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Antioxidants, Volume 13, Issue 6

June 2024 - 132 articles

Cover Story: Nitric oxide (NO) synthesis, signaling, and scavenging is associated with relevant physiological and pathological events. In all tissues and organs, NO levels and related functions are regulated at different levels, with heme-proteins playing pivotal roles. Here, the different binding modes of NO to heme-Fe(II) are described, as well as the modulatory effects of this diatomic messenger on heme-protein functions. The ability of heme-proteins to bind NO at either the distal or proximal side of the heme and the transient interchanging of the binding site is reported. This sheds light on the regulation of O2 supply to tissues with high metabolic activity, such as the retina, where a precise regulation of blood flow is necessary to meet the demand of nutrients. View this paper
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Articles (132)

  • Review
  • Open Access
10 Citations
6,350 Views
20 Pages

The cosmetics industry plays a significant role in the global economy and consumer lifestyles. Its dynamic and adaptable characteristics make it a key player worldwide. The cosmetics industry generates enormous profits globally, injecting billions of...

  • Article
  • Open Access
13 Citations
4,730 Views
20 Pages

Black Goji Berry (Lycium ruthenicum) Juice Fermented with Lactobacillus rhamnosus GG Enhances Inhibitory Activity against Dipeptidyl Peptidase-IV and Key Steps of Lipid Digestion and Absorption

  • Kritmongkhon Kamonsuwan,
  • Vernabelle Balmori,
  • Marisa Marnpae,
  • Charoonsri Chusak,
  • Thavaree Thilavech,
  • Suvimol Charoensiddhi,
  • Scott Smid and
  • Sirichai Adisakwattana

With the global increase in hyperglycemia and hyperlipidemia, there is an urgent need to explore dietary interventions targeting the inhibition of dipeptidyl peptidase-IV (DPP-IV) and lipid digestion and absorption. This study investigated how Lactob...

  • Review
  • Open Access
6 Citations
2,221 Views
17 Pages

Induction of Nitric Oxide and Its Role in Facial Nerve Regeneration According to the Method of Facial Nerve Injury

  • Yeon Ju Oh,
  • Dong Keon Yon,
  • Yong Sung Choi,
  • Jinseok Lee,
  • Joon Hyung Yeo,
  • Sung Soo Kim,
  • Jae Min Lee and
  • Seung Geun Yeo

Nitric oxide (NO) is an important molecule in cell communication that also plays an important role in many biological processes. Given the dual role of NO in nerve degeneration and regeneration after facial nerve injury, we sought to delve deeper int...

  • Article
  • Open Access
13 Citations
3,388 Views
18 Pages

Oxidative stress (OS) and disrupted antioxidant defense mechanisms play a pivotal role in the etiology of male infertility. The alterations in reactive oxygen species (ROS) production and calcium (Ca2+) homeostasis are the main activators for the mit...

  • Article
  • Open Access
5 Citations
2,673 Views
15 Pages

Identification of Phenolic Compounds Present in Three Speedwell (Veronica L.) Species and Their Antioxidant Potential

  • Ivana Vrca,
  • Stjepan Orhanović,
  • Ivana Pezelj,
  • Karolina Sušić,
  • Valerija Dunkić,
  • Dario Kremer and
  • Marija Nazlić

Extracts from Veronica species (speedwells) are known for the various biological activities they show, such as cytotoxic, antimicrobial, anti-inflammatory, and antioxidant activities. Also, the plants from this genus are known as medicinal plants use...

  • Article
  • Open Access
4 Citations
2,460 Views
16 Pages

The Interactive Effects of the Anti-Sea Lice Pesticide Azamethiphos and Temperature on Oxidative Damage and Antioxidant Responses in the Oyster Ostrea chilensis

  • Jaime A. Montory,
  • Victor M. Cubillos,
  • Oscar R. Chaparro,
  • Paulina Gebauer,
  • Matthew R. Lee,
  • Eduardo Ramírez-Kuschel,
  • Francisco Paredes-Molina,
  • Valentina Lara-Sandoval,
  • Juan P. Cumillaf and
  • Luis P. Salas-Yanquin
  • + 1 author

Azamethiphos is used in the salmon industry to treat sea lice and is subsequently discharged into the sea, which may affect non-target species (NTS). A rise in seawater temperature could enhance the sensitivity of NTS. Thus, in the present investigat...

  • Article
  • Open Access
6 Citations
2,505 Views
15 Pages

To investigate the activities of intestinal digestive enzymes, liver antioxidant enzymes, immunological enzymes, and glucometabolic enzymes in largemouth bass (Micropterus salmoides) under the biofloc model, an experiment was conducted in 300-liter g...

  • Article
  • Open Access
4 Citations
3,235 Views
17 Pages

Active DNA Demethylase, TET1, Increases Oxidative Phosphorylation and Sensitizes Ovarian Cancer Stem Cells to Mitochondrial Complex I Inhibitor

  • Lin-Yu Chen,
  • Yao-An Shen,
  • Ling-Hui Chu,
  • Po-Hsuan Su,
  • Hui-Chen Wang,
  • Yu-Chun Weng,
  • Shiou-Fu Lin,
  • Kuo-Chang Wen,
  • Phui-Ly Liew and
  • Hung-Cheng Lai

Ten-eleven translocation 1 (TET1) is a methylcytosine dioxygenase involved in active DNA demethylation. In our previous study, we demonstrated that TET1 reprogrammed the ovarian cancer epigenome, increased stem properties, and activated various regul...

  • Article
  • Open Access
31 Citations
2,163 Views
12 Pages

From Personal Care to Coastal Concerns: Investigating Polyethylene Glycol Impact on Mussel’s Antioxidant, Physiological, and Cellular Responses

  • Cristiana Roberta Multisanti,
  • Giorgia Zicarelli,
  • Alessia Caferro,
  • Mariacristina Filice,
  • Caterina Faggio,
  • Irene Vazzana,
  • Jana Blahova,
  • Pavla Lakdawala,
  • Maria Carmela Cerra and
  • Sandra Imbrogno
  • + 1 author

Pharmaceutical and personal care products (PPCPs) containing persistent and potentially hazardous substances have garnered attention for their ubiquitous presence in natural environments. This study investigated the impact of polyethylene glycol (PEG...

  • Article
  • Open Access
2,125 Views
13 Pages

Cytotoxic Oxidative Stress Effects of Neutrophil Extracellular Traps’ Components on Cattle Spermatozoa

  • Rodrigo Rivera-Concha,
  • Marion León,
  • Aurora Prado-Sanhueza,
  • Raúl Sánchez,
  • Anja Taubert,
  • Carlos Hermosilla,
  • Pamela Uribe and
  • Fabiola Zambrano

Bovine spermatozoa are highly susceptible to oxidative stress (OS), and it is known to affect their cellular functions. The main leukocyte producers of reactive oxygen species (ROS) in mammalian semen are polymorphonuclear neutrophils (PMN). PMN acti...

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Antioxidants - ISSN 2076-3921