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Journal of Functional Biomaterials, Volume 15, Issue 4

April 2024 - 32 articles

Cover Story: This work uses finite element analysis (FEA) to combine biomimetic Voronoi lattice structures that simulate the cancellous bone of the human jaw to advance dental implant designs. It utilizes nTOP 4.17.3 and Creo Parametric 8.0 to accurately mimic the trabecular bone's complicated porosity and biomechanical properties. The research presented improves the biomechanical performance of dental implants during dynamic mastication by varying pore diameters from 1.0 to 2.5 mm. These findings indicate the ideal pore size, which is consistent with natural bone mechanics, thereby significantly improving osseointegration and stability. Indeed, this is an important step in the development of long-lasting, patient-specific implants, thus laying the foundations for the next generation of dental treatments. View this paper
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Articles (32)

  • Article
  • Open Access
6 Citations
2,875 Views
11 Pages

Angiogenesis is vital for bone fracture healing and plays a significant role in the fate of orthopedic implants. The growth and maintenance of new blood vessels at the fracture site of patients is essential, which promotes the clinical outcome of pla...

  • Article
  • Open Access
8 Citations
2,297 Views
17 Pages

As an essential nutrient, lutein (LUT) has the ability to aid in the prevention of eye diseases, cardiovascular diseases, and cancer. However, the application of LUT is largely restricted by its poor solubility and susceptibility to oxidative degrada...

  • Article
  • Open Access
2 Citations
2,079 Views
34 Pages

Performance of Austenitic High-Nitrogen Steels under Gross Slip Fretting Corrosion in Bovine Serum

  • Alfons Fischer,
  • Philipe Telouk,
  • Christian Beckmann,
  • Saskia Heermant,
  • Adrian Wittrock,
  • Jörg Debus and
  • Markus A. Wimmer

Modular artificial hip joints are a clinical standard today. However, the release of wear products from the head–taper interface, which includes wear particles in the nm size range, as well as metal ions, have raised concerns. Depending on the...

  • Article
  • Open Access
7 Citations
3,777 Views
16 Pages

In recent years, the use of zinc (Zn) alloys as degradable metal materials has attracted considerable attention in the field of biomedical bone implant materials. This study investigates the fabrication of porous scaffolds using a Zn-1Mg-0.1Sr alloy...

  • Article
  • Open Access
2,144 Views
16 Pages

Biological and Mechanical Performance of Dual-Setting Brushite–Silica Gel Cements

  • Valentin C. Steinacker,
  • Tobias Renner,
  • Ib Holzmeister,
  • Sebastian Gubik,
  • Urs Müller-Richter,
  • Niko Breitenbücher,
  • Andreas Fuchs,
  • Anton Straub,
  • Mario Scheurer and
  • Alexander C. Kübler
  • + 1 author

Bone defects resulting from trauma, diseases, or surgical procedures pose significant challenges in the field of oral and maxillofacial surgery. The development of effective bone substitute materials that promote bone healing and regeneration is cruc...

  • Editorial
  • Open Access
1 Citations
2,456 Views
4 Pages

This Special Issue, “Functional Biomaterials and Digital Technologies in Dentistry: From Bench to Bedside”, highlights the integration of advanced materials science and digital technologies in dental and maxillofacial applications [...]

  • Article
  • Open Access
4 Citations
2,896 Views
12 Pages

In orthopaedics, erythropoietin (EPO) is applied in the preoperative management of anaemic patients, but also as a stimulating factor to assist bone regeneration due to its angiogenic and osteoinductive potential. Since orthopaedists mainly rely on t...

  • Article
  • Open Access
8 Citations
2,764 Views
13 Pages

Strontium-Doped Bioglass-Laden Gelatin Methacryloyl Hydrogels for Vital Pulp Therapy

  • Sepideh Aminmansour,
  • Ana Beatriz Gomes de Carvalho,
  • Lais Medeiros Cardoso,
  • Caroline Anselmi,
  • Maedeh Rahimnejad,
  • Renan Dal-Fabbro,
  • Erika Benavides,
  • Tiago Moreira Bastos Campos,
  • Alexandre Luiz Souto Borges and
  • Marco C. Bottino

This study aimed to develop gelatin methacryloyl (GelMA)-injectable hydrogels incorporated with 58S bioactive glass/BG-doped with strontium for vital pulp therapy applications. GelMA hydrogels containing 0% (control), 5%, 10%, and 20% BG (w/v) were p...

  • Article
  • Open Access
2 Citations
2,626 Views
12 Pages

Binary Mixtures of Meloxicam and L-Tartaric Acid for Oral Bioavailability Modulation of Pharmaceutical Dosage Forms

  • Cristina Macasoi,
  • Viorica Meltzer,
  • Ioana Stanculescu,
  • Cosmin Romanitan and
  • Elena Pincu

Binary mixtures of active pharmaceutical ingredients (API) are researched to improve the oral bioavailability of pharmaceutical dosage forms. The purpose of this study was to obtain mixtures of meloxicam and L-tartaric acid because tartaric acid impr...

  • Review
  • Open Access
15 Citations
7,319 Views
29 Pages

Zinc Oxide-Based Nanomaterials for Microbiostatic Activities: A Review

  • Alemtsehay Tesfay Reda,
  • Jae Yeon Park and
  • Yong Tae Park

The world is fighting infectious diseases. Therefore, effective antimicrobials are required to prevent the spread of microbes and protect human health. Zinc oxide (ZnO) nano-materials are known for their antimicrobial activities. Because of their dis...

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J. Funct. Biomater. - ISSN 2079-4983