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Biosensors, Volume 14, Issue 9

2024 September - 45 articles

Cover Story: Random lasers (RLs) are a singular family of lasers in which the feedback comes from recurrent scattering events instead of the trapping of light in a mirror resonator. This allows for the obtention of laser light while forgoing the need for cavity building. Also, since scattering is what produces the phenomenon, the emission is highly sensitive to the scattering characteristics of its own lasing medium. In this paper, we present, for the first time, the obtention of RLs from human whole blood and blood components as scatterers, using a commercial laser dye for amplification. Its sensing potential is also showcased through an observational case study, in which a multivariate statistical analysis of the RL spectra distinguished the blood of Chronic Lymphocytic Leukaemia patients from that of healthy individuals. View this paper
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Articles (45)

  • Article
  • Open Access
5 Citations
2,779 Views
11 Pages

Improved Glycemic Control during a One-Week Adventure Camp in Adolescents with Type 1 Diabetes—The DIACAMP Study

  • Antonia-Therese Kietaibl,
  • Faisal Aziz,
  • Eva Wurm,
  • Celine Tomka,
  • Othmar Moser,
  • Thomas R. Pieber,
  • Elke Fröhlich-Reiterer,
  • Peter Fasching,
  • Julia K. Mader and
  • Felix Aberer
  • + 1 author

21 September 2024

Adolescence remains a crucial age associated with diabetes distress in individuals living with type 1 diabetes (T1D). The Austrian organization “Diabär” regularly hosts a one-week adventure camp for adolescents (12–18 years) living with T1D. The camp...

  • Article
  • Open Access
2,270 Views
14 Pages

Development of a Modular miRNA-Responsive Biosensor for Organ-Specific Evaluation of Liver Injury

  • Xinxin Zhang,
  • Tingting Wang,
  • Xiangqing Fan,
  • Meixia Wang,
  • Zhixi Duan,
  • Fang He,
  • Hong-Hui Wang and
  • Zhihong Li

20 September 2024

MicroRNAs (miRNAs) are increasingly being considered essential diagnostic biomarkers and therapeutic targets for multiple diseases. In recent years, researchers have emphasized the need to develop probes that can harness extracellular miRNAs as input...

  • Review
  • Open Access
3 Citations
6,732 Views
22 Pages

Microfluidic Gastrointestinal Cell Culture Technologies—Improvements in the Past Decade

  • Adrian J. T. Teo,
  • Siu-Kin Ng,
  • Kaydeson Khoo,
  • Sunny Hei Wong and
  • King Ho Holden Li

19 September 2024

Gastrointestinal cell culture technology has evolved in the past decade with the integration of microfluidic technologies, bringing advantages with greater selectivity and cost effectiveness. Herein, these technologies are sorted into three categorie...

  • Article
  • Open Access
4 Citations
2,363 Views
11 Pages

A Novel Ferrocene-Linked Thionine as a Dual Redox Mediator for the Electrochemical Detection of Dopamine and Hydrogen Peroxide

  • Manikandan Palinci Nagarajan,
  • Manikandan Ramalingam,
  • Ilakeya Subbiah Arivuthilagam,
  • Vishwa Paramaguru,
  • Md. Mahbubur Rahman,
  • Jongdeok Park,
  • Francis Kwaku Asiam,
  • Byungjik Lee,
  • Kwang Pyo Kim and
  • Jae-Joon Lee

19 September 2024

We introduce a novel dual redox mediator synthesized by covalently linking ferrocene dicarboxylic acid (FcDA) and thionine (TH) onto a pre-treated glassy carbon electrode. This unique structure significantly enhances the electro-oxidation of dopamine...

  • Editorial
  • Open Access
1 Citations
2,417 Views
5 Pages

Editorial to the Special Issue “Advances in Optical Biosensors and Chemical Sensors”

  • Flavio Esposito,
  • Stefania Campopiano and
  • Agostino Iadicicco

19 September 2024

Optical biosensors and optical chemical sensors are innovative analytical tools that utilize light-based techniques to detect and quantify a plethora of biological and chemical substances [...]

