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Medical Sciences, Volume 13, Issue 1

2025 March - 32 articles

Cover Story: This study aimed to evaluate the impact of preoperative osteoporosis treatment on stress shielding and clinical outcomes in total hip arthroplasty (THA) patients. A retrospective analysis of 107 cementless THA cases revealed that patients receiving preoperative osteoporosis treatment exhibited significantly lower stress shielding grades (p = 0.001) compared to untreated patients. However, no significant differences in clinical scores were observed at one year postoperatively. These findings highlight the potential of preoperative osteoporosis treatment to reduce stress shielding, suggesting its importance in preventing long-term complications such as bone atrophy-related pain and fractures. View this paper
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Articles (32)

  • Review
  • Open Access
1 Citations
7,238 Views
13 Pages

State-of-the-Art Review on the Treatment of Axial Spondyloarthritis

  • Evripidis Kaltsonoudis,
  • Panagiota Karagianni,
  • Tereza Memi and
  • Eleftherios Pelechas

16 March 2025

The term axial spondyloarthritis (axSpA) encompasses patients with both radiographic (r-axSpA) and non-radiographic (nr-axSpA) forms of the disease. These are two entities within the same family that share many genetic and pathogenic factors, but the...

  • Article
  • Open Access
2,527 Views
12 Pages

Association Between Sociodemographic Disparities and Door to Computerized Tomography Time in Patients with Acute Ischemic Stroke Across COVID-19 Periods in the Emergency Department: A Multi-Center Cohort Study

  • Yu-Lin Hsieh,
  • Ching-Fang Tiffany Tzeng,
  • Maha Khan,
  • Andrew Shedd,
  • Thomas Damrow,
  • Dahlia Hassani,
  • Matthew Danley,
  • Jaydeep Shah,
  • Jennifer Walker and
  • Eric H. Chou

15 March 2025

Introduction: Stroke is the fifth leading cause of death and long-term disability in the United States. The current guideline for stroke management includes a 25 min timeframe from door-to-computed tomography time (DTCT). However, sociodemographic ba...

  • Article
  • Open Access
2 Citations
2,638 Views
18 Pages

Treatment of Vitamin D Deficiency in Decompensated Patients with Cirrhosis Is Associated with Improvement in Frailty

  • Raquel Díaz-Ruíz,
  • Maria Poca,
  • Eva Román,
  • Berta Cuyàs,
  • Irene Bañares,
  • Ángela Morales,
  • Elvira Hernández Martínez-Esparza,
  • Rocío Panadero,
  • Cristina Velasco and
  • Rita García-Martínez
  • + 4 authors

13 March 2025

Background/aim: Frailty is increasingly recognized as a relevant prognostic factor in patients with cirrhosis, regardless of liver failure. Vitamin D deficiency is frequent in these patients and has been related to frailty and sarcopenia, but the imp...

  • Article
  • Open Access
1 Citations
1,203 Views
9 Pages

Change in Indications and Outcomes for Stereotactic Biopsy Following Transition from Full Field Digital Mammography + Digital Breast Tomosynthesis to Full Field Synthetic Mammography + Digital Breast Tomosynthesis

  • Jose Net,
  • Antoine Hamedi-Sangsari,
  • Taylor Schwartz,
  • Mirelys Barrios,
  • Nicole Brofman,
  • Cedric Pluguez-Turull,
  • Jamie Spoont,
  • Sarah Stamler and
  • Monica Yepes

12 March 2025

Background: Synthetic 2D mammography was developed to decrease radiation exposure, but to our knowledge there have been no studies evaluating the impact of implementation of full field synthetic mammography/digital breast tomosynthesis (FFSM/DBT) on...

  • Article
  • Open Access
1,179 Views
9 Pages

Protective Effect of Daily Physical Activity Against COVID-19 in a Young Adult Population on Reunion Island

  • Camille Cazeneuve,
  • David Couret,
  • Gregorie Lebeau,
  • Wildriss Viranaicken,
  • Marie-Eve Mathieu and
  • Florian Chouchou

12 March 2025

The global fight against pandemics is a major public health issue. Epidemiological studies showed a reduced risk of the coronavirus disease 2019 (COVID-19) severity with the practice of regular physical activity (PA) in clinical populations. Here, we...

