NF-κB Inhibitory Activities of the Methanol Extracts and some Constituents therein of some Vietnamese Medicinal Plants

NAM, Nguyen H.; JAE, You Y.

doi:10.3797/scipharm.0903-15

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Article

14 May 2009

11 Pages

NF-κB Inhibitory Activities of the Methanol Extracts and some Constituents therein of some Vietnamese Medicinal Plants

and

Department of Pharmaceutical Chemistry, Hanoi University of Pharmacy, 13-15 Le Thanh Tong, Hanoi, Vietnam

Department of Chemistry, University of South Dakota, South Dakota, USA

Author to whom correspondence should be addressed.

Sci. Pharm.2009, 77(2), 389-400;https://doi.org/10.3797/scipharm.0903-15

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Abstract

Eighty-seven methanol extracts of medicinal plants, most of them are currently used in Vietnamese oriental medicine, were screened for NF-κB inhibitory activity. Seven methanol extracts showed strong to moderate inhibitory activity. These include the extracts of Crinum latifolium (leaves), Evodia rutaecarpa (fruits), Polygonum cuspidatum (rhizoma), Perilla ocymoides (leaves), Rubia cordifolia (leaves), Scutellaria barbata (leaves) and Sparganium stenophyllum (leaves). The NF-κB inhibitory activities of several metabolites isolated from some of these plants were also reported.

Keywords:

NF-κB Inhibitory Activity; Screening; Medicinal Plants

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