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Medical Sciences, Volume 6, Issue 2

June 2018 - 26 articles

Cover Story: Antimicrobial resistance is on the rise and is already a daily hindrance for intensivists combating severe infections. Without monitoring the consumption of anti-infectives and the local pathogen flora, antimicrobial therapy cannot be rationalised. Highlighting the discrepancy between the local prescription trends and the developed resistance patterns has contributed to an improved surveillance program through a multidisciplinary approach in the intensive care unit of a tertiary care hospital. View Paper here
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Articles (26)

  • Review
  • Open Access
18 Citations
6,556 Views
18 Pages

Acute exacerbations in chronic obstructive pulmonary disease (AECOPD) are associated with increased mortality, rate of hospitalization, use of healthcare resources, and have a negative impact on disease progression, quality of life and lung function...

  • Review
  • Open Access
56 Citations
7,689 Views
15 Pages

Prognosis and Follow-Up of Idiopathic Pulmonary Fibrosis

  • Estrella Fernández Fabrellas,
  • Ricardo Peris Sánchez,
  • Cristina Sabater Abad and
  • Gustavo Juan Samper

Idiopathic pulmonary fibrosis (IPF), a devastating progressive interstitial lung disease (ILD) with no known cause, is the most common and deadly of the idiopathic interstitial pneumonias. With a median survival of 3–5 years following diagnosis...

  • Article
  • Open Access
4 Citations
5,360 Views
12 Pages

Creating efficient cell lines is a priority for the biopharmaceutical industry, which produces biologicals for various uses. A recent approach to achieving this goal is the use of non-coding RNAs, microRNA (miRNA) and small interfering RNA (siRNA), t...

  • Review
  • Open Access
9 Citations
5,022 Views
11 Pages

The employment of systemic corticosteroids in the treatment of acute exacerbations of chronic obstructive pulmonary disease (COPD) has been shown to improve airway limitation, decrease treatment failure and risk of relapse, and may improve symptoms i...

  • Review
  • Open Access
19 Citations
6,714 Views
15 Pages

The Role of the Gut Microbiome in Nonalcoholic Fatty Liver Disease

  • Sanjoy Roychowdhury,
  • Praveen Conjeevaram Selvakumar and
  • Gail A.M. Cresci

Nonalcoholic fatty liver disease (NAFLD) is the leading cause of chronic liver disease, with prevalence increasing in parallel with the rising incidence in obesity. Believed to be a “multiple-hit” disease, several factors contribute to NA...

  • Review
  • Open Access
51 Citations
10,305 Views
23 Pages

Sleep Disturbances in Child and Adolescent Mental Health Disorders: A Review of the Variability of Objective Sleep Markers

  • Suman K. R. Baddam,
  • Craig A. Canapari,
  • Stefon J. R. Van Noordt and
  • Michael J. Crowley

Sleep disturbances are often observed in child and adolescent mental health disorders. Although previous research has identified consistent subjective reports of sleep disturbances, specific objective sleep markers have not yet been identified. We ev...

  • Review
  • Open Access
28 Citations
5,619 Views
13 Pages

The present review analyzes the results of recent clinical trials of β secretase inhibition in sporadic Alzheimer’s disease (SAD), considers the striking dichotomy between successes in tests of β-site Amyloid Precursor Protein-Cleavin...

  • Review
  • Open Access
11 Citations
4,921 Views
9 Pages

The immune system is an integral aspect of the human defense system and is primarily responsible for and involved in the communication between the immune cells. It also plays an important role in the protection of the organism from foreign invaders....

  • Conference Report
  • Open Access
3,034 Views
6 Pages

ENABLE 2017, the First EUROPEAN PhD and Post-Doc Symposium. Session 4: From Discovery to Cure: The Future of Therapeutics

  • Gianmarco Di Mauro,
  • Ambra Dondi,
  • Giovanni Giangreco,
  • Alexander Hogrebe,
  • Elja Louer,
  • Elisa Magistrati,
  • Meeli Mullari,
  • Gemma Turon,
  • Wouter Verdurmen and
  • Helena Xicoy Cortada
  • + 1 author

The EUROPEAN ACADEMY FOR BIOMEDICAL SCIENCE (ENABLE) is an initiative funded by the European Union Horizon 2020 program involving four renowned European Research Institutes (Institute for Research in Biomedicine—IRB Barcelona, Spain; Radboud In...

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Med. Sci. - ISSN 2076-3271