  • Systematic Review
  • Open Access
1 Citations
1,960 Views
16 Pages

FGF-23 as a Biomarker for Carotid Plaque Vulnerability: A Systematic Review

  • Joana Oliveira-Sousa,
  • Mariana Fragão-Marques,
  • Luís Duarte-Gamas,
  • Hugo Ribeiro and
  • João Rocha-Neves

10 March 2025

Background/Objectives: Carotid artery disease is a condition affecting 3% of the general population which significantly contributes to the development of cerebrovascular events. Fibroblast Growth Factor-23 (FGF-23) is a hormone that has been linked t...

  • Article
  • Open Access
1 Citations
4,771 Views
15 Pages

People who suffer from body integrity dysphoria (BID) feel a strong need to be disabled. The most common desire is for amputation or paralysis. Objectives: This study aims to gather the opinion of experts on which types of disabilities are included i...

  • Communication
  • Open Access
2 Citations
2,995 Views
10 Pages

Thermo-Ablative Fractional CO2 Lasers Combined with 1540 nm Wavelengths Is a Promising Treatment Option in Stress Urinary Incontinence

  • Maurizio Filippini,
  • Sara Elmi,
  • Jessica Sozzi,
  • Laura Pieri,
  • Irene Fusco,
  • Tiziano Zingoni and
  • Pablo González-Isaza

Background/Objectives: Stress urinary incontinence (SUI) is a common and often under-reported condition that significantly impacts quality of life. SUI is more than just a physical issue; it can also affect social interactions, mental health, and emo...

  • Article
  • Open Access
2 Citations
3,033 Views
15 Pages

Assessing Breast Cancer Awareness Among Women in Al Baha, Saudi Arabia: A Cross-Sectional Study Using the Breast Cancer Awareness Measure (BCAM)

  • Mohammad A. Albanghali,
  • Rawan K. Alnemari,
  • Rhaff B. Al Ghamdi,
  • Fatma Alzahraa M. Gomaa,
  • Taif A. Alzahrani,
  • Alya S. Al Ghamdi,
  • Batol M. Albanghali,
  • Yasser M. Kofiah,
  • Eltayeb M. Alhassan and
  • Basim A. Othman

Introduction: Breast cancer (BC) awareness and preventive practices are critical for the early detection and effective management of the disease. This study aimed to assess the level of BC awareness among women residing in Al Baha, Saudi Arabia. Meth...

  • Article
  • Open Access
2 Citations
1,189 Views
14 Pages

Impact of the SARS-CoV-2 Pandemic on the Prevalence and Incidence of Enteric Protozoa in a Spanish Tertiary-Care Hospital and a Referral Center for Tropical Diseases, 2019–2023

  • Alfredo Maldonado-Barrueco,
  • Fernando de la Calle-Prieto,
  • Marta Díaz-Menéndez,
  • Marta Arsuaga,
  • Julio García-Rodríguez and
  • Guillermo Ruiz-Carrascoso

Objetive: The aim of this study was to describe the impact of non-pharmaceutical interventions (NPIs) against SARS-CoV-2 in patients with symptoms of enteric protozoa (EP), including Blastocystis spp., Dientamoeba fragilis, Giardia lamblia, Cryptospo...

  • Article
  • Open Access
2,668 Views
9 Pages

The Examination of the Relationship Between the Number of Births with the Symptoms of Urinary Incontinence and Low Back Pain Postpartum in Greek Women

  • Eleni Katsouli,
  • Eleni-Alexandra Karathanasi,
  • Eleftheria Ntalagianni,
  • Themistoklis-Marios Terpos and
  • Anna Christakou

Background: Urinary incontinence and low back pain are often present during pregnancy and after childbirth. The aim of this study was to examine the relationship between the number of children with the occurrence of urinary incontinence and low back...

  • Article
  • Open Access
2 Citations
2,198 Views
9 Pages

Misdiagnosis of Acute Limb Ischemia from Non-Vascular Specialists Results in a Delayed Presentation and Negatively Affects Patients’ Outcomes

  • Michalis Pesmatzoglou,
  • Stella Lioudaki,
  • Nikolaos Kontopodis,
  • Ifigeneia Tzartzalou,
  • Konstantinos Litinas,
  • George Tzouliadakis and
  • Christos V. Ioannou

20 February 2025

Background/Objectives: Acute Limb Ischemia (ALI) is a vascular emergency which is accompanied by a significant risk of limb loss or even death. Rapid restoration of arterial perfusion using surgical and/or endovascular techniques is crucial for limb...

