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Journal of Functional Biomaterials, Volume 12, Issue 4

December 2021 - 24 articles

Cover Story: Since Biblical times, honey has been known for its cosmetic properties . In recent years, the mechanism of action of honey in the induction of wound healing has been elucidated. Moreover, honey is suitable for wound healing applications, not only for its biological properties, but also for its promising involvement in the evolution of tissue engineering nanotechnology.
The classic nanotechnology approach utilizes both dangerous and environmentally harmful compounds and conditions for synthesis. Nevertheless, now, "green chemistry" techniques allow us to obtain environmentally friendly and cost-effective nanotechnology, and honey seems to be a very promising means to realize this new “green” approach. View this paper
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Articles (24)

  • Article
  • Open Access
34 Citations
5,249 Views
12 Pages

Design of Asymmetric Nanofibers-Membranes Based on Polyvinyl Alcohol and Wool-Keratin for Wound Healing Applications

  • Diego O. Sanchez Ramirez,
  • Iriczalli Cruz-Maya,
  • Claudia Vineis,
  • Cinzia Tonetti,
  • Alessio Varesano and
  • Vincenzo Guarino

The development of asymmetric membranes—i.e., matching two fibrous layers with selected composition and morphological properties to mimic both the epidermis and dermis—currently represents one of the most promising strategies to support s...

  • Review
  • Open Access
59 Citations
7,248 Views
24 Pages

Quantum Dots: Synthesis, Antibody Conjugation, and HER2-Receptor Targeting for Breast Cancer Therapy

  • Iqra Fatima,
  • Abbas Rahdar,
  • Saman Sargazi,
  • Mahmood Barani,
  • Mohadeseh Hassanisaadi and
  • Vijay Kumar Thakur

Breast cancer is becoming one of the main lethal carcinomas in the recent era, and its occurrence rate is increasing day by day. There are different breast cancer biomarkers, and their overexpression takes place in the metastasis of cancer cells. The...

  • Feature Paper
  • Article
  • Open Access
32 Citations
3,849 Views
15 Pages

Rutin-Loaded Nanovesicles for Improved Stability and Enhanced Topical Efficacy of Natural Compound

  • Maria Chiara Cristiano,
  • Antonella Barone,
  • Antonia Mancuso,
  • Daniele Torella and
  • Donatella Paolino

Rutin is a natural compound with several pharmacological effects. Among these, antioxidant activity is one of the best known. Despite its numerous benefits, its topical application is severely limited by its physicochemical properties. For this reaso...

  • Article
  • Open Access
20 Citations
3,894 Views
19 Pages

Physical/Mechanical and Antibacterial Properties of Orthodontic Adhesives Containing Calcium Phosphate and Nisin

  • Supachai Chanachai,
  • Wirinrat Chaichana,
  • Kanlaya Insee,
  • Sutiwa Benjakul,
  • Visakha Aupaphong and
  • Piyaphong Panpisut

Enamel demineralization around orthodontic adhesive is a common esthetic concern during orthodontic treatment. The aim of this study was to prepare orthodontic adhesives containing monocalcium phosphate monohydrate (MCPM) and nisin to enable minerali...

  • Review
  • Open Access
30 Citations
4,715 Views
16 Pages

“Green” Biomaterials: The Promising Role of Honey

  • Gregorio Bonsignore,
  • Mauro Patrone,
  • Simona Martinotti and
  • Elia Ranzato

The development of nanotechnology has allowed us to better exploit the potential of many natural compounds. However, the classic nanotechnology approach often uses both dangerous and environmentally harmful chemical compounds and drastic conditions f...

  • Review
  • Open Access
63 Citations
10,636 Views
33 Pages

Polylactic Acid Piezo-Biopolymers: Chemistry, Structural Evolution, Fabrication Methods, and Tissue Engineering Applications

  • Amirhossein Farahani,
  • Abbas Zarei-Hanzaki,
  • Hamid Reza Abedi,
  • Lobat Tayebi and
  • Ebrahim Mostafavi

Polylactide acid (PLA), as an FDA-approved biomaterial, has been widely applied due to its unique merits, such as its biocompatibility, biodegradability, and piezoelectricity. Numerous utilizations, including sensors, actuators, and bio-application&m...

  • Review
  • Open Access
148 Citations
10,980 Views
31 Pages

Gold nanoparticles (AuNPs) are extremely promising objects for solving a wide range of biomedical problems. The gold nanoparticles production by biological method (“green synthesis”) is eco-friendly and allows minimization of the amount o...

  • Communication
  • Open Access
8 Citations
4,994 Views
8 Pages

The meniscus is a critical component of a healthy knee joint. It is a complex and vital fibrocartilaginous tissue that maintains appropriate biomechanics. Injuries of the meniscus, particularly in the inner region, rarely heal and usually progress in...

  • Review
  • Open Access
11 Citations
6,043 Views
24 Pages

Artificial Cell Encapsulation for Biomaterials and Tissue Bio-Nanoengineering: History, Achievements, Limitations, and Future Work for Potential Clinical Applications and Transplantation

  • Armin Mooranian,
  • Melissa Jones,
  • Corina Mihaela Ionescu,
  • Daniel Walker,
  • Susbin Raj Wagle,
  • Bozica Kovacevic,
  • Jacqueline Chester,
  • Thomas Foster,
  • Edan Johnston and
  • Jafri Kuthubutheen
  • + 3 authors

Pancreatic β-cell loss and failure with subsequent deficiency of insulin production is the hallmark of type 1 diabetes (T1D) and late-stage type 2 diabetes (T2D). Despite the availability of parental insulin, serious complications of both types...

  • Review
  • Open Access
29 Citations
7,893 Views
30 Pages

Recent Advancements in the Technologies Detecting Food Spoiling Agents

  • Reena V. Saini,
  • Prachi Vaid,
  • Neeraj K. Saini,
  • Samarjeet Singh Siwal,
  • Vijai Kumar Gupta,
  • Vijay Kumar Thakur and
  • Adesh K. Saini

To match the current life-style, there is a huge demand and market for the processed food whose manufacturing requires multiple steps. The mounting demand increases the pressure on the producers and the regulatory bodies to provide sensitive, facile,...

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J. Funct. Biomater. - ISSN 2079-4983Creative Common CC BY license