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Article

Preservative Evaluation of Caprylic Acid Derivatives in Aluminium Hydroxide Gel – USP

by
Jasmine CHAUDHARY
1,
Archana K. RAJPAL
1,
Vikramjeet JUDGE
1,
Rakesh NARANG
1 and
Balasubramanian NARASIMHAN
2,*
1
Department of Pharmaceutical Sciences, Guru Jambheshwar University of Science and Technology, Hisar-125001, India
2
Faculty of Pharmaceutical Sciences, Maharshi Dayanand University, Rohtak-124001, India
*
Author to whom correspondence should be addressed.
Sci. Pharm. 2008, 76(3), 533-540; https://doi.org/10.3797/scipharm.0807-24
Submission received: 30 July 2008 / Accepted: 1 September 2008 / Published: 2 September 2008

Abstract

The potential derivatives of caprylic acid were subjected to preservative efficacy testing in Aluminium Hydroxide Gel – USP using Staphylococcus aureus MTCC 2901, Bacillus subtilis MTCC 2063, and Escherichia coli MTCC 1652 as representative challenging microorganisms for antimicrobial effectiveness testing as per USP 2004. The caprylic acid derivative, capryl hydrazide exhibited better preservative efficacy than caprylic acid as well as the standard preservatives, methyl paraben and propyl paraben.
Keywords: Caprylic acid; Capryl hydrazide; p-Chlorocaprylanilide; Preservative efficacy Caprylic acid; Capryl hydrazide; p-Chlorocaprylanilide; Preservative efficacy

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MDPI and ACS Style

CHAUDHARY, J.; RAJPAL, A.K.; JUDGE, V.; NARANG, R.; NARASIMHAN, B. Preservative Evaluation of Caprylic Acid Derivatives in Aluminium Hydroxide Gel – USP. Sci. Pharm. 2008, 76, 533-540. https://doi.org/10.3797/scipharm.0807-24

AMA Style

CHAUDHARY J, RAJPAL AK, JUDGE V, NARANG R, NARASIMHAN B. Preservative Evaluation of Caprylic Acid Derivatives in Aluminium Hydroxide Gel – USP. Scientia Pharmaceutica. 2008; 76(3):533-540. https://doi.org/10.3797/scipharm.0807-24

Chicago/Turabian Style

CHAUDHARY, Jasmine, Archana K. RAJPAL, Vikramjeet JUDGE, Rakesh NARANG, and Balasubramanian NARASIMHAN. 2008. "Preservative Evaluation of Caprylic Acid Derivatives in Aluminium Hydroxide Gel – USP" Scientia Pharmaceutica 76, no. 3: 533-540. https://doi.org/10.3797/scipharm.0807-24

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