  • Article
  • Open Access
3 Citations
2,035 Views
10 Pages

16 February 2025

Whole blood viscosity is a test for blood stasis and is an ideal evidence-based pathology parameter that is largely undervalued and retrogressing in clinical utilization. Coagulation profiles as indices of haemostasis are available but limited to cen...

  • Article
  • Open Access
1 Citations
1,912 Views
10 Pages

Outcomes in Acute Decompensated Congestive Heart Failure Admissions with Chronic Liver Disease: A Nationwide Analysis Using the National Inpatient Sample

  • Vivek Joseph Varughese,
  • Vignesh Krishnan Nagesh,
  • Pratiksha Moliya,
  • Nelson Gonzalez,
  • Emelyn Martinez,
  • Hata Mujadzic,
  • Maggie James,
  • Abraham Lo and
  • Simcha Weissman

13 February 2025

AIM: The aim of our study was primarily to analyze hospital outcomes for acute decompensated heart failure (ADHF) admissions with a comorbid diagnosis of chronic liver disease (CLD). METHODS: The NIS was used to select ADHF admissions. The population...

  • Article
  • Open Access
4 Citations
2,336 Views
12 Pages

The Success and Safety of Endoscopic Retrograde Cholangiopancreatography in Surgically Altered Gastrointestinal Anatomy

  • Samuel Han,
  • Jennifer M. Kolb,
  • Steven A. Edmundowicz,
  • Augustin R. Attwell,
  • Hazem T. Hammad,
  • Sachin Wani and
  • Raj J. Shah

11 February 2025

Background/Objectives: Performing endoscopic retrograde cholangiopancreatography (ERCP) in surgically altered gastrointestinal anatomy remains challenging, frequently necessitating the use of forward-viewing endoscopes. Given the challenge in endosco...

  • Article
  • Open Access
1 Citations
2,927 Views
11 Pages

9 February 2025

Rheumatoid arthritis (RA) is a chronic autoimmune disorder that affects the joints, causing swelling, pain, stiffness, and functional decline. This study aims to clarify the prevalence and risk factors of RA based on sex and age among Korean adults,...

  • Review
  • Open Access
2 Citations
2,916 Views
11 Pages

Radiological and Clinical Outcome Differences Between Standard and Short Stem in Reverse Total Shoulder Arthroplasty: A Systematic Review

  • Mauro Ciuffreda,
  • Antongiulio Lentini,
  • Giuseppe Francesco Papalia,
  • Domenico Grasso,
  • Pierangelo Za,
  • Rocco Papalia and
  • Giacomo Rizzello

9 February 2025

Background: In recent years, the use of short cementless humeral components in reverse total shoulder arthroplasty (RTSA) has increased. This systematic review aimed to compare the radiological and clinical outcomes of uncemented RTSA using short ver...

  • Review
  • Open Access
2,881 Views
17 Pages

A Scoping Review on Cognition in Myelodysplastic Syndromes: Advances and Challenges

  • Anna Tsiakiri,
  • Konstantinos Frigkas,
  • Pinelopi Vlotinou,
  • Menelaos Papoutselis,
  • Foteini Christidi,
  • Efstratios Karavasilis,
  • Ioannis Kotsianidis,
  • Nikolaos Kourkoutsakis,
  • Konstantinos Vadikolias and
  • Konstantinos Liapis

7 February 2025

Background/Objectives: Myelodysplastic syndromes (MDS) are clonal hematopoietic disorders characterized by ineffective hematopoiesis and a risk of progression to acute myeloid leukemia (AML). Cognitive impairments, including deficits in memory, atten...

  • Opinion
  • Open Access
2,144 Views
10 Pages

Acute Hepatic Porphyria Should Be Included in the Diagnostic Work-Up of Patients with Resistant Hypertension or Suspected Secondary Hypertension

  • Paulo de Lima Serrano,
  • Bruno de Mattos Lombardi Badia,
  • João Paulo Barile,
  • Patrícia Marques Mendes,
  • Renan Brandão Rambaldi Cavalheiro,
  • Kaliny Oliveira Peixoto,
  • Igor Braga Farias,
  • Roberta Ismael Lacerda Machado,
  • Daniel Delgado Seneor and
  • Paulo Sgobbi
  • + 2 authors

6 February 2025

Secondary hypertension and resistant hypertension may result from potentially treatable acquired or hereditary diseases. Inherited Metabolic Disorders are not routinely included in the differential diagnosis of these contexts associated with hyperten...

