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Medical Sciences, Volume 13, Issue 2

June 2025 - 48 articles

Cover Story: Prompt vascular access is crucial during cardiac arrest resuscitation. This meta-analysis of four randomized trials (9475 patients) compared intraosseous (IO) and intravenous (IV) routes in out-of-hospital cardiac arrest. While IO access was faster and more successful on the first attempt, both methods yielded similar clinical outcomes, including the return of spontaneous circulation, survival, and neurological recovery. These findings highlight IO as an efficient procedural option when IV access is not readily available. View this paper
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Articles (48)

  • Review
  • Open Access
1 Citations
2,778 Views
24 Pages

Exploring the Interplay Between Kidney Dysfunction and Cardiovascular Disease

  • Rajesh Yadav,
  • Aqsa Kaim Abubakar,
  • Richa Mishra,
  • Saurabh Gupta,
  • Neelesh Kumar Maurya,
  • Vivek Kumar Kashyap,
  • Sarvesh Rustagi,
  • Deependra Pratap Singh and
  • Sanjay Kumar

This article reveals the various types of complications that are associated with dialysis and kidney-associated disease, including left ventricular hypertrophy, heart failure, vascular heart disease, arrhythmias, diabetes mellitus, intradialytic hype...

  • Review
  • Open Access
1 Citations
2,165 Views
19 Pages

Exploring the Efficacy of Low-Temperature Plasmas on Oral Biofilms: A Scoping Review

  • Carson C. Davis,
  • Fabrízio Dias Panariello and
  • Beatriz Panariello

The rise of antibiotic resistance and the limitations of conventional therapies for managing biofilm-related oral infections highlight the urgent need for novel solutions, with low-temperature plasma (LTP) emerging as a promising alternative due to i...

  • Systematic Review
  • Open Access
2 Citations
1,954 Views
16 Pages

Intraosseous Versus Intravenous Vascular Access in Out-of-Hospital Cardiac Arrest: A Systematic Review and Meta-Analysis of Randomized Controlled Trials

  • Alhareth Alsagban,
  • Omar Saab,
  • Hasan Al-Obaidi,
  • Marwah Algodi,
  • Amy Yu,
  • Mohamed Abuelazm and
  • Chad Hochberg

Background. Establishing prompt vascular access facilitates resuscitation for out-of-hospital cardiac arrest (OHCA). While intraosseous access may decrease the time to vascular access, the impact on clinical outcomes in OHCA is unclear. Therefore, we...

  • Article
  • Open Access
1,344 Views
16 Pages

Confidential Audit of Perinatal Mortality in the Republic of Kazakhstan: A Pilot Study

  • Aizada Marat,
  • Zaituna Khamidullina,
  • Svetlana Muratbekova,
  • Kulyash Jaxalykova,
  • Bekturgan Karin,
  • Nazerke Samatova,
  • Umit Usmanova,
  • Madina Sharipova,
  • Aknur Kobetayeva and
  • Milan Terzic
  • + 2 authors

Introduction: Perinatal mortality is labeled as the loss of fetuses at or beyond 22 weeks of gestation, deaths during labor and delivery, as well as early neonatal deaths. Appropriate medical care provided in the perinatal period is an integra...

  • Communication
  • Open Access
1 Citations
2,547 Views
7 Pages

About 5–20% of patients who undergo colonoscopy, in the days and weeks following the procedure, develop various symptoms (abdominal pain, bloating, and bowel alteration) mainly related to dysbiosis induced by the propaedeutic intestinal prepara...

  • Article
  • Open Access
4 Citations
2,088 Views
10 Pages

Background: Next-generation sequencing (NGS), particularly whole-exome sequencing (WES), has become a powerful diagnostic tool for rare genetic conditions. However, its success rate varies based on the underlying genetic etiology and the population s...

  • Systematic Review
  • Open Access
3,401 Views
12 Pages

The Impact of Celiprolol in Vascular Ehlers–Danlos Syndrome: A Systematic Review of Current Evidence

  • Pandit Bagus Tri Saputra,
  • Wynne Widiarti,
  • Paulus Parholong Siahaan,
  • Rendra Mahardhika Putra,
  • Johanes Nugroho Eko Putranto,
  • Raden Mohammad Budiarto,
  • Nadya Luthfah,
  • Chaq El Chaq Zamzam Multazam,
  • Mario D’Oria and
  • Firas Farisi Alkaff

Objectives: Ehlers–Danlos syndrome (EDS) is a group of connective tissue disorders characterized by mutations affecting collagen and extracellular matrix proteins. Vascular EDS (vEDS) stands out for its severe prognosis due to the heightened ri...

  • Article
  • Open Access
1,026 Views
11 Pages

The Impact of Epithelial Inflammation in Membrane Remnants on the Outcome of Tympanoplasty

  • María Fernanda Galindo-Tapia,
  • Alejandro Esteban Deras-Quiñones,
  • Itzel Maria Montoya-Fuentes,
  • Eduardo Osiris Madrigal-Santillán,
  • Ángel Morales-González,
  • Naria A. Flores-Fuentes,
  • Liliana Anguiano-Robledo,
  • Raúl Rojas-Martínez,
  • Beatriz Montaño-Velázquez and
  • José A. Morales-González

Background: Chronic otitis media (COM) with tympanic perforation sometimes requires tympanoplasty. Many factors can interfere with surgical success; however, the histological status of the remaining epithelium of the perforation has not been studied...

  • Communication
  • Open Access
1,335 Views
12 Pages

Twice as Effective? Pressurized Intra-Thoracic Aerosol Chemotherapy: New Frontiers in Pleural Mesothelioma

  • Maria Giovanna Mastromarino,
  • Elena Guerrini,
  • Raffaele Guerrieri,
  • Gianmarco Elia,
  • Alessandra Lenzini,
  • Vittorio Aprile,
  • Greta Alì,
  • Stylianos Korasidis,
  • Marcello Carlo Ambrogi and
  • Marco Lucchi

Pressurized intra-thoracic aerosol chemotherapy (PITAC) is a novel and promising strategy for the treatment of malignant pleural effusion (MPE). PITAC enables effective pleurodesis while potentially exerting an antineoplastic effect by delivering che...

  • Article
  • Open Access
2,341 Views
14 Pages

Peripheral Prosthetic Vascular Graft Infection: A 5-Year Retrospective Study

  • Giovanni De Caridi,
  • Mafalda Massara,
  • Chiara Barilla and
  • Filippo Benedetto

Background/Objectives: Peripheral prosthetic vascular graft infection represents a very serious complication after lower limb revascularization, with amputation and mortality rates up to 70% and 30%, respectively. This study was designed to determine...

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Med. Sci. - ISSN 2076-3271