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Sci. Pharm.Scientia Pharmaceutica
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  • Scientia Pharmaceutica is published by MDPI from Volume 84 Issue 3 (2016). Previous articles were published by another publisher in Open Access under a CC-BY (or CC-BY-NC-ND) licence, and they are hosted by MDPI on mdpi.com as a courtesy and upon agreement with Austrian Pharmaceutical Society (Österreichische Pharmazeutische Gesellschaft, ÖPhG).
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  • Open Access

4 June 2002

9 Pages

Synthesis of new piperidine and cyclohexylamino-spiro derivatives as potential anticalcium agents

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1
Laboratori de Quimica Farmaceutica, Facultat de Farmacia, Universitat de Barcelona, Av. Diagonal 643, 08028 Barcelona (Spain)
2
lnstitut de Chimie Organique et Analytique associe au CNRS, Universite d'orleans, BP 6957,45067 Orleans Cedex 2 (France).
3
UCB Pharma, Pharmaceutical Sector, Chemin du Foriest, B-1420 Braine-L'Alleud (Belgique)
4
Laboratoire RL-CERM, ZI La Varenne, rue H. Goudier, 63203 Riom, Cedex (France)
Sci. Pharm.2002, 70(2), 177-185;https://doi.org/10.3797/scipharm.aut-02-19
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Simple Summary

The synthesis of new 1,3-benzodioxolo and 1,4- benzodioxan spiro derivatives containing a piperidine (4-6) or cyclohexylamino (7-8) group have been described. These compounds exhibit in vitro a moderate anticalcium activity.

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Note: In lieu of an abstract, this is an excerpt from the first page.

The spiropiperidine derivatives have considerable importance in pharmaceutical chemistry due to their effects on different biological systems [...]

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