engineering. However, the high demand, costs, and challenges of extracting good-quality collagen have led to the use of collagen derivatives...
Buccal drug delivery systems often struggle with poor drug solubility, limited adhesion, and rapid clearance, leading to suboptimal therapeutic outcomes. To address these limitations, we developed a novel hybrid eutectogel composed of xanthan gum (XT...
Hydrogels are innovative materials characterized by a water-swollen, crosslinked polymeric network capable of retaining substantial amounts of water while maintaining structural integrity. Their unique ability to swell or contract in response to envi...
Hydrogel microneedles (HMNs) have emerged as a transformative platform for minimally invasive drug delivery and biosensing, offering enhanced bioavailability, controlled drug release, and real-time biomarker detection. By leveraging swelling hydrogel...
A sol-gel approach was used to prepare a thin hydrogel membrane based on an organic-inorganic polymer matrix embedded with pre-synthesized gold nanoparticles (AuNPs). The organic polymers utilized were poly(vinyl alcohol) (PVA) and poly(ethylene oxid...
Gel electrolyte-gated organic electrochemical transistors (OECTs) are promising bioelectronic devices known for their high transconductance, low operating voltage, and integration with biological systems. Despite extensive research on the performance...
The application of crayfish muscle in surimi products is a potential way to promote their processing and ensure that it is of a high value. In this study, a one-way completely randomized design was used to prepare mixed surimi gels with different pro...
Polyzwitterion (PZW) hydrogel has excellent marine anti-biofouling performance, but it is difficult to effectively work for a long time in natural seawater due to its weak mechanical strength. In this study, a new natural rubber (NR)-PZW composite hy...
This study investigates the synthesis and properties of innovative poly(oligo(alkylene glycol)) methacrylate hydrogels synthesized via gamma radiation-induced copolymerization and the crosslinking of oligo(ethylene glycol) methacrylate (OEGMA) and ol...
Resorbable microparticles can be added to hydrogel-based biocompatible scaffolds to improve their mechanical characteristics and allow localised drug delivery, which will aid in tissue repair and regeneration. It is well-known that bioprinting is imp...
Cartilage damage is common in sports injuries and cartilage-related diseases, such as degenerative joint and rheumatic disorders. Autologous chondrocyte implantation (ACI) is a widely used cell-based therapy for repairing cartilage damage in clinical...
Polysaccharide-based hydrogels have emerged as indispensable materials in tissue engineering and wound healing, offering a unique combination of biocompatibility, biodegradability, and structural versatility. Indeed, their three-dimensional polymeric...
Hydrogels find widespread use in bioapplications for their ability to retain large amounts of water while maintaining structural integrity. In this article, we investigate hybrid hydrogels made of nanocellulose and either amino–polyethylenglyco...
This study explores the impact of pore volume distribution on the structural, thermal, and mechanical properties of spinodal phase-separated silica gels synthesized with poly(ethylene oxide) as a phase-separating agent. By systematically varying gela...
This study investigated the structural, rheological, and microstructural properties of soy protein isolate (SPI) induced by tyrosinase-catalyzed crosslinking with tannic acid (TA) at 25 °C under neutral conditions at pH 6.5. The particle size and...
Honey has long been recognized for its medicinal properties, particularly in wound healing. Recent advancements in material science have led to the development of honey-containing hydrogels, combining the natural healing properties of honey with the...
This study investigated the feasibility of using semi-dry desulfurization ash (DA) in combination with blast furnace slag (BFS) to prepare gelling materials, aiming to improve the resource utilization of DA. The effects of DA dosage and mechanical gr...
Hydrogels are network polymers with high water-bearing capacity resembling the extracellular matrix. Recently, many studies have focused on synthesizing hydrogels from natural sources as they are biocompatible, biodegradable, and readily available. H...
Three-dimensional bioprinting is a new advance in tissue engineering and regenerative medicine. Bioprinting allows manufacturing three-dimensional (3D) structures that mimic tissues or organs. The bioinks used are mainly made of natural or synthetic...
In recent years, hydrogels have emerged as promising candidates for bone defect repair due to their excellent biocompatibility, high porosity, and water-retentive properties. However, conventional hydrogels face significant challenges in clinical tra...
Oropharyngeal dysphagia and pain are prevalent concerns in the geriatric population. Therefore, this study investigates advances in the development of cannabidiol (CBD) gummies using 3D printing technology and compares them to commercially available...