  • Article
  • Open Access
2 Citations
2,012 Views
14 Pages

Ultrasensitive Electrochemical Biosensors Based on Allosteric Transcription Factors (aTFs) for Pb2+ Detection

  • Ningkang Yu,
  • Chen Zhao,
  • Xiaodan Kang,
  • Cheng Zhang,
  • Xi Zhang,
  • Chenyu Li,
  • Shang Wang,
  • Bin Xue,
  • Xiaobo Yang and
  • Zhiqiang Shen
  • + 3 authors

18 September 2024

Exposure to Pb2+ in the environment, especially in water, poses a significant threat to human health and urgently necessitates the development of highly sensitive Pb2+ detection methods. In this study, we have integrated the high sensitivity of elect...

  • Article
  • Open Access
11 Citations
3,770 Views
12 Pages

18 September 2024

The rapid and sensitive detection of bacterial contaminants using low-cost and portable point-of-need (PoN) biosensors has gained significant interest in water quality monitoring. Cell-imprinted polymers (CIPs) are emerging as effective and inexpensi...

  • Article
  • Open Access
1 Citations
4,101 Views
20 Pages

Salmonella Detection in Food Using a HEK-hTLR5 Reporter Cell-Based Sensor

  • Esma Eser,
  • Victoria A. Felton,
  • Rishi Drolia and
  • Arun K. Bhunia

18 September 2024

The development of a rapid, sensitive, specific method for detecting foodborne pathogens is paramount for supplying safe food to enhance public health safety. Despite the significant improvement in pathogen detection methods, key issues are still ass...

  • Review
  • Open Access
4 Citations
3,715 Views
19 Pages

14 September 2024

Current diagnostic and prognostic tests for prostate cancer require specialised laboratories and have low specificity for prostate cancer detection. As such, recent advancements in electrochemical devices for point of care (PoC) prostate cancer detec...

  • Article
  • Open Access
6 Citations
2,955 Views
11 Pages

14 September 2024

Lactate is a critical regulatory factor secreted by tumors, influencing tumor development, metastasis, and clinical prognosis. Precise analysis of tumor-cell-secreted lactate is pivotal for early cancer diagnosis. This study describes a paper-based m...

  • Article
  • Open Access
3 Citations
1,706 Views
12 Pages

Analysis of Random Lasing in Human Blood

  • Sergio de Armas-Rillo,
  • Beatriz Abdul-Jalbar,
  • Josmar Salas-Hernández,
  • Jose María Raya-Sánchez,
  • Tomás González-Hernández and
  • Fernando Lahoz

13 September 2024

Random lasing (RL) is an optical phenomenon that arises from the combination of light amplification with optical feedback through multiple scattering events. In this paper, we present our investigations of RL generation from human blood samples. We t...

  • Communication
  • Open Access
7 Citations
2,642 Views
10 Pages

13 September 2024

Terahertz (THZ) spectroscopy has emerged as a superior label-free sensing technology in the detection, identification, and quantification of biomolecules in various biological samples. However, the limitations in identification and discrimination sen...

  • Article
  • Open Access
7 Citations
3,032 Views
12 Pages

Investigation of Interferences of Wearable Sensors with Plant Growth

  • Xiao Xiao,
  • Xinyue Liu,
  • Yanbo Liu,
  • Chengjin Tu,
  • Menglong Qu,
  • Jingjing Kong,
  • Yongnian Zhang and
  • Cheng Zhang

11 September 2024

Plant wearable sensors have shown exceptional promise in continuously monitoring plant health. However, the potential adverse effects of these sensors on plant growth remain unclear. This study systematically quantifies wearable sensors’ interf...

