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Volume 12
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10.3390/jcm12010087
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Background:
Systematic Review

Drug-Coated Balloon versus Plain Balloon Angioplasty in the Treatment of Infrainguinal Vein Bypass Stenosis: A Systematic Review and Meta-Analysis

by
Toshihiko Isaji
*,
Yutaka Hosoi
,
Kota Kogure
,
Yohei Ichikawa
,
Keisuke Fujimaki
,
Toru Ikezoe
,
Masao Nunokawa
and
Hiroshi Kubota
Department of Cardiocascular surgery, Kyorin University, 6-20-2, Shinkawa, Mitaka 181-8611, Tokyo, Japan
*
Author to whom correspondence should be addressed.
J. Clin. Med. 2023, 12(1), 87; https://doi.org/10.3390/jcm12010087
Submission received: 17 November 2022 / Revised: 10 December 2022 / Accepted: 19 December 2022 / Published: 22 December 2022
(This article belongs to the Special Issue Clinical Frontiers in Peripheral Artery Disease)
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Abstract

The optimal endovascular therapy for vein graft stenosis (VGS) following infrainguinal arterial bypass is yet to be established. Drug-coated balloons (DCB) have rapidly improved the inferior patency outcomes of angioplasty using a conventional plain balloon (PB). This study compares the efficacy of DCBs and PBs for the treatment of infrainguinal VGS. This systematic review and meta-analysis was performed according to the PRISMA statement. Multiple electronic searches were conducted in consultation with a health science librarian in September 2022. Studies describing the comparative outcomes of angioplasty using DCBs and PBs in the treatment of infrainguinal VGS were eligible. Datasets from one randomized controlled trial and two cohort studies with a total of 179 patients were identified. The results indicated no significant difference in target lesion revascularization between DCBs and PBs (OR, 0.64; 95% CI, 0.32–1.28; p = 0.21), with no significant heterogeneity between studies. Additionally, differences in primary patency, assisted primary patency, secondary patency, and graft occlusion were not significant. Subgroup analysis showed similar effects for different DCB devices. In conclusion, DCBs showed no significant benefit in the treatment of VGS compared to PBs. Given the small population size of this meta-analysis, future trials with a larger population are desired.
Keywords: drug-coated balloon; infrainguinal artery bypass; bypass stenosis drug-coated balloon; infrainguinal artery bypass; bypass stenosis

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MDPI and ACS Style

Isaji, T.; Hosoi, Y.; Kogure, K.; Ichikawa, Y.; Fujimaki, K.; Ikezoe, T.; Nunokawa, M.; Kubota, H. Drug-Coated Balloon versus Plain Balloon Angioplasty in the Treatment of Infrainguinal Vein Bypass Stenosis: A Systematic Review and Meta-Analysis. J. Clin. Med. 2023, 12, 87. https://doi.org/10.3390/jcm12010087

AMA Style

Isaji T, Hosoi Y, Kogure K, Ichikawa Y, Fujimaki K, Ikezoe T, Nunokawa M, Kubota H. Drug-Coated Balloon versus Plain Balloon Angioplasty in the Treatment of Infrainguinal Vein Bypass Stenosis: A Systematic Review and Meta-Analysis. Journal of Clinical Medicine. 2023; 12(1):87. https://doi.org/10.3390/jcm12010087

Chicago/Turabian Style

Isaji, Toshihiko, Yutaka Hosoi, Kota Kogure, Yohei Ichikawa, Keisuke Fujimaki, Toru Ikezoe, Masao Nunokawa, and Hiroshi Kubota. 2023. "Drug-Coated Balloon versus Plain Balloon Angioplasty in the Treatment of Infrainguinal Vein Bypass Stenosis: A Systematic Review and Meta-Analysis" Journal of Clinical Medicine 12, no. 1: 87. https://doi.org/10.3390/jcm12010087

APA Style

Isaji, T., Hosoi, Y., Kogure, K., Ichikawa, Y., Fujimaki, K., Ikezoe, T., Nunokawa, M., & Kubota, H. (2023). Drug-Coated Balloon versus Plain Balloon Angioplasty in the Treatment of Infrainguinal Vein Bypass Stenosis: A Systematic Review and Meta-Analysis. Journal of Clinical Medicine, 12(1), 87. https://doi.org/10.3390/jcm12010087

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