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Biosensors, Volume 10, Issue 12

December 2020 - 25 articles

Cover Story: Gallium-based liquid metal alloys, as metallic fluids at ambient temperature, can be readily processed into nanoparticles of a size ranging from tens to hundreds of nanometers. These nanoparticles acquire many unique but useful properties that are beneficial in biomedical applications. This review seeks to highlight exciting advances in the use of the gallium-based liquid metal nanoparticles for biomedical applications, including cancer therapy, medical imaging, and pathogen treatment. We also offer a foresight to exemplify underexplored knowledge and highlighting the research challenges faced by LMNP science and technology in expanding into applications potentially yielding clinical advances. View this paper.
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Articles (25)

  • Article
  • Open Access
6 Citations
4,670 Views
15 Pages

Rapid Multianalyte Microfluidic Homogeneous Immunoassay on Electrokinetically Driven Beads

  • Pierre-Emmanuel Thiriet,
  • Danashi Medagoda,
  • Gloria Porro and
  • Carlotta Guiducci

21 December 2020

The simplicity of homogeneous immunoassays makes them suitable for diagnostics of acute conditions. Indeed, the absence of washing steps reduces the binding reaction duration and favors a rapid and compact device, a critical asset for patients experi...

  • Article
  • Open Access
14 Citations
4,477 Views
16 Pages

21 December 2020

Protein tyrosine sulfation (PTS), a vital post-translational modification, facilitates protein–protein interactions and regulates many physiological and pathological responses. Monitoring PTS has been difficult owing to the instability of sulfa...

  • Review
  • Open Access
143 Citations
12,136 Views
22 Pages

Review of Integrated Optical Biosensors for Point-of-Care Applications

  • Yung-Tsan Chen,
  • Ya-Chu Lee,
  • Yao-Hsuan Lai,
  • Jin-Chun Lim,
  • Nien-Tsu Huang,
  • Chih-Ting Lin and
  • Jian-Jang Huang

18 December 2020

This article reviews optical biosensors and their integration with microfluidic channels. The integrated biosensors have the advantages of higher accuracy and sensitivity because they can simultaneously monitor two or more parameters. They can furthe...

  • Communication
  • Open Access
15 Citations
4,023 Views
8 Pages

Highly Sensitive Detection of CA 125 Protein with the Use of an n-Type Nanowire Biosensor

  • Kristina A. Malsagova,
  • Tatyana O. Pleshakova,
  • Rafael A. Galiullin,
  • Andrey F. Kozlov,
  • Ivan D. Shumov,
  • Vladimir P. Popov,
  • Fedor V. Tikhonenko,
  • Alexander V. Glukhov,
  • Vadim S. Ziborov and
  • Oleg F. Petrov
  • + 3 authors

18 December 2020

The detection of CA 125 protein in a solution using a silicon-on-insulator (SOI)-nanowire biosensor with n-type chip has been experimentally demonstrated. The surface of nanowires was modified by covalent immobilization of antibodies against CA 125 i...

  • Article
  • Open Access
30 Citations
4,463 Views
9 Pages

18 December 2020

In this work, a paper device consisted of a patterned paper chip, wicking pads, and a base was fabricated. On the paper chip, DNA–gold nanoparticles (DNA–AuNPs) were deposited and Hg2+ ions could be adsorbed by the DNA–AuNPs. The fo...

  • Communication
  • Open Access
12 Citations
3,957 Views
9 Pages

Development of a Graphene-Based Biosensor for Detecting Recombinant Cyanovirin-N

  • Pedro Rodrigues de Almeida,
  • André Melro Murad,
  • Luciano Paulino Silva,
  • Elibio Leopoldo Rech and
  • Elmo Salomão Alves

16 December 2020

We present a graphene-based biosensor selective to recombinant cyanovirin-N (rCV-N), an antiviral protein that has proven to be an effective microbicide to inhibit HIV replication. We modified the graphene monolayer devices with 1-pyrenebutanoic acid...

  • Article
  • Open Access
13 Citations
4,667 Views
21 Pages

Advances in the Detection of Toxic Algae Using Electrochemical Biosensors

  • Linda K. Medlin,
  • Maria Gamella,
  • Gerardo Mengs,
  • Verónica Serafín,
  • Susana Campuzano and
  • José M. Pingarrón

16 December 2020

Harmful algal blooms (HABs) are more frequent as climate changes and tropical toxic species move northward, especially along the Iberian Peninsula, a rich aquaculture area. Monitoring programs, detecting the presence of toxic algae before they bloom,...

  • Article
  • Open Access
15 Citations
4,460 Views
12 Pages

Interdigitated Sensor Optimization for Blood Sample Analysis

  • Julien Claudel,
  • Thanh-Tuan Ngo,
  • Djilali Kourtiche and
  • Mustapha Nadi

16 December 2020

Interdigitated (ITD) sensors are specially adapted for the bioimpedance analysis (BIA) of low-volume (microliter scale) biological samples. Impedance spectroscopy is a fast method involving simple and easy biological sample preparation. The geometry...

  • Review
  • Open Access
108 Citations
23,275 Views
34 Pages

15 December 2020

Recent advances in lab-on-a-chip technology establish solid foundations for wearable biosensors. These newly emerging wearable biosensors are capable of non-invasive, continuous monitoring by miniaturization of electronics and integration with microf...

  • Article
  • Open Access
11 Citations
4,148 Views
18 Pages

13 December 2020

Half of the global agricultural fresh produce is lost, mainly because of rots that are caused by various pathogenic fungi. In this study, a complementary metal-oxide-semiconductor (CMOS)-based biosensor was developed, which integrates specific DNA st...

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Biosensors - ISSN 2079-6374