  • Article
  • Open Access
1,815 Views
16 Pages

2PP-Hydrogel Covered Electrodes to Compensate for Media Effects in the Determination of Biomass in a Capillary Wave Micro Bioreactor

  • Sven Meinen,
  • Steffen Brinkmann,
  • Kevin Viebrock,
  • Bassant Elbardisy,
  • Henning Menzel,
  • Rainer Krull and
  • Andreas Dietzel

9 September 2024

Microbioreactors increase information output in biopharmaceutical screening applications because they can be operated in parallel without consuming large quantities of the pharmaceutical formulations being tested. A capillary wave microbioreactor (cw...

  • Article
  • Open Access
2,815 Views
18 Pages

Investigation of a Camera-Based Contactless Pulse Oximeter with Time-Division Multiplex Illumination Applied on Piglets for Neonatological Applications

  • René Thull,
  • Sybelle Goedicke-Fritz,
  • Daniel Schmiech,
  • Aly Marnach,
  • Simon Müller,
  • Christina Körbel,
  • Matthias W. Laschke,
  • Erol Tutdibi,
  • Nasenien Nourkami-Tutdibi and
  • Andreas R. Diewald
  • + 3 authors

9 September 2024

(1) Objective: This study aims to lay a foundation for noncontact intensive care monitoring of premature babies. (2) Methods: Arterial oxygen saturation and heart rate were measured using a monochrome camera and time-division multiplex controlled lig...

  • Article
  • Open Access
4 Citations
2,238 Views
12 Pages

9 September 2024

Estrogenic chemicals are widely distributed and structurally diverse. They primarily disrupt estrogen-related metabolism in animals or humans by mimicking the agonistic receptor effects of natural estrogens, thereby influencing the transcription of e...

  • Article
  • Open Access
7 Citations
3,682 Views
17 Pages

6 September 2024

The liver has many important functions, including the biotransformation of drugs and detoxification of the human organism. As such, it is also exposed to many harmful substances, which leads to disorders and diseases such as cirrhosis. For these reas...

  • Article
  • Open Access
4 Citations
2,705 Views
33 Pages

Microwave Technique for Linear Skull Fracture Detection—Simulation and Experimental Study Using Realistic Human Head Models

  • Mariella Särestöniemi,
  • Daljeet Singh,
  • Mikael von und zu Fraunberg and
  • Teemu Myllylä

6 September 2024

Microwave (MW) sensing is regarded as a promising technique for various medical monitoring and diagnostic applications due to its numerous advantages and the potential to be developed into a portable device for use outside hospital settings. The dete...

  • Review
  • Open Access
3 Citations
2,325 Views
14 Pages

6 September 2024

Plasmonic intragap nanostructures (PINs) have garnered intensive attention in Raman-related analysis due to their exceptional ability to enhance light–matter interactions. Although diverse synthetic strategies have been employed to create these...

  • Article
  • Open Access
6 Citations
2,988 Views
13 Pages

A Cost-Effective and Easy-to-Fabricate Conductive Velcro Dry Electrode for Durable and High-Performance Biopotential Acquisition

  • Jun Guo,
  • Xuanqi Wang,
  • Ruiyu Bai,
  • Zimo Zhang,
  • Huazhen Chen,
  • Kai Xue,
  • Chuang Ma,
  • Dawei Zang,
  • Erwei Yin and
  • Bowen Ji
  • + 1 author

6 September 2024

Compared with the traditional gel electrode, the dry electrode is being taken more seriously in bioelectrical recording because of its easy preparation, long-lasting ability, and reusability. However, the commonly used dry AgCl electrodes and silver...

  • Article
  • Open Access
7 Citations
2,668 Views
14 Pages

Comparative Analysis of QCM and Electrochemical Aptasensors for SARS-CoV-2 Detection

  • Katarína Nemčeková,
  • Jana Korčeková,
  • Veronika Svitková,
  • Denis Baraniak,
  • Michaela Domšicová,
  • Eva Melníková,
  • Michaela Hornychová,
  • Viktória Szebellaiová,
  • Miroslav Gál and
  • Alexandra Poturnayová

6 September 2024

The rapid and accurate detection of SARS-CoV-2, particularly its spike receptor-binding domain (S-RBD), was crucial for managing the COVID-19 pandemic. This study presents the development and optimization of two types of aptasensors: quartz crystal m...

