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Biomolecules 2019, 9(3), 94; https://doi.org/10.3390/biom9030094

Advance on Resveratrol Application in Bone Regeneration: Progress and Perspectives for Use in Oral and Maxillofacial Surgery

1
Department of Biological, Chemical and Pharmaceutical Sciences and Technologies, University of Palermo, 90123 Palermo, Italy
2
Department of Surgical, Oncological and Oral Sciences, University of Palermo, 90127 Palermo, Italy
*
Author to whom correspondence should be addressed.
Received: 9 January 2019 / Revised: 2 March 2019 / Accepted: 4 March 2019 / Published: 8 March 2019
(This article belongs to the Special Issue Key Biomolecules in Bone Resorption)
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PDF [296 KB, uploaded 14 March 2019]

Abstract

The natural polyphenol Resveratrol (RSV) claims numerous positive effects on health due to the well documented biological effects demonstrating its potential as a disease-preventing agent and as adjuvant for treatment of a wide variety of chronic diseases. Since several studies, both in vitro and in vivo, have highlighted the protective bone aptitude of RSV both as promoter of osteoblasts’ proliferation and antagonist of osteoclasts’ differentiation, they could be interesting in view of applications in the field of dentistry and maxillofacial surgery. This review has brought together experimental findings on the use of RSV in the regeneration of bone tissue comprising also its application associated with scaffolds and non-transfusional hemocomponents. View Full-Text
Keywords: Resveratrol; bone-regeneration; craniofacial tissue; alveolar bone loss; bone defect; resveratrol scaffold Resveratrol; bone-regeneration; craniofacial tissue; alveolar bone loss; bone defect; resveratrol scaffold
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited (CC BY 4.0).
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Murgia, D.; Mauceri, R.; Campisi, G.; De Caro, V. Advance on Resveratrol Application in Bone Regeneration: Progress and Perspectives for Use in Oral and Maxillofacial Surgery. Biomolecules 2019, 9, 94.

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