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Medicines, Volume 8, Issue 11

2021 November - 12 articles

Cover Story: In this study of the UNOS/OPTN database from 2015 through 2019, we aimed to assess the risk factors and feature importance of acute rejection among Black kidney transplant recipients utilizing RF vs. traditional multivariable logistic regression analysis. The application of tree-based RF feature importance and the feature interaction network analysis framework identified the recipient age, ESKD etiology, PRA, cold ischemia time, donor age, HLA DR mismatch, BMI, serum albumin, degree of HLA mismatch, education level, and dialysis duration as important variables in the RF models for acute rejection among Black kidney transplant recipients in the United States. View this paper
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Articles (12)

  • Article
  • Open Access
10 Citations
6,444 Views
15 Pages

Neuron-Specific Enolase (NSE) Predicts Long-Term Mortality in Adult Patients after Cardiac Arrest: Results from a Prospective Trial

  • Jonas Müller,
  • Benjamin Bissmann,
  • Christoph Becker,
  • Katharina Beck,
  • Nina Loretz,
  • Sebastian Gross,
  • Simon A. Amacher,
  • Chantal Bohren,
  • Hans Pargger and
  • Sabina Hunziker
  • + 3 authors

17 November 2021

Background: We investigated whether Neuron-specific enolase (NSE) serum concentration predicts long-term mortality and poor neurological outcome in adult cardiac arrest patients. Methods: Within this prospective observational study, we included conse...

  • Article
  • Open Access
10 Citations
3,882 Views
10 Pages

The Impact of the COVID-19 Pandemic on Medical Imaging Case Volumes in Aseer Region: A Retrospective Study

  • Magbool Alelyani,
  • Ali Alghamdi,
  • Nasser Shubayr,
  • Yazeed Alashban,
  • Hajar Almater,
  • Sultan Alamri and
  • Ahmad Joman Alghamdi

12 November 2021

COVID-19 has had a significant impact on global health systems. The aim of this study was to evaluate how imaging volumes and imaging types in radiology departments have been affected by the COVID-19 pandemic across different locations. Methods: Imag...

  • Article
  • Open Access
5 Citations
3,657 Views
13 Pages

12 November 2021

Background and Objectives: To examine the effect of maternal breastfeeding on the subsequent risk of diabetes in parous Korean women aged >50 years. Materials and Methods: A total of 14,433 participants from the Korea National Health and Nutrition...

  • Review
  • Open Access
2 Citations
5,741 Views
8 Pages

10 November 2021

Cancer is a global health and economic issue. The majority of anticancer therapies become ineffective due to frequent genomic turnover and chemoresistance. Furthermore, chemotherapy and radiation are non-specific, killing all rapidly dividing cells i...

  • Case Report
  • Open Access
3 Citations
5,411 Views
9 Pages

A Rare Case of Recurrent Generalized Peritonitis Caused by Spontaneous Urinary Bladder Rupture after Radiotherapy: A Case Report and Literature Review

  • Yusuke Watanabe,
  • Shun Yamazaki,
  • Hanako Yokoyama,
  • Shunta Yakubo,
  • Akihiko Osaki,
  • Kenichi Takaku,
  • Munehiro Sato,
  • Nobuo Waguri and
  • Shuji Terai

5 November 2021

Since generalized peritonitis is a fatal disease, accurate diagnosis and treatment are important. In this paper, we report a case of recurrent generalized peritonitis associated with spontaneous urinary bladder rupture (SBR). A 65 year old woman, who...

  • Case Report
  • Open Access
3 Citations
17,807 Views
9 Pages

5 November 2021

Current FDA-approved antifibrotic treatments for Idiopathic Pulmonary Fibrosis slow down disease progression but have little impact on symptoms or quality of life in patients. This study was conducted to evaluate the effects of systemic enzymes in re...

  • Article
  • Open Access
10 Citations
4,326 Views
19 Pages

Feature Importance of Acute Rejection among Black Kidney Transplant Recipients by Utilizing Random Forest Analysis: An Analysis of the UNOS Database

  • Charat Thongprayoon,
  • Caroline C. Jadlowiec,
  • Napat Leeaphorn,
  • Jackrapong Bruminhent,
  • Prakrati C. Acharya,
  • Chirag Acharya,
  • Pattharawin Pattharanitima,
  • Wisit Kaewput,
  • Boonphiphop Boonpheng and
  • Wisit Cheungpasitporn

2 November 2021

Background: Black kidney transplant recipients have worse allograft outcomes compared to White recipients. The feature importance and feature interaction network analysis framework of machine learning random forest (RF) analysis may provide an unders...

  • Article
  • Open Access
6 Citations
5,039 Views
13 Pages

Recent Trends of Metabolic Syndrome and Its Components in Military Recruits from Saudi Arabia

  • Hamoud Abdullah Al-Shehri,
  • Abdulrahman Khazim Al-Asmari,
  • Haseeb Ahmad Khan,
  • Ghaleb Bin Horaib,
  • Ahmed Al-Buraidi,
  • Abdullah Ali Al-Sharif,
  • Saeed Ghander Kadasah,
  • Saud Al-Omani,
  • Fayez S. Mohammed and
  • Nasreddien Mohammed Osman
  • + 1 author

30 October 2021

Metabolic syndrome (Met-S) constitutes the risk factors and abnormalities that markedly increase the probability of developing diabetes and coronary heart disease. An early detection of Met-S, its components and risk factors can be of great help in p...

  • Brief Report
  • Open Access
3,378 Views
7 Pages

29 October 2021

Introduction: It is currently considered that screening for frailty in elderly subjects is a major public health issue. Methods: a cross-sectional pilot study involving elderly subjects (over 75 years of age) admitted at the emergency department of t...

  • Article
  • Open Access
4 Citations
3,587 Views
12 Pages

29 October 2021

Background: Transfusion-transmissible infections are well-known global health challenges. The present study is proposed to investigate the seropositivity of anti-HIV1/2, anti-HCV, HBsAg, and anti-T.pallidum among volunteer blood donors of Kosti Obste...

  • Article
  • Open Access
5 Citations
3,502 Views
8 Pages

Factors Affecting Dietary Improvements in Elderly Residents of Long-Term Care Institutions Receiving Domiciliary Dental Care

  • Hitomi Kikuchi,
  • Akira Komatsuzaki,
  • Sachie Ono,
  • Miwa Sirono,
  • Shiho Motoi,
  • Asami Iguchi and
  • Mio Susuga

21 October 2021

Background: Oral disabilities occur due to tooth loss. This study aimed to investigate oral and systemic factors related to diet in elderly residents receiving domiciliary dental care. Methods: The subjects were 74 consenting residents. Survey items...

  • Article
  • Open Access
3,970 Views
8 Pages

Clinical Outcome of Patients Submitted to Liver Resection in the Context of Metastatic Breast Cancer: A Study of a Tertiary Hospital Center

  • Jorge Nogueiro,
  • Vitor Devezas,
  • Fabiana Sousa,
  • Cristina Fernandes,
  • Fernando Osório,
  • Susy Costa,
  • André Magalhães,
  • Henrique Mora,
  • Diana Gonçalves and
  • Elisabete Barbosa
  • + 4 authors

20 October 2021

Introduction: Breast cancer is the most incident cancer in the world, accounting for 25% of new cancers per year in females. It is the most frequent malignancy in women, being the fifth cause of death from cancer worldwide. Approximately 5 to 10% of...

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Medicines - ISSN 2305-6320