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Short Communication

HPLC Analysis and Cytotoxicity of n-Butanol Extract from Glyphaea brevis Roots Against C6 Glioma Cells

1
Laboratoire de Chimie Bioorganique et de Substances Naturelles (LCBOSN), UFR-SFA, Université Nangui Abrogoua, 02 BP 801 Abidjan 02, Côte d’Ivoire
2
UMR 5253, ICG Montpellier, Equipe AM2N, ENSCM, 8, rue de l'Ecole Normale, 34296 Montpellier cedex 5, France
3
INSERM U-1051, Institut des Neurosciences de Montpellier, 80 rue Augustin Fliche 34091 Montpellier, France
*
Author to whom correspondence should be addressed.
Sci. Pharm. 2014, 82(1), 171-176; https://doi.org/10.3797/scipharm.1307-08
Received: 9 July 2013 / Accepted: 19 November 2013 / Published: 19 November 2013

Abstract

The n-butanol extract of the roots of Glyphaea brevis was analysed. HPLC analysis suggested the presence of phenolic compounds like protocatechuic acid (PCA). The extract showed moderate cytotoxic activity against C6 glioma cells (EC50 > 1 mg/ml).
Keywords: Glyphaea brevis; HPLC; Protocatechuic acid; Cytotoxicity; C6 Cells Glyphaea brevis; HPLC; Protocatechuic acid; Cytotoxicity; C6 Cells

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MDPI and ACS Style

KONAN, K.M.; MAMYRBEKOVA-BEKRO, J.A.; BAKALARA, N.; VIRIEUX, D.; PIRAT, J.-L.; BEKRO, Y.-A. HPLC Analysis and Cytotoxicity of n-Butanol Extract from Glyphaea brevis Roots Against C6 Glioma Cells. Sci. Pharm. 2014, 82, 171-176. https://doi.org/10.3797/scipharm.1307-08

AMA Style

KONAN KM, MAMYRBEKOVA-BEKRO JA, BAKALARA N, VIRIEUX D, PIRAT J-L, BEKRO Y-A. HPLC Analysis and Cytotoxicity of n-Butanol Extract from Glyphaea brevis Roots Against C6 Glioma Cells. Scientia Pharmaceutica. 2014; 82(1):171-176. https://doi.org/10.3797/scipharm.1307-08

Chicago/Turabian Style

KONAN, Koffi Marcel, Janat Akhanovna MAMYRBEKOVA-BEKRO, Norbert BAKALARA, David VIRIEUX, Jean-Luc PIRAT, and Yves-Alain BEKRO. 2014. "HPLC Analysis and Cytotoxicity of n-Butanol Extract from Glyphaea brevis Roots Against C6 Glioma Cells" Scientia Pharmaceutica 82, no. 1: 171-176. https://doi.org/10.3797/scipharm.1307-08

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