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Sci. Pharm.
Volume 70
Issue 2
10.3797/scipharm.aut-02-19
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Scientia Pharmaceutica is published by MDPI from Volume 84 Issue 3 (2016). Previous articles were published by another publisher in Open Access under a CC-BY (or CC-BY-NC-ND) licence, and they are hosted by MDPI on mdpi.com as a courtesy and upon agreement with Austrian Pharmaceutical Society (Österreichische Pharmazeutische Gesellschaft, ÖPhG).
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Article

Synthesis of new piperidine and cyclohexylamino-spiro derivatives as potential anticalcium agents

by
Sánchez Isabel
1,
Pujol Maria Dolors
1,*,
Guillaumet Gérald
2,
Massingham Roy
3 and
Monteil André
4
1
Laboratori de Quimica Farmaceutica, Facultat de Farmacia, Universitat de Barcelona, Av. Diagonal 643, 08028 Barcelona (Spain)
2
lnstitut de Chimie Organique et Analytique associe au CNRS, Universite d'orleans, BP 6957,45067 Orleans Cedex 2 (France).
3
UCB Pharma, Pharmaceutical Sector, Chemin du Foriest, B-1420 Braine-L'Alleud (Belgique)
4
Laboratoire RL-CERM, ZI La Varenne, rue H. Goudier, 63203 Riom, Cedex (France)
*
Author to whom correspondence should be addressed.
Sci. Pharm. 2002, 70(2), 177-185; https://doi.org/10.3797/scipharm.aut-02-19
Submission received: 11 February 2002 / Revised: 4 March 2002 / Accepted: 4 March 2002 / Published: 4 June 2002
Versions Notes

Simple Summary

The synthesis of new 1,3-benzodioxolo and 1,4- benzodioxan spiro derivatives containing a piperidine (4-6) or cyclohexylamino (7-8) group have been described. These compounds exhibit in vitro a moderate anticalcium activity.

Excerpt

Note: In lieu of an abstract, this is an excerpt from the first page.

The spiropiperidine derivatives have considerable importance in pharmaceutical chemistry due to their effects on different biological systems [...]
Keywords: Spiro compounds, 1,3-benzodioxole, 1,3-benzodioxan, anticalcium activity Spiro compounds, 1,3-benzodioxole, 1,3-benzodioxan, anticalcium activity

Share and Cite

MDPI and ACS Style

Isabel, S.; Maria Dolors, P.; Gérald, G.; Roy, M.; André, M. Synthesis of new piperidine and cyclohexylamino-spiro derivatives as potential anticalcium agents. Sci. Pharm. 2002, 70, 177-185. https://doi.org/10.3797/scipharm.aut-02-19

AMA Style

Isabel S, Maria Dolors P, Gérald G, Roy M, André M. Synthesis of new piperidine and cyclohexylamino-spiro derivatives as potential anticalcium agents. Scientia Pharmaceutica. 2002; 70(2):177-185. https://doi.org/10.3797/scipharm.aut-02-19

Chicago/Turabian Style

Isabel, Sánchez, Pujol Maria Dolors, Guillaumet Gérald, Massingham Roy, and Monteil André. 2002. "Synthesis of new piperidine and cyclohexylamino-spiro derivatives as potential anticalcium agents" Scientia Pharmaceutica 70, no. 2: 177-185. https://doi.org/10.3797/scipharm.aut-02-19

APA Style

Isabel, S., Maria Dolors, P., Gérald, G., Roy, M., & André, M. (2002). Synthesis of new piperidine and cyclohexylamino-spiro derivatives as potential anticalcium agents. Scientia Pharmaceutica, 70(2), 177-185. https://doi.org/10.3797/scipharm.aut-02-19

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