  • Article
  • Open Access
3 Citations
3,354 Views
19 Pages

Enhancing Colorimetric Detection of Nucleic Acids on Nitrocellulose Membranes: Cutting-Edge Applications in Diagnostics and Forensics

  • Nidhi Subhashini,
  • Yannick Kerler,
  • Marcus M. Menger,
  • Olga Böhm,
  • Judith Witte,
  • Christian Stadler and
  • Alexander Griberman

5 September 2024

This study re-introduces a protein-free rapid test method for nucleic acids on paper based lateral flow assays utilizing special multichannel nitrocellulose membranes and DNA-Gold conjugates, achieving significantly enhanced sensitivity, easier proto...

  • Communication
  • Open Access
5 Citations
2,801 Views
9 Pages

5 September 2024

Recent advances in three-dimensional (3D) culturing and nanotechnology offer promising pathways to overcome the limitations of drug screening, particularly for tumors like neuroblastoma. In this study, we develop a high-throughput microfluidic chip t...

  • Article
  • Open Access
1 Citations
3,318 Views
14 Pages

5 September 2024

Mitochondria, crucial intracellular organelles, are central to energy metabolism, signal transduction, apoptosis, calcium homeostasis, and a myriad of other biological processes, making them a focal point in diverse research fields. The capacity to f...

  • Communication
  • Open Access
5 Citations
2,148 Views
9 Pages

The Assessment of Methyl Methanesulfonate Absorption by Amphipods from the Environment Using Lux-Biosensors

  • Uliana S. Novoyatlova,
  • Anna A. Kudryavtseva,
  • Sergey V. Bazhenov,
  • Anna A. Utkina,
  • Vadim V. Fomin,
  • Shamil A. Nevmyanov,
  • Bagila S. Zhoshibekova,
  • Maria A. Fedyaeva,
  • Mikhail Y. Kolobov and
  • Ilya V. Manukhov

5 September 2024

The ability of aquatic mesofauna representatives involved in trophic chains to sorb and accumulate toxicants is important for understanding the functioning of aquatic ecosystems and for fishing industry. This study investigated the capacity of marine...

  • Article
  • Open Access
3 Citations
2,068 Views
12 Pages

4 September 2024

Nanowell-based impedance-based label-free biosensors have demonstrated significant advantages in sensitivity, simplicity, and accuracy for detecting cancer biomarkers and macromolecules compared to conventional impedance-based biosensors. Although na...

  • Review
  • Open Access
14 Citations
4,997 Views
29 Pages

3 September 2024

Traditional drug development is a long and expensive process with high rates of failure. This has prompted the pharmaceutical industry to seek more efficient drug development frameworks, driving the emergence of organ-on-a-chip (OOC) based on microfl...

  • Article
  • Open Access
1 Citations
3,037 Views
14 Pages

Advanced Imaging Methodology in Bacterial Biofilms with a Fluorescent Enzymatic Sensor for pepN Activity

  • Javier Valverde-Pozo,
  • Jose M. Paredes,
  • María Eugenia García-Rubiño,
  • María Dolores Girón,
  • Rafael Salto,
  • Jose M. Alvarez-Pez and
  • Eva M. Talavera

3 September 2024

This research explores the use of the pepN activity fluorescent sensor DCM-Ala in bacterial biofilms, emphasizing its significance due to the critical role of biofilms in various biological processes. Advanced imaging techniques were employed to visu...

  • Systematic Review
  • Open Access
9 Citations
6,564 Views
24 Pages

2 September 2024

The gut microbiome is shaped early in life by dietary and lifestyle factors. Specific compounds in the gut affect the growth of different bacterial species and the production of beneficial or harmful byproducts. Dysbiosis of the gut microbiome has be...

