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Review

Bioreactors: Applications and Innovations for a Sustainable and Healthy Future—A Critical Review

by
Fernanda Palladino
1,*,†,
Paulo Ricardo Franco Marcelino
2,†,
Andersen Escobar Schlogl
1,
Álvaro Henrique Mello José
3,
Rita de Cássia Lacerda Brambilla Rodrigues
3,
Daniela Leite Fabrino
1,
Igor José Boggione Santos
1 and
Carlos Augusto Rosa
4
1
Department of Bioprocess Engineering, Federal University of São João del-Rei, Ouro Branco 36307-352, MG, Brazil
2
Center of Natural and Human Sciences, Federal University of ABC, Santo André 09280-560, SP, Brazil
3
Department of Biotechnology, Lorena Engineering School, University of São Paulo, Lorena 12602-810, SP, Brazil
4
Department of Microbiology, Institute of Biological Sciences, Federal University of Minas Gerais, Belo Horizonte 31270-901, MG, Brazil
*
Author to whom correspondence should be addressed.
†
These authors contributed equally to this work.
Appl. Sci. 2024, 14(20), 9346; https://doi.org/10.3390/app14209346
Submission received: 20 July 2024 / Revised: 7 October 2024 / Accepted: 8 October 2024 / Published: 14 October 2024
(This article belongs to the Special Issue Recent Advances in Bioreactor System: Design, Operation and Application)
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Abstract

Biotechnological processes are essential for developing economies that aim to stand out in future markets. The use of bioreactors is one of the most important unit operations of biotechnological processes, and real-time monitoring of bioreactors is essential to ensure precise bioprocess control. This review presents different types of bioreactors, sensors, and applications in other sectors. Bioreactors, controlled systems for cultivating microorganisms and cells, are essential tools in various fields, from scientific research to industrial production. The use of a variety of sensors is critical for accurate, real-time monitoring, early problem detection, reproducibility, cost reduction, and increased efficiency. These benefits are being realized in numerous applications, including biofuel production, bioremediation and leaching processes, tissue engineering, and drug manufacturing. Innovations in bioreactor technology are expanding opportunities for a more sustainable and healthier future. By developing new types of bioreactors, integrating advanced sensors, and exploring promising applications, bioreactors are playing a key role in addressing global challenges and sustainably advancing science and technology.
Keywords: bioreactors; innovations; sensors; applications bioreactors; innovations; sensors; applications

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MDPI and ACS Style

Palladino, F.; Marcelino, P.R.F.; Schlogl, A.E.; José, Á.H.M.; Rodrigues, R.d.C.L.B.; Fabrino, D.L.; Santos, I.J.B.; Rosa, C.A. Bioreactors: Applications and Innovations for a Sustainable and Healthy Future—A Critical Review. Appl. Sci. 2024, 14, 9346. https://doi.org/10.3390/app14209346

AMA Style

Palladino F, Marcelino PRF, Schlogl AE, José ÁHM, Rodrigues RdCLB, Fabrino DL, Santos IJB, Rosa CA. Bioreactors: Applications and Innovations for a Sustainable and Healthy Future—A Critical Review. Applied Sciences. 2024; 14(20):9346. https://doi.org/10.3390/app14209346

Chicago/Turabian Style

Palladino, Fernanda, Paulo Ricardo Franco Marcelino, Andersen Escobar Schlogl, Álvaro Henrique Mello José, Rita de Cássia Lacerda Brambilla Rodrigues, Daniela Leite Fabrino, Igor José Boggione Santos, and Carlos Augusto Rosa. 2024. "Bioreactors: Applications and Innovations for a Sustainable and Healthy Future—A Critical Review" Applied Sciences 14, no. 20: 9346. https://doi.org/10.3390/app14209346

APA Style

Palladino, F., Marcelino, P. R. F., Schlogl, A. E., José, Á. H. M., Rodrigues, R. d. C. L. B., Fabrino, D. L., Santos, I. J. B., & Rosa, C. A. (2024). Bioreactors: Applications and Innovations for a Sustainable and Healthy Future—A Critical Review. Applied Sciences, 14(20), 9346. https://doi.org/10.3390/app14209346

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