  • Review
  • Open Access
14 Citations
19,698 Views
29 Pages

Update on the Complications and Management of Liver Cirrhosis

  • Hiba Fadlallah,
  • Diala El Masri,
  • Hisham F. Bahmad,
  • Wassim Abou-Kheir and
  • Jad El Masri

5 February 2025

Liver cirrhosis represents the advanced pathological stage of chronic liver disease, characterized by the progressive destruction and regeneration of the hepatic parenchyma over years, culminating in fibrosis and disruption of the vascular architectu...

  • Case Report
  • Open Access
2 Citations
2,244 Views
10 Pages

An Unusual Case of Uremic Tumoral Calcinosis with Atypical Manifestation in a Patient on Peritoneal Dialysis: Case Report and Review of the Literature

  • Esperanza Moral Berrio,
  • Roger A. Cox Conforme,
  • Raúl Elías,
  • José C. De La Flor,
  • Celia Rodríguez Tudero,
  • María Dolores Sánchez de la Nieta-García,
  • Rocío Zamora González-Mariño and
  • Carmen Vozmediano Poyatos

29 January 2025

Background: Uremic tumoral calcinosis (UTC) is a rare yet severe complication of chronic kidney disease (CKD), predominantly occurring in patients undergoing renal replacement therapy (RRT). It is characterized by extensive soft tissue calcifications...

  • Systematic Review
  • Open Access
2,918 Views
18 Pages

Placebo-Controlled Trials in the Management of Crohn’s Disease: An Umbrella Review of Meta-Analyses

  • Richard Silva,
  • José Nunes de Azevedo,
  • Jorge Pereira Machado and
  • Jorge Magalhães Rodrigues

29 January 2025

Introduction: Crohn’s disease is a chronic inflammatory bowel disease characterized by abdominal pain, diarrhea, and other symptoms. It can lead to significant complications and impact patients’ quality of life. Therefore, effective manag...

  • Article
  • Open Access
3 Citations
2,289 Views
9 Pages

Preoperative Osteoporosis Treatment Reduces Stress Shielding in Total Hip Arthroplasty

  • Ryuichi Kanabuchi,
  • Yu Mori,
  • Kazuyoshi Baba,
  • Hidetatsu Tanaka,
  • Yasuaki Kuriyama,
  • Hideki Fukuchi,
  • Hiroki Kawamata and
  • Toshimi Aizawa

28 January 2025

Background: Total hip arthroplasty (THA) is a widely used surgical intervention for hip osteoarthritis (HOA), with a rising demand driven by an aging population. Osteoporosis is associated with increased risks of bone loss and implant loosening after...

  • Article
  • Open Access
1,069 Views
24 Pages

Evaluating the Stress State and the Load-Bearing Fraction as Predicted by an In Vivo Parameter Identification Method for the Abdominal Aorta

  • Jerker Karlsson,
  • Jan-Lucas Gade,
  • Carl-Johan Thore,
  • Carl-Johan Carlhäll,
  • Jan Engvall and
  • Jonas Stålhand

27 January 2025

Background: Arterial mechanics are crucial to cardiovascular functionality. The pressure–strain elastic modulus often delineates mechanical properties. Emerging methods use non-linear continuum mechanics and non-convex minimization to identify...

  • Review
  • Open Access
8 Citations
6,317 Views
11 Pages

11 January 2025

Depression poses significant challenges to global healthcare systems and impacts the quality of life of individuals and their family members. Recent advancements in artificial intelligence (AI) have had a transformative impact on the diagnosis and tr...