  • Review
  • Open Access
8 Citations
6,196 Views
55 Pages

Recent Progress in Biosensors for Depression Monitoring—Advancing Personalized Treatment

  • Jiaju Yin,
  • Xinyuan Jia,
  • Haorong Li,
  • Bingchen Zhao,
  • Yi Yang and
  • Tian-Ling Ren

30 August 2024

Depression is currently a major contributor to unnatural deaths and the healthcare burden globally, and a patient’s battle with depression is often a long one. Because the causes, symptoms, and effects of medications are complex and highly indi...

  • Communication
  • Open Access
5,349 Views
10 Pages

Optical Interferometric Device for Rapid and Specific Detection of Biological Cells

  • Sándor Valkai,
  • Dániel Petrovszki,
  • Zsombor Fáskerti,
  • Margaréta Baumgärtner,
  • Brigitta Biczók,
  • Kira Dakos,
  • Kevin Dósa,
  • Berill B. Kirner,
  • Anna E. Kocsis and
  • András Dér
  • + 2 authors

29 August 2024

Here, we report a rapid and accurate optical method for detecting cells from liquid samples in a label-free manner. The working principle of the method is based on the interference of parts of a conical laser beam, coming from a single-mode optical f...

  • Review
  • Open Access
19 Citations
5,356 Views
28 Pages

28 August 2024

Flexible electrochemical sensors can adhere to any bendable surface with conformal contact, enabling continuous data monitoring without compromising the surface’s dynamics. Among various materials that have been explored for flexible electronic...

  • Review
  • Open Access
6 Citations
3,477 Views
22 Pages

27 August 2024

Point-of-care testing (POCT) is a contemporary diagnostic approach characterized by its user-friendly nature, cost efficiency, environmental compatibility, and lack of reliance on professional experts. Therefore, it is widely used in clinical diagnos...

  • Article
  • Open Access
2 Citations
2,821 Views
15 Pages

A Novel Personalized Strategy for Hip Joint Flexion Assistance Based on Human Physiological State

  • Beixian Wu,
  • Chunjie Chen,
  • Sheng Wang,
  • Hui Chen,
  • Zhuo Wang,
  • Yao Liu,
  • Tingwei He,
  • Jiale Zhang and
  • Xinyu Wu

27 August 2024

Soft exosuits have emerged as potent assistive tools for walking support and rehabilitation training. However, most existing soft exosuit systems rely on preset assistance modes, which may not accurately align with individual physiological states and...

  • Review
  • Open Access
20 Citations
11,367 Views
37 Pages

27 August 2024

Dielectrophoresis (DEP) is an advanced microfluidic manipulation technique that is based on the interaction of polarized particles with the spatial gradient of a non-uniform electric field to achieve non-contact and highly selective manipulation of p...

  • Article
  • Open Access
3 Citations
4,392 Views
24 Pages

Overcoming Limited Access to Virus Infection Rapid Testing: Development of a Lateral Flow Test for SARS-CoV-2 with Locally Available Resources

  • Estefanía S. Peri Ibáñez,
  • Agostina Mazzeo,
  • Carolina Silva,
  • Maria Juliana Juncos,
  • Guadalupe S. Costa Navarro,
  • Horacio M. Pallarés,
  • Virginia J. Wolos,
  • Gabriel L. Fiszman,
  • Silvia L. Mundo and
  • Daiana A. Capdevila
  • + 6 authors

27 August 2024

The COVID-19 pandemic highlighted testing inequities in developing countries. Lack of lateral flow test (LFT) manufacturing capacity was a major COVID-19 response bottleneck in low- and middle-income regions. Here we report the development of an open...

  • Review
  • Open Access
7 Citations
4,484 Views
24 Pages

Recent Advances in Natural-Polymer-Based Hydrogels for Body Movement and Biomedical Monitoring

  • Jing Liu,
  • Saisai Li,
  • Shuoze Li,
  • Jinyue Tian,
  • Hang Li,
  • Zhifeng Pan,
  • Lijun Lu and
  • Yanchao Mao

27 August 2024

In recent years, the interest in medical monitoring for human health has been rapidly increasing due to widespread concern. Hydrogels are widely used in medical monitoring and other fields due to their excellent mechanical properties, electrical cond...

