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Scientia Pharmaceutica
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12 July 2010

Caffeine Nucleation Detection Using a Matrix of External Turbidity Probes: Bulk Video Imaging (BVI)

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1
ETH Zurich, Institute of Chemical and Bioengineering, Zurich, Switzerland
2
Loughborough University, Chemical Engineering Department, Loughborough, United Kingdom
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Abstract

The purpose of this work is two fold: it describes the proof of concept of the newly introduced bulk video imaging (BVI) method and it presents the nucleation detection in comparison with existing process analytical technologies (PAT) such as focused beam reflectance measurement (FBRM) and ultra violet/visible (UV/Vis) spectroscopy. [...]

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