Special Issue "COPD Exacerbations"
Deadline for manuscript submissions: closed (31 March 2018)
Dr. Arturo Huerta, PhD, FCCP
Pneumology Department, Clinic Institute of Thorax, Hospital Clinic of Barcelona - Institut d'Investigacions Biomèdiques August Pi i Sunyer, University of Barcelona - Senior Specialist Emergency Medicine Department/ Medicine Section, Hospital Clinic of Barcelona, Barcelona.
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Interests: Pulmonary medicine; COPD; pneumonia
Prof. Dr. Antoni Torres
Director Pulmonary Intensive Care Unit, Respiratory Institute, Hospital Clinic of Barcelona
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Interests: respiratory medicine; epidemiology; risk factors; outcome; treatment; prevention and pathogenetic mechanisms of respiratory infections; community-acquired pneumonia; intensive care
Chronic obstructive pulmonary disease (COPD) is the most common respiratory comorbidity in the world, and has a significant impact on morbidity and mortality. Exacerbations of COPD (AECOPD)—pneumonic and non-pneumonic—are important events in the natural history of a disease, because the number of episodes of hospitalization and costs associated with COPD are associated with these clinical events. These exacerbations involve predominately neutrophilic inflammation in response to aggression by external microorganisms, pollution and sometimes of unknown cause.
In recent years, literature has focused on the different phenotypes of exacerbation (including the Asthma–COPD overlap), the impact of other causal agents of AECOPD, such as fungi, the role of eosinophils (in stable and during exacerbations) and the impact of new inhaled molecules in the prevention of these events. There is also a concern on new therapies such as macrolides to prevent exacerbations, the role of microbiome and new evidence on the use of non-invasive ventilation and emerging multidrug-resistant microorganisms as etiologic agents.
In this Special Issue of Medical Sciences we will cover the latest evidence not only on the diagnosis, but also the novelties on therapeutics from top experts in the field.
Dr. Arturo Huerta
Prof. Antoni Torres
Manuscript Submission Information
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- Chronic obstructive pulmonary disease (COPD)