Infectious Bovine Respiratory Diseases in Adult Cattle: An Extensive Necropsic and Etiological Study
by
,
Laëtitia Dorso
1,2,*
,
Maud Rouault
1,3,
Claire Barbotin
1,
Christophe Chartier
1,3 and
Sébastien Assié
1,3 1
INRAE, Oniris, BIOEPAR, 44300 Nantes, France
2
Pathology Unit for Large Animals, Oniris, La Chantrerie, 44307 Nantes, France
3
Clinic for Ruminants, Oniris, La Chantrerie, 44307 Nantes, France
*
Author to whom correspondence should be addressed.
Animals 2021, 11(8), 2280; https://doi.org/10.3390/ani11082280
Submission received: 12 July 2021
/
Revised: 26 July 2021
/
Accepted: 29 July 2021
/
Published: 2 August 2021
(This article belongs to the Collection Cattle Diseases)
Simple Summary
Animal necropsy can accurately determine the cause of its death. However, studies based on large-scale necropsies of cattle are rare because they require special skills and equipment. This study places particular emphasis on fatal respiratory diseases in adult cattle. The objectives of this study were to assess the importance of respiratory diseases as a cause of death in adult cattle and to determine associated lesions as well as associated pathogens of infectious causes of respiratory diseases in adult cattle. This study showed that respiratory diseases are the second leading cause of death in adult cattle after digestive diseases. Among respiratory diseases, we noticed a strong predominance of infectious pulmonary lesions, mainly characterized by fibrinous, hemorrhagic and/or necrotic bronchopneumonia. These bronchopneumonia are mainly associated with the detection of a bacteria, Mannheimia haemolytica. This study suggests that Mannheimia haemolytica should be included in the differential diagnosis of BRD in adult cattle.
Abstract
In young cattle, bovine respiratory disease (BRD) is a major cause of death and Mannheimia haemolytica is a frequent pathogen. Knowledge of fatal BRD in adult cattle is more limited. We assessed the importance of infectious BRD as a cause of death in adult cattle and determined the associated pathogens. We analyzed data from 737 adult cattle necropsies at the Pathology Unit for Large Animals at Oniris, Nantes, France over a 6 year period (2013–2019). Each carcass was subjected to a complete necropsy. Lungs showing macroscopic lesions were classified into three categories: infectious primary pulmonary (IPP) lesions, thromboembolic pneumonia (TEP) and others (aspiration pneumonia, verminous pneumonia, and local extension of an extra-pulmonary inflammatory process). Half of the lungs with IPP macroscopic lesions were sampled for histology and submitted for polymerase chain reaction. BRD was the second leading cause of death (15.7%) after digestive diseases (32.2%). A strong predominance of IPP lesions (42.3%) and TEP lesions (39.6%) was also demonstrated. In IPP macroscopic lesions, fibrinous, hemorrhagic and/or hecrotic (FHN) bronchopneumonia accounted for 77.6% of macroscopic lesions. Mannheimia haemolytica was significantly associated with FHN bronchopneumonia macroscopic lesions. This study suggests that Mannheimia haemolytica should be included in the differential diagnosis of BRD in adult cattle.
