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Volume 11
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10.3390/jcm11247409
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Review

Complex Regional Pain Syndrome after Spine Surgery: A Rare Complication in Mini-Invasive Lumbar Spine Surgery: An Updated Comprehensive Review

by
Umberto Aldo Arcidiacono
1,
Daniele Armocida
1,2,*,
Alessandro Pesce
3,
Marco Maiotti
4,
Luca Proietti
5,
Giancarlo D’Andrea
6,
Antonio Santoro
1 and
Alessandro Frati
2
1
Human Neurosciences Department, Neurosurgery Division, “Sapienza” University, 00185 Rome, Italy
2
IRCCS “Neuromed”, 86077 Pozzilli, Italy
3
Neurosurgery Unit, Santa Maria Goretti Hospital, Via Guido Reni 1, 04100 Latina, Italy
4
Villa Stuart Hospital, Orthopedic Clinic, 00135 Roma, Italy
5
Division of Spinal Surgery, IRCCS Fondazione Policlinico Universitario Agostino Gemelli, Institute of Orthopaedics, Università Cattolica del Sacro Cuore, 00168 Rome, Italy
6
“Spaziani” Hospital, 03100 Frosinone, Italy
*
Author to whom correspondence should be addressed.
J. Clin. Med. 2022, 11(24), 7409; https://doi.org/10.3390/jcm11247409
Submission received: 7 November 2022 / Revised: 2 December 2022 / Accepted: 8 December 2022 / Published: 14 December 2022
(This article belongs to the Section Orthopedics)
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Abstract

Background: Complex regional pain syndrome (CRPS) is a postoperative, misdiagnosed condition highlighted only by pain therapists after numerous failed attempts at pain control by the treating surgeon in the case of prolonged pain after surgery. It only occurs rarely after spine surgery, causing the neurosurgeon’s inappropriate decision to resort to a second surgical treatment. Methods: We performed a systematic review of the literature reporting and analyzing all recognized and reported cases of CRPS in patients undergoing spinal surgery to identify the best diagnostic and therapeutic strategies for this unusual condition. We compare our experience with the cases reported through a review of the literature. Results: We retrieve 20 articles. Most of the papers are clinical cases showing the disorder’s rarity after spine surgery. Most of the time, the syndrome followed uncomplicated lumbar spine surgery involving one segment. The most proposed therapy was chemical sympathectomy and spinal cord stimulation. Conclusion: CRPS is a rare pathology and is rarer after spine surgery. However, it is quite an invalidating disorder. Early therapy and resolution, however, require a rapid diagnosis of the syndrome. In our opinion, since CRPS occurs relatively rarely following spinal surgery, it should not have a substantial impact on the indications for and timing of these operations. Therefore, it is essential to diagnose this rare occurrence and treat it promptly and appropriately.
Keywords: spine surgery; pain; neurosurgery; complex regional pain syndrome; CRPS spine surgery; pain; neurosurgery; complex regional pain syndrome; CRPS

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MDPI and ACS Style

Arcidiacono, U.A.; Armocida, D.; Pesce, A.; Maiotti, M.; Proietti, L.; D’Andrea, G.; Santoro, A.; Frati, A. Complex Regional Pain Syndrome after Spine Surgery: A Rare Complication in Mini-Invasive Lumbar Spine Surgery: An Updated Comprehensive Review. J. Clin. Med. 2022, 11, 7409. https://doi.org/10.3390/jcm11247409

AMA Style

Arcidiacono UA, Armocida D, Pesce A, Maiotti M, Proietti L, D’Andrea G, Santoro A, Frati A. Complex Regional Pain Syndrome after Spine Surgery: A Rare Complication in Mini-Invasive Lumbar Spine Surgery: An Updated Comprehensive Review. Journal of Clinical Medicine. 2022; 11(24):7409. https://doi.org/10.3390/jcm11247409

Chicago/Turabian Style

Arcidiacono, Umberto Aldo, Daniele Armocida, Alessandro Pesce, Marco Maiotti, Luca Proietti, Giancarlo D’Andrea, Antonio Santoro, and Alessandro Frati. 2022. "Complex Regional Pain Syndrome after Spine Surgery: A Rare Complication in Mini-Invasive Lumbar Spine Surgery: An Updated Comprehensive Review" Journal of Clinical Medicine 11, no. 24: 7409. https://doi.org/10.3390/jcm11247409

APA Style

Arcidiacono, U. A., Armocida, D., Pesce, A., Maiotti, M., Proietti, L., D’Andrea, G., Santoro, A., & Frati, A. (2022). Complex Regional Pain Syndrome after Spine Surgery: A Rare Complication in Mini-Invasive Lumbar Spine Surgery: An Updated Comprehensive Review. Journal of Clinical Medicine, 11(24), 7409. https://doi.org/10.3390/jcm11247409

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