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Antioxidants, Volume 6, Issue 2

June 2017 - 22 articles

Cover Story: The background shows a primary pneumocyte culture. In the center, there are two pictures representing a mitosis (upper left), a micronucleus (upper right), an apoptosis (lower left) and necrotic nuclei (lower right). On the right, the COMET assay is addressed showing a nucleoid with DNA fragments distributed in the tail. Furthermore, on the top of the cover, the structural formula of beta-carotin is given; on the bottom, three structures of volatile oxidative degradation products are shown. View this paper
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Articles (22)

  • Article
  • Open Access
8 Citations
7,178 Views
13 Pages

There is an ancient and prodigious history of olive trees because of their nutritional, medicinal, and traditional uses. Intensive studies have been conducted on olive leaves because they have many positive and beneficial effects for human health. In...

  • Review
  • Open Access
57 Citations
11,796 Views
22 Pages

The Importance of NADPH Oxidases and Redox Signaling in Angiogenesis

  • Rodrigo Prieto-Bermejo and
  • Angel Hernández-Hernández

Eukaryotic cells have to cope with the constant generation of reactive oxygen species (ROS). Although the excessive production of ROS might be deleterious for cell biology, there is a plethora of evidence showing that moderate levels of ROS are impor...

  • Article
  • Open Access
74 Citations
9,219 Views
14 Pages

Phenolic Compositions and Antioxidant Properties in Bark, Flower, Inner Skin, Kernel and Leaf Extracts of Castanea crenata Sieb. et Zucc

  • Phung Thi Tuyen,
  • Tran Dang Xuan,
  • Do Tan Khang,
  • Ateeque Ahmad,
  • Nguyen Van Quan,
  • Truong Thi Tu Anh,
  • La Hoang Anh and
  • Truong Ngoc Minh

In this study, different plant parts (barks, flowers, inner skins, kernels and leaves) of Castanea crenata (Japanese chestnut) were analyzed for total phenolic, flavonoid, and tannin contents. Antioxidant properties were evaluated by using 1,1-diphen...

  • Review
  • Open Access
203 Citations
17,519 Views
20 Pages

HO-1 Induction in Cancer Progression: A Matter of Cell Adaptation

  • Mariapaola Nitti,
  • Sabrina Piras,
  • Umberto M. Marinari,
  • Lorenzo Moretta,
  • Maria A. Pronzato and
  • Anna Lisa Furfaro

The upregulation of heme oxygenase-1 (HO-1) is one of the most important mechanisms of cell adaptation to stress. Indeed, the redox sensitive transcription factor Nrf2 is the pivotal regulator of HO-1 induction. Through the antioxidant, antiapoptotic...

  • Review
  • Open Access
97 Citations
16,133 Views
24 Pages

Natural phenol polymers are widely represented in nature and include a variety of classes including tannins and lignins as the most prominent. Largely consumed foods are rich sources of phenol polymers, notably black foods traditionally used in East...

  • Article
  • Open Access
9 Citations
6,156 Views
12 Pages

8th Day superoxide dismutase (SOD)-Like Supreme (SOD-Like Supreme, a free radical scavenging health product) is an antioxidant-enriched fermentation preparation with free radical scavenging properties. In the present study, the cellular/tissue protec...

  • Review
  • Open Access
113 Citations
17,179 Views
21 Pages

The importance of the tumor microenvironment for cancer progression and therapeutic resistance is an emerging focus of cancer biology. Hypoxia, or low oxygen, is a hallmark of solid tumors that promotes metastasis and represents a significant obstacl...

  • Review
  • Open Access
224 Citations
17,901 Views
19 Pages

Abnormalities of Mitochondrial Dynamics in Neurodegenerative Diseases

  • Ju Gao,
  • Luwen Wang,
  • Jingyi Liu,
  • Fei Xie,
  • Bo Su and
  • Xinglong Wang

Neurodegenerative diseases are incurable and devastating neurological disorders characterized by the progressive loss of the structure and function of neurons in the central nervous system or peripheral nervous system. Mitochondria, organelles found...

  • Review
  • Open Access
44 Citations
12,252 Views
23 Pages

Green Tea Catechins for Prostate Cancer Prevention: Present Achievements and Future Challenges

  • Valeria Naponelli,
  • Ileana Ramazzina,
  • Chiara Lenzi,
  • Saverio Bettuzzi and
  • Federica Rizzi

Green tea catechins (GTCs) are a family of chemically related compounds usually classified as antioxidant molecules. Epidemiological evidences, supported by interventional studies, highlighted a more than promising role for GTCs in human prostate can...

  • Review
  • Open Access
540 Citations
40,521 Views
9 Pages

Zinc and Oxidative Stress: Current Mechanisms

  • Dilina Do Nascimento Marreiro,
  • Kyria Jayanne Clímaco Cruz,
  • Jennifer Beatriz Silva Morais,
  • Jéssica Batista Beserra,
  • Juliana Soares Severo and
  • Ana Raquel Soares De Oliveira

Oxidative stress is a metabolic dysfunction that favors the oxidation of biomolecules, contributing to the oxidative damage of cells and tissues. This consequently contributes to the development of several chronic diseases. In particular, zinc is one...

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Antioxidants - ISSN 2076-3921