Postoperative adhesions are common complications following surgery, often accompanied by pain and inflammation that significantly diminish patients’ quality of life. Moreover, managing postoperative adhesions incurs substantial cost, imposing a...
Over the past years, numerous novel dosage forms, including gels, have been investigated for paediatric treatment due to the need to provide flexible dose adjustment possibilities, as well as a patient-friendly approach to drug delivery. Simultaneous...
Yanbian cattle, a high-quality indigenous breed in China, were selected due to their unique biological characteristics, underutilized bone byproducts, and potential as a halal-compliant gelatin source, addressing the growing demand for alternatives t...
Alginate hydrogels are integral to many cell-based models in tissue engineering and regenerative medicine. As a natural biomaterial, the properties of alginates can vary and be widely adjusted through the gelation process, making them versatile addit...
The mechanical stability of carbon aerogels, particularly their thermal insulation performance, is closely linked to their elastic modulus. This property plays a crucial role in determining the material’s overall mechanical stability. The objec...
This study discusses the preparation of biopolymeric hydrogels (a biomaterial) via different techniques, such as casting and extrusion, to compare the effects of the process and the use of citric acid as a crosslinker on the morphology, physicochemic...
This study investigated the effects of calcium oxide (CaO) derived from eggshells on the gelation properties of surimi prepared from giant snakehead (Channa micropeltes). Surimi gels were enriched with CaO at concentrations of 0, 2, 4, 6, 8, and 10 &...
Foam and hydrogel profile control are commonly utilized water-blocking and profile modification techniques in oil fields. This study integrates a foam system with a gel system, employing an organic titanium crosslinking agent to crosslink polyvinyl a...
The comonomer bisphenol A (BPA) finds applications in the plastics industry, where it is used in the production of polycarbonates, plastics, PVC, thermal paper, epoxy and vinyl ester resins, and polyurethane. The water, with which many of these mater...
Hydrogels and microgels are emerging as pivotal platforms in biomedicine, with significant potential in targeted drug delivery, enhanced infection management, and tissue repair and regeneration. These gels, characterized by their high water content,...
Biopolymer hydrogel-based scaffold materials have received a lot of interest in tissue engineering and regenerative medicine because of their unique characteristics, which include biocompatibility, biodegradability, and the ability to replicate the n...
Cyclodextrin (CD)–hydrogel hybrids have emerged as versatile and multifunctional drug delivery systems, offering enhanced solubility, controlled drug release, and improved bioavailability. By combining the inclusion complexation properties of C...
The substitution of animal proteins with plant-based ones to fit environmental and economic demands is a challenge in gel applications. This study examined the thermal elation of mixtures of pea protein isolate (PPI) and egg white proteins (EWPs) at...
In this study, a hydrogel material based on porcine gelatin and sodium alginate was synthesized for use as a dressing for chronic wound treatment. The hydrogels were covalently cross-linked using polyethylene glycol diglycidyl ether (PEGDE 500), and...
Bone defects resulting from trauma, tumors, or congenital conditions pose significant challenges for natural healing and often require grafting solutions. While autografts remain the gold standard, their limitations, such as restricted availability a...
Bone tissue engineering has emerged as a promising approach to addressing the limitations of traditional bone grafts for repairing bone defects. This regenerative medicine strategy leverages biomaterials, growth factors, and cells to create a favorab...
Medical and aromatic plant extracts are often very sensitive to environmental, gastrointestinal, and processing conditions despite their health benefits. Therefore, they can be rapidly inactivated. Microencapsulation is used to overcome such challeng...
To reduce the hard texture of cooked early indica rice, two types of polydextrose (ST with 1% moisture content (MC) and XG with 4.7% MC) were added at 0%, 3%, 5%, 7%, and 10%, respectively, to the cooking milled rice polished from the paddies of the...
Cancer is a global health concern. Various therapeutic approaches, including chemotherapy, photodynamic therapy, and immunotherapy, have been developed for cancer treatment. Silica nanoparticles, quantum dots, and metal–organic framework (MOF)-...
In the 21st century, sustainable agriculture is expected to become a major contributor to food security and improved nutrition. Amine–epoxide-based materials have great potential for use in agriculture due to their tunable physicochemical featu...
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