2009 June - 13 articles
Eighty-seven methanol extracts of medicinal plants, most of them are currently used in Vietnamese oriental medicine, were screened for NF-κB inhibitory activity. Seven methanol extracts showed strong to moderate inhibitory activity. These include the...
The treatment for chronic anal fissure (CAF) has undergone a transformation in recent years from surgical to medical. Both the approaches share the common goal of reducing the spasm of anal sphincter. Though surgical treatment has a high success rate...
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Massage of essential oils is increasing being used for the improvement of the quality of life and for the relief of various symptoms in patients, but scientific evaluation of the effects of fragrances in humans is rather scarce. The aim of this study...
Epinephrine and non-epinephrine are major endogenous catecholamines which are known as neurotransmitter. The plasma levels of catecholamines are significant markers of several neuro-endocrine disorders and autonomic nervous system disorders. A method...
An improved pegylated liposomal formulation of docetaxel has been developed with the purpose of improving the docetaxel solubility without any need to use tween80 that is responsible for hypersensitivities following administration. Liposomes all had...
The hydrazide-hydrazone derivative 1 was formed through the reaction of cyanoacetic acid hydrazide with 2-acetylfuran. Compound 1 underwent a series of hetrocyclization reactions through its reaction with different chemical reagents to produce arylid...
The present study describes development and in vitro evaluation of budesonide microparticles prepared by spray drying for delivering drug directly to lungs via dry powder inhaler. This paper introduces new formulations for pharmaceutical applications...
In the present work a new indomethacin (IND) self-nanoemulsifying drug delivery formulation (SNEDDF) have been prepared to enhance its dissolution which in turn could provide a better chance for IND oral absorption. IND SNEDDF have been prepared usin...
Methods to improve patient’s compliance have always attracted scientists towards the development of fancy oral drug delivery systems. Among them, mouth dissolving drug delivery systems (MDDDS) have acquired an important position in the market by over...
Mouth dissolving tablets are well established dosage forms available in the market. The numerous advantages that they offer to the patients in terms of compliance as well as to the manufacturers in terms of huge revenues by line extension of products...
[67Ga]labeled 2-acetylpyridine 4,4-dimethylthiosemicarbazone ([67Ga]- [APTSM2]2+) was prepared using freshly prepared [67Ga]GaCl3 and 2-acetylpyridine 4,4-dimethylthiosemicarbazone (APTSM2) for 30 min at 90°C (radiochemical purity: >97% ITLC, >...
Pluronic F68 is a surfactant which can inhibit CYP3A4, an enzyme responsible for hepatic metabolism of many drugs including itraconazole. This study investigated the effect of incorporation of Pluronic F68 as a ternary component in solid dispersions...
