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Biosensors, Volume 13, Issue 8

August 2023 - 77 articles

Cover Story: An injectable far-red fluorescence intensity-based glucose sensing assay based on solvatochromism, the reversible change in the emission spectrum dependent on the polarity of the solvent, was designed and created with a composition of PEGylated ConA and Cy5.5-labeled mannotetraose. The assay shows a linear change in fluorescence intensity at peak emission within the physiological glucose range (25 - 350 mg/dL) with a percent MARD of 12.7%. A comparison of percent change in the peak emission intensity of the assay placed beneath rat skin samples with three pigmentations (light, medium, and dark) of the same thickness (~2.1 mm), without glucose present, showed the percent change in peak emission intensity was not significantly different (p < 0.05) for the different pigmentations. Illustration created with BioRender.com. View this paper
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Articles (77)

  • Review
  • Open Access
17 Citations
7,246 Views
35 Pages

Insole Systems for Disease Diagnosis and Rehabilitation: A Review

  • Zhiyuan Zhang,
  • Yanning Dai,
  • Zhenyu Xu,
  • Nicolas Grimaldi,
  • Jiamu Wang,
  • Mufan Zhao,
  • Ruilin Pang,
  • Yueming Sun,
  • Shuo Gao and
  • Hu Boyi

21 August 2023

Some chronic diseases, including Parkinson’s disease (PD), diabetic foot, flat foot, stroke, elderly falling, and knee osteoarthritis (KOA), are related to orthopedic organs, nerves, and muscles. The interaction of these three parts will genera...

  • Article
  • Open Access
5 Citations
3,791 Views
9 Pages

Coupling Capillary-Driven Microfluidics with Lateral Flow Immunoassay for Signal Enhancement

  • Pooya Azizian,
  • Jasmina Casals-Terré,
  • Elena Guerrero-SanVicente,
  • Ruta Grinyte,
  • Jordi Ricart and
  • Joan M. Cabot

21 August 2023

Microfluidics has emerged as a versatile technology that is applied to enhance the performance of analytical techniques, among others. Pursuing this, we present a capillary-driven microfluidic device that improves the sensitivity of lateral flow immu...

  • Article
  • Open Access
6 Citations
2,871 Views
15 Pages

A Miniature Biomedical Sensor for Rapid Detection of Schistosoma japonicum Antibodies

  • Shengjie Hu,
  • Xuecheng Jiang,
  • Liang Yang,
  • Xue Tang,
  • Guofeng Yang,
  • Yuanyuan Hu,
  • Jie Wang and
  • Naiyan Lu

20 August 2023

Schistosomiasis, typically characterized by chronic infection in endemic regions, has the potential to affect liver tissue and pose a serious threat to human health. Detecting and screening for this disease early on is crucial for its prevention and...

  • Article
  • Open Access
7 Citations
2,250 Views
13 Pages

Magnetic Molecularly Imprinted Chitosan Combined with a Paper-Based Analytical Device for the Smartphone Discrimination of Tryptophan Enantiomers

  • Abdelhafid Karrat,
  • Juan José García-Guzmán,
  • José María Palacios-Santander,
  • Aziz Amine and
  • Laura Cubillana-Aguilera

20 August 2023

The separation of enantiomers plays a critical role in pharmaceutical development, ensuring therapeutic efficacy, safety, and patent protection. It enables the production of enantiopure drugs and enhances our understanding of the properties of chiral...

  • Article
  • Open Access
3 Citations
2,155 Views
13 Pages

Voltammetric Sensing of Nifedipine Using a Glassy Carbon Electrode Modified with Carbon Nanofibers and Gold Nanoparticles

  • Anderson M. Santos,
  • Ademar Wong,
  • Maria H. A. Feitosa,
  • Andy A. Cardenas-Riojas,
  • Sandy L. Calderon-Zavaleta,
  • Angélica M. Baena-Moncada,
  • Maria D. P. T. Sotomayor and
  • Fernando C. Moraes

19 August 2023

Nifedipine, a widely utilized medication, plays a crucial role in managing blood pressure in humans. Due to its global prevalence and extensive usage, close monitoring is necessary to address this widespread concern effectively. Therefore, the develo...

  • Article
  • Open Access
7 Citations
3,257 Views
13 Pages

18 August 2023

Herein, a simple method has been used in the fabrication of a microneedle electrode (MNE). To do this, firstly, a commercial self-dissolving microneedle patch has been used to make a hard-polydimethylsiloxane-based micro-pore mold (MPM). Then, the po...

  • Communication
  • Open Access
7 Citations
2,635 Views
9 Pages

Discrimination and Quantification of Glutathione by Cu+-Based Nanozymes

  • Meixuan Liu,
  • Chen Yan,
  • Qianyun Ye,
  • Xiaohuan Sun and
  • Jie Han

17 August 2023

Glutathione (GSH) is the most abundant low-molecular-weight biological thiol in vivo and has been linked to several diseases. The accurate quantification of GSH is therefore crucial for disease diagnosis and monitoring. In this study, we prepared sel...

  • Article
  • Open Access
5 Citations
3,780 Views
15 Pages

Development and Evaluation of a Low-Cost Triglyceride Quantification Enzymatic Biosensor Using an Arduino-Based Microfluidic System

  • Jorge E. Pliego-Sandoval,
  • Arturo Díaz-Barbosa,
  • Luis A. Reyes-Nava,
  • María Angeles Camacho-Ruiz,
  • Laura Elena Iñiguez-Muñoz and
  • Osmar Pinto-Pérez

17 August 2023

Overweight and obesity promote diabetes and heart disease onset. Triglycerides are key biomarkers for cardiovascular disease, strokes, and other health issues. Scientists have devised methods and instruments for the detection of these molecules in li...

  • Article
  • Open Access
3 Citations
2,637 Views
14 Pages

Nanosphere Lithography-Enabled Hybrid Ag-Cu Surface-Enhanced Raman Spectroscopy Substrates with Enhanced Absorption of Excitation Light

  • Zixuan Wu,
  • Jianxun Liu,
  • Zhenming Wang,
  • Lei Chen,
  • Yiwei Xu,
  • Zongjun Ma,
  • Delai Kong,
  • Dan Luo and
  • Yan Jun Liu

17 August 2023

We demonstrated a low-cost, highly sensitive hybrid Ag-Cu substrate with enhanced absorption for the excitation laser beam via the nanosphere lithography technique. The hybrid Ag-Cu surface-enhanced Raman spectroscopy (SERS) substrate consists of a C...

  • Article
  • Open Access
6 Citations
3,081 Views
16 Pages

A Critical Study on DNA Probes Attached to Microplate for CRISPR/Cas12 Trans-Cleavage Activity

  • Konstantin M. Burkin,
  • Aleksandr V. Ivanov,
  • Anatoly V. Zherdev,
  • Boris B. Dzantiev and
  • Irina V. Safenkova

17 August 2023

CRISPR/Cas12-based biosensors are emerging tools for diagnostics. However, their application of heterogeneous formats needs the efficient detection of Cas12 activity. We investigated DNA probes attached to the microplate surface and cleaved by Cas12a...

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Biosensors - ISSN 2079-6374