Scientia Pharmaceutica is published by MDPI from Volume 84 Issue 3 (2016).
Articles in this Issue were published by another publisher in Open Access under a CC-BY (or CC-BY-NC-ND) licence.
Articles are hosted by MDPI on mdpi.com as a courtesy and upon agreement with Austrian Pharmaceutical Society (Österreichische Pharmazeutische Gesellschaft, ÖPhG).
Experimental and Mathematical Analysis of Hepatic Uptake
School of Engineering, University of Warwick, Coventry, CV4 7AL, United Kingdom
Departments of Pharmacy and Pharmacology, University of Bath, Bath, United Kingdom
DMPK Department, Astrazeneca, Alderley Park, Macclesfield, United Kingdom
Author to whom correspondence should be addressed.
Received: 12 July 2010 / Accepted: 12 July 2010 / Published: 12 July 2010
PDF [130 KB, uploaded 11 October 2016]
Abstract Introduction: To investigate the nonlinear kinetics of in vitro hepatic uptake the OATP substrate, Pitivastatin, was used as a probe. Experiments were conducted using freshly isolated rat hepatocytes, utilising the ‘oil spin’ methodology described by Hassen et al . [...]
This is an open access article distributed under the Creative Commons Attribution License
which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited (CC BY 4.0).
Share & Cite This Article
MDPI and ACS Style
GRANDJEAN, T.; LENCH, A.; YATES, J.W.T.; CHAPPELL, M.J.; O‘DONNELL, C.J. Experimental and Mathematical Analysis of Hepatic Uptake. Sci. Pharm. 2010, 78, 696.
GRANDJEAN T, LENCH A, YATES JWT, CHAPPELL MJ, O‘DONNELL CJ. Experimental and Mathematical Analysis of Hepatic Uptake. Scientia Pharmaceutica. 2010; 78(3):696.
GRANDJEAN, T.; LENCH, A.; YATES, J. W. T.; CHAPPELL, M. J.; O‘DONNELL, C. J. 2010. "Experimental and Mathematical Analysis of Hepatic Uptake." Sci. Pharm. 78, no. 3: 696.
Show more citation formats
Show less citations formats
[Return to top]
For more information on the journal statistics, click here
Multiple requests from the same IP address are counted as one view.