  • Article
  • Open Access
2 Citations
2,442 Views
22 Pages

Circulating microRNAs as Biomarkers of Various Forms of Epilepsy

  • Elena E. Timechko,
  • Kristina D. Lysova,
  • Alexey M. Yakimov,
  • Anastasia I. Paramonova,
  • Anastasia A. Vasilieva,
  • Elena A. Kantimirova,
  • Anna A. Usoltseva,
  • Albina V. Yakunina,
  • Irirna G. Areshkina and
  • Diana V. Dmitrenko

8 January 2025

Background: Epilepsy is a group of disorders characterized by a cluster of clinical and EEG signs leading to the formation of abnormal synchronous excitation of neurons in the brain. It is one of the most common neurological disorders worldwide; and...

  • Article
  • Open Access
1 Citations
3,043 Views
14 Pages

Whole-Genome Sequencing of Resistance, Virulence and Regulation Genes in Extremely Resistant Strains of Pseudomonas aeruginosa

  • Nerlis Pajaro-Castro,
  • Erick Diaz-Morales,
  • Kenia Hoyos and
  • Cristhian Ibañez-Bersinger

3 January 2025

Background/Objectives: Pseudomonas aeruginosa is a clinically significant opportunistic pathogen, renowned for its ability to acquire and develop diverse mechanisms of antibiotic resistance. This study examines the resistance, virulence, and regulato...

  • Article
  • Open Access
1 Citations
3,563 Views
10 Pages

Impact of Continuous Positive Airway Pressure on Patient Outcomes in Acute Cardiogenic Pulmonary Edema Within Physician-Led Prehospital Care

  • Tatjana Jevtić Drkić,
  • Armin Šljivo,
  • Kenan Ljuhar,
  • Amela Ahmić Tuco,
  • Lamija Hukić Fetahović,
  • Emina Karamehić,
  • Amna Palikuća Ljuhar,
  • Jasna Husejinbegović Musić,
  • Šejla Brković Jusufbegović and
  • Amina Valjevac
  • + 4 authors

1 January 2025

Background: CPAP has been shown to be particularly beneficial in the management of acute cardiogenic pulmonary edema by reducing both preload and afterload, thus decreasing the work of breathing and improving oxygenation. Methods: This study was a pr...

  • Review
  • Open Access
4 Citations
4,786 Views
16 Pages

Long-Term Management of Sleep Apnea-Hypopnea Syndrome: Efficacy and Challenges of Continuous Positive Airway Pressure Therapy—A Narrative Review

  • Zishan Rahman,
  • Ahsan Nazim,
  • Palvi Mroke,
  • Khansa Ali,
  • MD Parbej Allam,
  • Aakash Mahato,
  • Mahveer Maheshwari,
  • Camila Sanchez Cruz,
  • Imran Baig and
  • Ernesto Calderon Martinez

30 December 2024

Sleep apnea-hypopnea syndrome (SAHS) is a respiratory disorder characterized by cessation of breathing during sleep, resulting in daytime somnolence and various comorbidities. SAHS encompasses obstructive sleep apnea (OSA), caused by upper airway obs...

  • Article
  • Open Access
1 Citations
2,518 Views
12 Pages

29 December 2024

Background: NIPT is a widely implemented method for prenatal screening of chromosomal disorders. Its introduction initiated the practice of counseling women pre- and post-analytically. Since the test’s usage is established in different conditio...

  • Review
  • Open Access
1 Citations
2,767 Views
20 Pages

Pathophysiological Features of Remodeling in Vascular Diseases: Impact of Inhibitor of DNA-Binding/Differentiation-3 and Estrogenic Endocrine Disruptors

  • Vincent Avecilla,
  • Mayur Doke,
  • Sandeep Appunni,
  • Muni Rubens,
  • Venkataraghavan Ramamoorthy and
  • Jayanta Kumar Das

26 December 2024

Vascular diseases, such as hypertension, atherosclerosis, cerebrovascular, and peripheral arterial diseases, present major clinical and public health challenges, largely due to their common underlying process: vascular remodeling. This process involv...

  • Review
  • Open Access
2 Citations
4,307 Views
12 Pages

Benefits of Cilostazol’s Effect on Vascular and Neuropathic Complications Caused by Diabetes

  • Diego Castro Musial,
  • Maria Eduarda Ajita and
  • Guilherme Henrique Souza Bomfim

24 December 2024

Diabetes mellitus (DM) is a global health concern with a rising incidence, particularly in aging populations and those with a genetic predisposition. Over time, DM contributes to various complications, including nephropathy, retinopathy, peripheral a...

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Med. Sci. - ISSN 2076-3271