  • Article
  • Open Access
2 Citations
2,594 Views
15 Pages

Microscale Humidity Sensor Based on Iron-Coated Elaters of Equisetum Spores

  • Yanting Liu,
  • Zhexuan Lin,
  • Xiaochun Li,
  • Rui Huang,
  • Xuewan Wu,
  • Ruyi Deng and
  • Kaisong Yuan

26 August 2024

Humidity sensors deeply influence human manufacturing production and daily life, while researchers generally focus on developing humidity sensors with higher stability, higher linearity, rapid response time, etc. Yet, few people discuss measuring hum...

  • Article
  • Open Access
7 Citations
2,990 Views
22 Pages

Comparative Study of Fluorescence Emission of Fisetin, Luteolin and Quercetin Powders and Solutions: Further Evidence of the ESIPT Process

  • Alexandra Deriabina,
  • Tatiana Prutskij,
  • Hector Daniel Morales Ochoa,
  • Esteban Delgado Curiel and
  • Veranda Palacios Corte

26 August 2024

Fisetin and Luteolin are important flavonoids produced in plants and known for their antioxidant, anti-inflammatory, neuroprotective, and analgesic properties. They are also good candidates for different types of biosensors. The model used to describ...

  • Article
  • Open Access
4 Citations
3,018 Views
14 Pages

Enhancing Heavy Metal Detection through Electrochemical Polishing of Carbon Electrodes

  • Sanjeev Billa,
  • Rohit Boddu,
  • Shabnam Siddiqui and
  • Prabhu U. Arumugam

24 August 2024

Our research addresses the pressing need for environmental sensors capable of large-scale, on-site detection of a wide array of heavy metals with highly accurate sensor metrics. We present a novel approach using electrochemically polished (ECP) carbo...

  • Article
  • Open Access
7 Citations
2,314 Views
9 Pages

Core–Shell PEDOT-PVDF Nanofiber-Based Ammonia Gas Sensor with Robust Humidity Resistance

  • Shenghao Xiao,
  • Mengjie Hu,
  • Yinhui Hong,
  • Mengjia Hu,
  • Tongtong Sun and
  • Dajing Chen

24 August 2024

Current ammonia sensors exhibit cross-sensitivity to water vapor, leading to false alarms. We developed a core–shell nanofiber (CSNF) structure to address these issues, using conductive poly(3,4-ethylenedioxythiophene) (PEDOT) as the core and h...

  • Article
  • Open Access
5 Citations
2,943 Views
16 Pages

A Finger-Actuated Sample-Dosing Capillary-Driven Microfluidic Device for Loop-Mediated Isothermal Amplification

  • Xuan Le,
  • Jianxiong Chan,
  • James McMahon,
  • Jessica A. Wisniewski,
  • Anna Coldham,
  • Tuncay Alan and
  • Patrick Kwan

23 August 2024

Loop-mediated isothermal amplification (LAMP) has attracted significant attention for rapid and accurate point-of-care diagnostics. However, integrating sample introduction, lysis, amplification, and detection steps into an easy-to-use, disposable sy...

  • Article
  • Open Access
1 Citations
2,672 Views
19 Pages

23 August 2024

This study examined applications of polarized evanescent guided wave surface-enhanced Raman spectroscopy to determine the binding and orientation of small molecules and ligand-modified nanoparticles, and the relevance of this technique to lab-on-a-ch...

  • Article
  • Open Access
3 Citations
2,458 Views
14 Pages

Fabrication of Patterned Magnetic Particles in Microchannels and Their Application in Micromixers

  • Tianhao Li,
  • Chen Yang,
  • Zihao Shao,
  • Ya Chen,
  • Jiahui Zheng,
  • Jun Yang and
  • Ning Hu

23 August 2024

Due to the extremely low Reynolds number, the mixing of substances in laminar flow within microfluidic channels primarily relies on slow intermolecular diffusion, whereas various rapid reaction and detection requirements in lab-on-a-chip applications...

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Biosensors - ISSN 2079-6374