Membranes, Volume 10, Issue 8 (August 2020) – 32 articles
Cover Story (view full-size image): Macropinocytosis is a nonspecific endocytic pathway which can rapidly internalise large amounts of plasma membrane and extracellular fluid. Macropinocytosis is critical to a number of cell processes, including antigen presentation, signalling, nutrient acquisition, and nutrient sensing, and is exploited by pathogens to invade cells. Recent studies have revealed the diversity of macropinocytosis-dependent functions and pathways in a wide range of cell types. This review focuses on the current status of macropinocytosis in primary cells and compares the mechanisms of this pathway between different cell types. View this paper
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