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Sci. Pharm.
Volume 78
Issue 3
10.3797/scipharm.cespt.8.PPAT07
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Scientia Pharmaceutica is published by MDPI from Volume 84 Issue 3 (2016). Previous articles were published by another publisher in Open Access under a CC-BY (or CC-BY-NC-ND) licence, and they are hosted by MDPI on mdpi.com as a courtesy and upon agreement with Austrian Pharmaceutical Society (Österreichische Pharmazeutische Gesellschaft, ÖPhG).
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Conference Report

Experimental and Mathematical Analysis of Hepatic Uptake

by
T. GRANDJEAN
1,*,
A. LENCH
2,
J. W. T. YATES
3,
M. J. CHAPPELL
1 and
C. J. O‘DONNELL
3
1
School of Engineering, University of Warwick, Coventry, CV4 7AL, United Kingdom
2
Departments of Pharmacy and Pharmacology, University of Bath, Bath, United Kingdom
3
DMPK Department, Astrazeneca, Alderley Park, Macclesfield, United Kingdom
*
Author to whom correspondence should be addressed.
Sci. Pharm. 2010, 78(3), 696; https://doi.org/10.3797/scipharm.cespt.8.PPAT07
Submission received: 12 July 2010 / Accepted: 12 July 2010 / Published: 12 July 2010
Versions Notes

Abstract

Introduction: To investigate the nonlinear kinetics of in vitro hepatic uptake the OATP substrate, Pitivastatin, was used as a probe. Experiments were conducted using freshly isolated rat hepatocytes, utilising the ‘oil spin’ methodology described by Hassen et al [1]. [...]

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MDPI and ACS Style

GRANDJEAN, T.; LENCH, A.; YATES, J.W.T.; CHAPPELL, M.J.; O‘DONNELL, C.J. Experimental and Mathematical Analysis of Hepatic Uptake. Sci. Pharm. 2010, 78, 696. https://doi.org/10.3797/scipharm.cespt.8.PPAT07

AMA Style

GRANDJEAN T, LENCH A, YATES JWT, CHAPPELL MJ, O‘DONNELL CJ. Experimental and Mathematical Analysis of Hepatic Uptake. Scientia Pharmaceutica. 2010; 78(3):696. https://doi.org/10.3797/scipharm.cespt.8.PPAT07

Chicago/Turabian Style

GRANDJEAN, T., A. LENCH, J. W. T. YATES, M. J. CHAPPELL, and C. J. O‘DONNELL. 2010. "Experimental and Mathematical Analysis of Hepatic Uptake" Scientia Pharmaceutica 78, no. 3: 696. https://doi.org/10.3797/scipharm.cespt.8.PPAT07

APA Style

GRANDJEAN, T., LENCH, A., YATES, J. W. T., CHAPPELL, M. J., & O‘DONNELL, C. J. (2010). Experimental and Mathematical Analysis of Hepatic Uptake. Scientia Pharmaceutica, 78(3), 696. https://doi.org/10.3797/scipharm.cespt.8.PPAT07

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