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Sci. Pharm. 2008, 76(3), 533-540; https://doi.org/10.3797/scipharm.0807-24 (registering DOI)
Preservative Evaluation of Caprylic Acid Derivatives in Aluminium Hydroxide Gel – USP
Department of Pharmaceutical Sciences, Guru Jambheshwar University of Science and Technology, Hisar-125001, India
Faculty of Pharmaceutical Sciences, Maharshi Dayanand University, Rohtak-124001, India
Author to whom correspondence should be addressed.
Received: 30 July 2008 / Accepted: 1 September 2008 / Published: 2 September 2008
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Abstract The potential derivatives of caprylic acid were subjected to preservative efficacy testing in Aluminium Hydroxide Gel – USP using Staphylococcus aureus MTCC 2901, Bacillus subtilis MTCC 2063, and Escherichia coli MTCC 1652 as representative challenging microorganisms for antimicrobial effectiveness testing as per USP 2004. The caprylic acid derivative, capryl hydrazide exhibited better preservative efficacy than caprylic acid as well as the standard preservatives, methyl paraben and propyl paraben.
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CHAUDHARY, J.; RAJPAL, A.K.; JUDGE, V.; NARANG, R.; NARASIMHAN, B. Preservative Evaluation of Caprylic Acid Derivatives in Aluminium Hydroxide Gel – USP. Sci. Pharm. 2008, 76, 533-540.
CHAUDHARY J, RAJPAL AK, JUDGE V, NARANG R, NARASIMHAN B. Preservative Evaluation of Caprylic Acid Derivatives in Aluminium Hydroxide Gel – USP. Scientia Pharmaceutica. 2008; 76(3):533-540.
CHAUDHARY, Jasmine; RAJPAL, Archana K.; JUDGE, Vikramjeet; NARANG, Rakesh; NARASIMHAN, Balasubramanian. 2008. "Preservative Evaluation of Caprylic Acid Derivatives in Aluminium Hydroxide Gel – USP." Sci. Pharm. 76, no. 3: 533-540.
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