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Kurzfassungen der Vorträge und Poster der 21. Wissenschaftlichen Tagung der Österreichischen Pharmazeutischen Gesellschaft (ÖPhG), 16. bis 18. April 2009, Wien, Österreich
- Scientia Pharmaceutica Editorial Office
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March 2009 - 14 articles
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Three dehydrogenases – (R)-alcohol dehydrogenase from L. kefir, (S)-aromatic alcohol dehydrogenase from T. sp. and (S)-alcohol dehydrogenase from T. brockii – were tested for the preparation of enantiopure hydroxyl metabolites of pentoxifylline (PTX)...
The marine benzo[c][2,7]naphthyridine alkaloid subarine is prepared in 4 steps, starting from commercially available 1,10-phenanthroline, via oxidative cleavage to the bipyridine-dicarboxylate, conversion to the mono(2-iodoanilide), and radical cycli...
During the synthesis of Sparfloxacin, a fluoroquinolone antibiotic drug, an unknown impurity (SF5-IMP) was identified in the fifth stage of the synthetic process. The impurity has been isolated from the mother liquor of intermediate SF5. The mother l...
Antioxidative and anti-inflammatory activities of Ganoderma lucidum (Curt.: Fr.) P. Karst. (Aphyllophoromycetideae) from tropical South India were investigated. The chloroform extract of the mushroom showed marked free radical scavenging activities....
In the current study a quantitative structure activity relationship approach using sequential multiple linear regression analysis was applied to a series of 2-alkyl- 4-(biphenylylmethoxy)quinolines as angiotensin II (Ang II) receptor antagonists by u...
The freezing process as well as cryostorage may induce molecular and cellular changes due to osmotic stress. Currently, standard protocols for cryopreservation of mammalian cells recommend slow freezing and rapid thawing to avoid intracellular ice cr...
Artemisinin, a sesquiterpene lactone, is the active antimalarial constituent of Artemisia annua. Several fungal strains Saccharomyces cerevisiae, Aspergillus flavus, Aspergillus niger and Picchia pastoris were used to biotransform artemisinin. Among...
Plantago major has been used in traditional medicine for the treatment of various diseases. In order to evaluate the quality of P. major, a simple, rapid and accurate high-performance liquid chromatography (HPLC) method was developed for the assessme...
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